MBPhD Programme


RYTEN (nee Bar-Isaac), Mina 



Current Position:

Qualified 2004

PhD title:

Principal Supervisor:

Prof Geoff Burnstock

Funding Source:

Departmental Research Studentship (UCLMS)

Description of Project:

Puinergic Signalling in Developing and Regenerating Skeletal Muscle

PubMed-accessible Publications:

Ryten,M. , Hoebertz,A., & Burnstock,G. (2001) Sequential expression of three receptor subtypes for extracellular ATP in developing rat skeletal muscle. Dev.Dyn., 221, 331-341.

Ryten,M. , Dunn,P.M., Neary,J.T., & Burnstock,G. (2002) ATP regulates the differentiation of mammalian skeletal muscle by activation of a P2X5 receptor on satellite cells. J.Cell Biol., 158, 345-355.

Cheung,K.K., Ryten,M., & Burnstock,G. (2003) Abundant and dynamic expression of G protein-coupled P2Y receptors in mammalian development. Dev.Dyn., 228, 254-266.

Ryten,M. , Yang,S.Y., Dunn,P.M., Goldspink,G., & Burnstock,G. (2004) Purinoceptor expression in regenerating skeletal muscle in the mdx mouse model of muscular dystrophy and in satellite cell cultures. FASEB J., 18, 1404-1406.

White,N., Ryten,M., Clayton,E., Butler,P., & Burnstock,G. (2005) P2Y purinergic receptors regulate the growth of human melanomas. Cancer Lett., 224, 81-91.

Ryten,M ., Koshi,R., Knight,G.E., Turmaine,M., Dunn,P., Cockayne,D.A., Ford,A.P., & Burnstock,G. (2007) Abnormalities in neuromuscular junction structure and skeletal muscle function in mice lacking the P2X2 nucleotide receptor. Neuroscience., 148, 700-711.

Shabbir,M., Ryten,M., Thompson,C., Mikhailidis,D., & Burnstock,G. (2007) Characterization of calcium-independent purinergic receptor-mediated apoptosis in hormone-refractory prostate cancer. BJU.Int., .

Shabbir,M., Ryten,M., Thompson,C., Mikhailidis,D., & Burnstock,G. (2008) Purinergic receptor-mediated effects of ATP in high-grade bladder cancer. BJU.Int., 101, 106-112.