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Rob Tetley's picture

MRC Skills Development Fellow, Mao Lab

r.tetley@ucl.ac.uk

Europe PMC | PubMed | ORCID

Research Synopsis

An inevitable consequence of interacting with the outside world is that our bodies will experience some form of injury. Therefore, the tissues that line the inside and outside of our bodies (epithelia) must have mechanisms through which they can repair themselves. While we understand the biochemical signals required for tissue repair well, we know much less about how the mechanical properties of epithelial tissues and their surrounding environment influence the repair process. I use the Drosophila wing disc to investigate the role of tissue mechanics in epithelial wound healing. Using a combination of live imaging, quantitative image analysis, mechanical perturbation and computational modelling, I have begun to demonstrate how tissue mechanics can be exploited to accelerate wound healing.
 

Biography

2014 | PhD Developmental Biology, University of Cambridge
2010 | MPhil Developmental Biology, University of Cambridge
2009 | MSc Developmental Cell Biology, University of Sussex
2007 | BSc (Hons) Zoology, University of Nottingham
 

Awards

2016 | MRC Skills Development Fellowship
2009 | Wellcome Trust PhD Studentship
 

Funders

Medical Research Council

Research Themes

Cytoskeleton and cell cortex, Polariy and cell shape, Tissue mechanics, Tissue repair

Technology

Light microscopy