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LMCB - MRC Laboratory for Molecular Cell Biology

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Gautam Dey's picture

Postdoctoral Research Associate, Baum Lab

g.dey@ucl.ac.uk

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Evolutionary cell biology of the cell cycle

Research Synopsis

I am interested in the mechanisms that drive the remodelling of the nucleus through the cell cycle, and their origins in the cell cycle machinery of the archaeal ancestors of eukaryotes. I study nuclear remodelling using the model fission yeast Schizosaccharomyces pombe. In parallel, I have helped to develop a live-imaging platform for a thermophilic archaeal model species, Sulfolobus, that has a eukaryote-like phasic cell cycle - little is known about the cell biology of extant archaeal lineages.

I received my PhD from Stanford University’s Department of Chemical and Systems Biology in 2015, where I worked with Tobias Meyer on the evolution of human gene regulatory modules. Before moving to California, I worked with Satyajit Mayor and Mukund Thattai at the National Centre for Biological Sciences, Bangalore, India, on genome-scale screens for endocytosis in Drosophila.

Biography

2015-present | Postdoctoral Research Associate, LMCB
2017-2018 | Marie Sklodowksa-Curie Individual Fellow
2015 | PhD, Chemical and Systems Biology, Stanford University
2009 | MSc. (By Research), Cell Biology, National Centre for Biological Sciences, Bangalore, India
2006 | BSc. (Honours), Biochemistry, University of Delhi, Delhi, India
 

Awards

2017 | Marie Sklodowska-Curie Individual Fellowship
2009 | Stanford Graduate Fellowship in Science and Engineering
 

Funders

Current | Wellcome Trust
Previous | BBSRC, European Commission, Marie Sklodowska-Curie Individual Fellowship
 

Research Themes

Cytoskeleton, Polarity and cell shape, Nucleus, Nuclear remodeling, Cell division
 

Technology

Light microscopy, Electron microscopy, Super-resolution microscopy, Bioinformatics