Key contacts
We are based at the UCL Royal Free Hospital Campus, Hampstead.
Our work
Our research focuses on inflammation conditions, including amyloidosis, rheumatology and metabolism and inflammation are burgeoning areas in medical science. We collaborate across disciplines to improve our understanding of inflammatory mechanisms, driving towards breakthroughs to improve diagnostics and therapeutic strategies for patients grappling with these challenging conditions.
For amyloidosis, investigations aim to understand the abnormal accumulation of misfolded proteins leading to organ damage. We explore the novel diagnostic tools, therapeutic interventions, and molecular pathways involved in amyloid formation. We work towards targeted treatments that address the root causes of this disorder, enhancing patient outcomes.
In rheumatology, the emphasis is on unravelling the complexities of autoimmune and inflammatory diseases affecting the musculoskeletal system and connective tissues, and the organ-based complications characterised by vasculopathy, excessive remodelling and fibrosis. Advances in genomics, immunology, and precision medicine contribute to personalized therapies for conditions like Raynaud's and scleroderma.
The Metabolism and Inflammation groups research investigates diagnostics and therapeutics for non-communicable diseases. Studies using epidemiology and omics (genomics and metabolomics) approaches are aimed to improve the health of low/middle-income communities by investigating the medical burden of non-communicable diseases (NCDs) and consequence of inflammation and metabolic dysfunction.
Amyloidosis
The Centre for Amyloidosis includes the NHS National Amyloidosis Centre and the Wolfson Drug Discovery Unit.
Rheumatology (Royal Free)
We investigate connective tissue diseases, disorders characterised by inflammation, tissue damage and remodeling or excessive repair.
Metabolism and Inflammation
The Centre of Metabolism and Inflammation explores diagnostics and therapeutics for non-communicable diseases with an omics approach.
Teaching
Colleagues from this department contribute to our undergraduate BSc and specialist MSc programmes.
Applied Medical Sciences BSc
Bridge the gap between science and medicine. Find out how top scientific research leads to improvements in clinical practice and patient outcomes.
Human Tissue Repair MSc/MRes
Build your specialist skills in human tissue repair after injury on our globally recognised MSc.
Respiratory Clinical Science MSc
This MSc focuses on studying the scientific and clinical basis of respiratory diseases.
Our centres
We are formed of the following three centres.
Centre for Amyloidosis
This centre comprises the NHS National Amyloidosis Centre, funded by the Department of Health to provide diagnostic and management advisory services for the national caseload of patients with amyloidosis and hereditary periodic fever syndromes, and the Wolfson Drug Discovery Unit.
Professor of Medicine (Inflammation)
Head: Centre of Metabolism and Inflammation
Centre for Rheumatology, Royal Free Campus
Connective tissue diseases are a spectrum of disorders characterised by inflammation, tissue damage and remodelling or excessive repair often leading to destruction and degeneration of the target organ and replacement with scar or fibrotic tissue.
Centre of Metabolism and Inflammation
The Centre of Metabolism and Inflammation aims to investigate diagnostics and therapeutics for Non-Communicable Diseases
Professor Mohammed Al Maadheed
Head: Centre of Metabolism and Inflammation
Head: Centre of Metabolism and Inflammation
