A renowned researcher and Professor of Medical Oncology at the UCL Cancer Institute, Dr Ledermann has dedicated more than 30 years to advancing the treatment and understanding of gynaecologic cancers. His clinical and academic work has driven significant improvements in care - particularly the use of PARP inhibitors for women with homologous recombination deficient ovarian cancers - through practice-changing clinical trials and a relentless commitment to evidence-based innovation.
As a founding member of ENGOT, former Director of the Cancer Research UK & UCL Cancer Trials Centre, and a Senior Investigator for the National Institute of Health Research (NIHR), Dr Ledermann has built a legacy of leadership in cancer research, driving progress in the treatment of ovarian and cervical cancers. Under his guidance, the Cancer Trials Centre became one of the leading national and international hubs for gynaecologic cancer clinical trials, shaping treatment guidelines and improving outcomes for women around the world.
Dr Ledermann’s influence extends far beyond the lab and clinic. He has served in numerous leadership roles in the global gynaecologic cancer community, including as:
Council Member of the International Gynaecologic Cancer Society
Vice President of the European Society of Gynaecological Oncology (ESGO)
Chair of the NCRI UK Gynaecological Cancer Trials Group
Chair of the Rare Tumour Working Group within the Gynaecologic Cancer InterGroup (GCIG)
Chair or Group leader of Consensus Conferences and Guidelines Committees on behalf of ESMO and ESGO
Subject Editor for ESMO Gynaecological Cancer Practice Guidelines
In addition to his many honours and affiliations, he is a Fellow of the UK Academy of Medical Sciences, a widely respected editor and author with more than 320 published papers. His clear, compassionate voice has been heard at countless scientific meetings worldwide, where he continues to inspire the next generation of clinicians and researchers.
Dr Ledermann gained his degree in medicine at UCL and trained in internal medicine and oncology in London and then in Toronto, receiving his Doctorate in Medicine in 1990 and becoming a Fellow of the Royal College of Physicians in 1993. His impact as a mentor, educator and leader has touched institutions and individuals across the globe, making him a true champion of progress in gynaecologic oncology.
The IGCS Lifetime Achievement Award is presented to individuals who have made significant and lasting contributions to the field over the course of their careers. Dr Ledermann exemplifies this legacy through a career marked by visionary leadership, unwavering dedication, and a profound commitment to improving the lives of women affected by gynaecologic cancers.
Dr Ledermann said: “I’m deeply honoured to receive this award from the International Gynaecologic Cancer Society. It has been a privilege to work alongside so many dedicated colleagues, both in the UK and internationally, whose collaboration and friendship have been central to our work to advance care for women with gynaecologic cancers. This recognition reflects a collective effort from the research teams and clinical trial units to the patients who have participated in our studies. I remain committed to supporting the next generation of researchers and clinicians as we continue to drive progress in this field.”
Department of Oncology
We research vital strands in Oncology, including brain cancer biology, cancer metastasis, glioblastoma and treatment resistance.
CRUK City of London Centre
The Cancer Research UK City of London (CoL) Centre is a world class hub for cancer biotherapeutics, bringing together researchers from four of the central London Cancer Research UK Centres.
Cancer Research UK Drug-DNA Interactions
The Cancer Research UK Drug-DNA Interactions Research Group was established in 1995 with the aim of contributing to the development of new and improved cancer therapies based on DNA as a target.