MBPhD Programme


POWELL, Benjamin Edward


July 2010

Current Position: 

Post PhD: MBBS Year 6 - Preparation for Practice

PhD title: 

Roles of 5-hydroxymethylcytosine in pluripotency, nuclear reprogramming and tumourigenesis

Principal Supervisor: 

Professor Stefan Beck - Cancer Institute

Funding Source: 

Whitehead Institute, MIT

Description of Project:



Dawlaty MM, Breiling A, Le T, Raddatz G, Barrasa MI, Cheng AW, Gao Q, Powell BE, Li Z, Xu M, Faull KF, Lyko F, Jaenisch R. Combined deficiency of Tet1 and
Tet2 causes epigenetic abnormalities but is compatible with postnatal development. Dev Cell. 2013 Feb 11;24(3):310-23. doi: 10.1016/j.devcel.2012.12.015. Epub 2013 Jan 24.

Dawlaty MM, Ganz K, Powell BE, Hu YC, Markoulaki S, Cheng AW, Gao Q, Kim J, Choi SW, Page DC, Jaenisch R. Tet1 is dispensable for maintaining pluripotency
and its loss is compatible with embryonic and postnatal developme