Dr Anna Barnes is principal clinical scientist for the Siemens PETMRI scanner located at the UCH Macmillan Cancer Centre and part of the Institute of Nuclear Medicine. Projects include applications in oncology, neurology and cardiology. She also holds an honorary senior lecturer position funded by HEE/NIHR fellowship and is currently a primary PhD supervisor for the CDT in Medical Imaging programme. She is HPC registered as a Chartered Scientist having completed her medical physics training through the Institute of Physics and Engineering in Medicine in 1997.
Anna has experience in both emission tomography and magnetic resonance imaging technology and image processing. Her research has concentrated on finding robust imaging biomarkers for understanding mechanisms of disease or differential diagnosis. The use of imaging biomarkers relies on their robustness across subjects and scanners. Imaging biomarkers based on fractal analysis or graph theory metrics of resting state fMRI can be used to study the effect of pathologies, such as Schizophrenia, on brain function. In addition, other imaging biomarkers such as grey matter density or volume can be used to look at the influence of genes on brain function and structure that are linked to risk for schizophrenia in non-symptomatic relatives and controls. Anne is currently applying these methods to simultaneous PET and MR imaging in Neurology as well as exploring the use of normal databases to inform differential diagnosis of dementia and seizure focus in epilepsy in conjunction with projects lead by Prof Jon Schott, and Prof Matthias Koepp, Inst of Neurology. She has recently been awarded a NIHR fellowship to look at standardisation and harmonisation of whole body diffusion weighted imaging in oncology in partnership with Dr David Atkinson and Dr Shonit Punwani, Centre for Medical Imaging at UCL and in collaboration with Dave Collins and Prof Martin Leach at the Institute for Cancer Research, UK. She is also involved in supporting projects lead by Prof Brian Hutton and Dr Kris Thielemans as part of an EPSRC grant focussed on complementary methods in PET and MRI.
For more information on CMI PI's full list of current and completed reserach grants, please follow links below: