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Hidden side effects: antibiotics affect gut for a year

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  • Hidden side effects: antibiotics affect gut for a year

Eastman Researchers Professor Mike Wilson and Dr David Spratt have co-authored a new paper which reveals long-term consequences of a single course of antibiotics.

The study found that the drugs disrupt the normal makeup of microorganisms in the gut for as long as a year – and potentially lead to antibiotic resistance.

By contrast, microorganisms in the saliva showed signs of renewal in just a few weeks.

David said: “The research has revealed that a course of antibiotics not only disturbs the normal make-up of our stomachs but also enriches genes associated with antibiotic resistance.

“This long-term interference adds even more weight to the call to withhold antibiotics except when absolutely necessary.”

The researchers also found that British participants began the study with more antibiotic resistance than their Swedish counterparts.

Read the full paper in the Journal of the American Society for Microbiology and press release.

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Drug to treat aggressive leukaemia approved for use in adults
Fluorescence microscopy image of immune cells, showing blue-stained nuclei surrounded by green cell membranes with red marker signals indicating specific proteins or activity within the cells.

Research

Drug to treat aggressive leukaemia approved for use in adults

Adult patients with aggressive leukaemia will soon be able to receive a breakthrough immunotherapy, developed by UCL researchers, on the NHS after approval by NICE.

Millions could benefit from faster prostate cancer scan
healthy prostate scan

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Millions could benefit from faster prostate cancer scan

Results of the PRIME trial involving UCL Medical Sciences researchers have found that a quicker, cheaper MRI scan was just as accurate at diagnosing prostate cancer as the current 30-40 minute scan.

10 September 2025

UCL Cancer Institute awarded Athena SWAN Gold
Athena Swan Gold Award

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UCL Cancer Institute awarded Athena SWAN Gold

The UCL Cancer Institute has been awarded Athena SWAN Gold in recognition of its sustained commitment to advancing gender equality in higher education and research.

20 May 2025

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