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Gynae-Oncology Trials

A list of our early phase gynae-oncology trials which are open to recruitment at University College London Hospitals.

Additional early phase clinical trials recruiting Gynae-Oncology cohorts may be found in the Advanced Solid Tumour Trials Portfolio page.

CRAIN A phase 1b TiTE-CRM dose escalation clinical trial of tolinapant in combination with standard radical chemoradiotherapy in cervical cancer
IRAS Number:	1004372
Principal Investigator:	Dr Asma Sarwar
Drug Class/Treatment:	Tolinapant (ASTX660) - non-peptidomimetic antagonist of the cellular and X-linked inhibitors of apoptosis proteins (cIAP1/2 and XIAP). Combination with standard radical chemoradiotherapy
Patient Population:	Cervical Cancer
Trial Hosted By - NIHR UCLH Clinical Research Facility (CRF)

MOV18-02 (EPS101-10-02) EPS101-10-02: A Phase 1b Open-Label Trial of MOv18 IgE in Patients with Advanced Ovarian Cancer
IRAS Number:	1009485
Principal Investigator:	Dr Rowan Miller
Drug Class/Treatment:	Mov18 IgE (IgE Antibody)
Patient Population:	Advanced Ovarian Cancer Advanced epithelial ovarian, fallopian tube cancer, or primary peritoneal cancer with histologically- high-grade serous or endometrioid features or a predominantly serous/ endometrioid component.
Trial Hosted By - NIHR UCLH Clinical Research Facility (CRF)

Principal Investigator(s)

Dr. Rowan Miller

Dr Rowan Miller

Consultant Medical Oncologist

Dr Michael Flynn

Consultant Medical Oncologist

Highlights in Medical Sciences

Millions could benefit from faster prostate cancer scan

Research

Millions could benefit from faster prostate cancer scan

Results of the PRIME trial involving UCL Medical Sciences researchers have found that a quicker, cheaper MRI scan was just as accurate at diagnosing prostate cancer as the current 30-40 minute scan.

UCL Cancer Institute awarded Athena SWAN Gold

Award

UCL Cancer Institute awarded Athena SWAN Gold

The UCL Cancer Institute has been awarded Athena SWAN Gold in recognition of its sustained commitment to advancing gender equality in higher education and research.

New Dean of Medical Sciences appointed

Announcement

New Dean of Medical Sciences appointed

Internationally recognised clinician scientist, Professor Emma Morris, will take up the role of Dean of UCL's Faculty of Medical Sciences in August 2025.