Dissecting the molecular details of how these processes work will provide greater insight into HIV-1 pathogenesis and inform future antiviral strategies. We are also working on SARS-CoV-2 virus-host interactions with emphasis on innate immunity.
Our current research focus
- Dissecting virus-host interactions that support successful HIV replication in T cells and understanding what makes a T cell permissive for HIV-1.
- Determining how HIV-1 reprograms T cells during infection and the implications for viral persistence and reservoir formation.
- Determining how SARS-CoV-2 VOCs have evolved to better suppress and evade human innate immune sensing and antiviral restriction factors.
- Evaluating antiviral therapeutics and inhibitors.
We have also teamed up with the Towers' lab to study SARS-CoV-2 and its interaction with host cells.
Explore the Jolly Lab
People and Research
Learn more about our members and the research we conduct at the Jolly Lab.
Collaborators
The scientists and experts who work collaboratively with the Jolly Lab.
Public Engagement
We strongly believe that communicating our work to the general public and being actively involved in public engagement are important aspects of being a scientist.
Work with Us
If you are eligible for fellowship schemes and/or interested in joining our lab as a PhD student or postdoctoral position, we would love to hear from you.
Contact Us
The Clare Jolly Lab is based at the Cruciform Building on UCL's Bloomsbury Campus.
The Jolly Lab is funded by the Wellcome Trust.
