UCL Centre for Medical Image Computing


Erwin Alles & Mark Pinnock - CMIC/WEISS Joint Seminar Series

29 March 2023, 1:00 pm–2:00 pm


Erwin Alle & Mark Pinnock - CMIC/WEISS Joint Seminar Series

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UCL Centre for Medical Image Computing and Wellcome/EPSRC Centre for Interventional and Surgical Sciences


Charles Bell House G03 & Zoom
43 - 45 Foley Street
United Kingdom

Speakers: Dr Erwin Alles & Mark Pinnock  - UCL WEISS 

Title:  Real-time, interventional and multimodal optical ultrasound imaging &  Joint training of contrast enhancement and super-resolution networks

Abstract: (Real-time, interventional and multimodal optical ultrasound imaging)

Different medical imaging modalities offer different trade-offs. For example, ultrasound imaging offers real-time, depth-resolved imaging and excellent soft-tissue contrast, but limited tissue or molecular specificity. X-ray imaging offers large-area imaging at high resolution, but subjects patients to a radiation dose. MRI imaging offers excellent tissue specificity, but yields limited spatial and temporal resolution and is incompatible with metal instruments. Ideally, multiple imaging modalities are hence simultaneously applied to obtain the most accurate information possible. However, such multimodal imaging is not trivial. For instance, ultrasound imaging is conventionally performed using electronic transducers, which are costly to miniaturise, can be susceptible to electromagnetic (EM) interference, and can cause significant artefacts in X-ray or MRI images.    
Recently, an all-optical alternative to electronic technology was developed at UCL, where ultrasound waves are both generated and detected using light. Using off-shelf fibre-optic technology, optical ultrasound (OpUS) imaging probes are readily miniaturised to facilitate interventional applications, and in addition immune to EM interference and thus inherently compatible with MRI or CT imaging. During this seminar, I will present the work done to date by the MISI group on multimodal optical ultrasound imaging, and demonstrate its potential for real-time and multimodal interventional applications.

1st Bio:  Dr Erwin Alles received his BSc, MSc and PhD degrees from Delft University of Technology, The Netherlands, where he received a broad training in sound, ranging from room acoustics to oil and gas exploration and medical imaging. He was a Visiting Scholar at Michigan State University and a post-doctoral researcher at the Institute of Cancer Research before he joined UCL in 2014. Since 2020 he is a lecturer in the department of Medical Physics and Biomedical Engineering at UCL, and a member of the Wellcome/EPSRC centre for Interventional and Surgical Sciences (WEISS). He leads the Multimodal Interventional Sensing and Imaging group (MISI), which develops novel devices and technologies that enable imaging and sensing in a range of interventional procedures. His current research interests include optical ultrasound imaging, ultrasound image reconstruction, and multimodal and interventional applications of ultrasound.

Abstract: (Joint training of contrast enhancement and super-resolution networks)
Jointly training CNNs for super-resolution and contrast enhancement tasks in interventional CT through use of a shared vector quantization layer.

2nd Bio: Mark Pinnock is a final year PhD student with the CANDI group, working on deep learning in interventional CT.