LMCB - MRC Laboratory for Molecular Cell Biology


Publication in Developmental Cell for Baum Lab

Myosin II Controls Junction Fluctuations to Guide Epithelial Tissue Ordering
Curran et al, Developmental Cell, DOI 10.1016/j.devcel.2017.09.018

Highlights from the article:
    •    Fluctuations in junction length cause neighbor exchange events without morphogenesis
    •    The variance in junction tension determines how actomyosin influences T1 rates
    •    Globally increasing junctional actomyosin levels inhibits neighbor exchange
    •    A developmental increase in isotropic junction tension refines cellular packing
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