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Seminar: How cells exploit their shape during collective cell decisions and migration

06 December 2022, 11:00 am–12:00 pm

Seminar series

I will show some of our recent integrated predictive simulation and in vivo work focussed on understanding how cells coordinate during angiogenesis and neural crest collective migration

This event is free.

Event Information

Open to

All

Availability

Yes

Cost

Free

Organiser

Philip Pearce

Location

Lankester Lecture Theatre
University College London, Malet Pl
London
WC1E 6BT

UCL-Crick Mathematical Biology Meeting:

Speaker: Katie Bentley (Francis Crick Institute)

Cells change shape, often to take on quite dramatically different forms while they move and interact. I will show some of our recent integrated predictive simulation and in vivo work focussed on understanding how cells coordinate during angiogenesis and neural crest collective migration, which predicts that the cells ability to adaptively change shape, which in turns feedback to alter their interactions, signalling and/or notch decisions lie at the heart of robust and timely collective migration and decision-making.

Contact the organisers:

For more information or to sign up please contact: 


Relevant papers:

1.    Zakirov et al Active perception during angiogenesis: filopodia speed up Notch selection of tip cells in silico and in vivo. Royal society PTB 2021 : 

2.    Alhashem et al  Notch controls the cell cycle to define leader versus follower identities during collective cell migration e Life 2022

3.   (perspectives piece on our embodied agent based modelling approach) Bentley et al. Do Endothelial cells dream of eclectic shape? Dev Cell 2014: