MBPhD Programme





Current Position:

Qualified 2002

PhD title:

An investigation of the Role of Sex Chromosone Synopsis in Meiotic Sex Chromsome Inactivation and Fertility

Principal Supervisor:

Paul Burgoyne

Funding Source:

National Institute for Medical Research

PubMed-accessible Publications:

Turner,J.M. , Mahadevaiah,S.K., Benavente,R., Offenberg,H.H., Heyting,C., & Burgoyne,P.S. (2000) Analysis of male meiotic "sex body" proteins during XY female meiosis provides new insights into their functions. Chromosoma., 109, 426-432.

Turner,J.M ., Burgoyne,P.S., & Singh,P.B. (2001) M31 and macroH2A1.2 colocalise at the pseudoautosomal region during mouse meiosis. J.Cell Sci., 114, 3367-3375.

Mahadevaiah,S.K., Turner,J.M., Baudat,F., Rogakou,E.P., de Boer,P., Blanco-Rodriguez,J., Jasin,M., Keeney,S., Bonner,W.M., & Burgoyne,P.S. (2001) Recombinational DNA double-strand breaks in mice precede synapsis. Nat.Genet., 27, 271-276.

Burgoyne,P.S., Ojarikre,O.A., & Turner,J.M. (2002) Evidence that postnatal growth retardation in XO mice is due to haploinsufficiency for a non-PAR X gene. Cytogenet.Genome Res., 99, 252-256.

Turner,J.M. , Mahadevaiah,S.K., Elliott,D.J., Garchon,H.J., Pehrson,J.R., Jaenisch,R., & Burgoyne,P.S. (2002) Meiotic sex chromosome inactivation in male mice with targeted disruptions of Xist. J.Cell Sci., 115, 4097-4105.

Saunders,P.T., Turner,J.M., Ruggiu,M., Taggart,M., Burgoyne,P.S., Elliott,D., & Cooke,H.J. (2003) Absence of mDazl produces a final block on germ cell development at meiosis. Reproduction., 126, 589-597.

Szot,M., Grigoriev,V., Mahadevaiah,S.K., Ojarikre,O.A., Toure,A., von Glasenapp,E., Rattigan,A., Turner,J.M., Elliott,D.J., & Burgoyne,P.S. (2003) Does Rbmy have a role in sperm development in mice? Cytogenet.Genome Res., 103, 330-336.

Hoyer-Fender,S., Czirr,E., Radde,R., Turner,J.M., Mahadevaiah,S.K., Pehrson,J.R., & Burgoyne,P.S. (2004) Localisation of histone macroH2A1.2 to the XY-body is not a response to the presence of asynapsed chromosome axes. J.Cell Sci., 117, 189-198.

Turner,J.M. (2005) Sex chromosomes make their mark. Chromosoma., 114, 300-306.

Turner,J.M. , Mahadevaiah,S.K., Fernandez-Capetillo,O., Nussenzweig,A., Xu,X., Deng,C.X., & Burgoyne,P.S. (2005) Silencing of unsynapsed meiotic chromosomes in the mouse. Nat.Genet., 37, 41-47.

Turner,J.M. (2006) X-inactivation: close encounters of the X kind. Curr.Biol., 16, R259-R261.

Turner,J.M., Mahadevaiah,S.K., Ellis,P.J., Mitchell,M.J., & Burgoyne,P.S. (2006) Pachytene asynapsis drives meiotic sex chromosome inactivation and leads to substantial postmeiotic repression in spermatids. Dev.Cell., 10, 521-529.

Burgoyne,P.S., Mahadevaiah,S.K., & Turner,J.M. (2007) The management of DNA double-strand breaks in mitotic G2, and in mammalian meiosis viewed from a mitotic G2 perspective. Bioessays., 29, 974-986.

Reynard,L.N., Turner,J.M., Cocquet,J., Mahadevaiah,S.K., Toure,A., Hoog,C., & Burgoyne,P.S. (2007) Expression analysis of the mouse multi-copy X-linked gene Xlr-related, meiosis-regulated (Xmr), reveals that Xmr encodes a spermatid-expressed cytoplasmic protein, SLX/XMR. Biol.Reprod., 77, 329-335.

Takada,Y., Isono,K., Shinga,J., Turner,J.M., Kitamura,H., Ohara,O., Watanabe,G., Singh,P.B., Kamijo,T., Jenuwein,T., Burgoyne,P.S., & Koseki,H. (2007) Mammalian Polycomb Scmh1 mediates exclusion of Polycomb complexes from the XY body in the pachytene spermatocytes. Development., 134, 579-590.

Turner,J.M. (2007) Meiosis 2007--where have we got to and where are we going? Chromosome.Res., 15, 517-521.

Turner,J.M . (2007) Meiotic sex chromosome inactivation. Development., 134, 1823-1831.