LMCB - MRC Laboratory for Molecular Cell Biology


New publication in Developmental Cell for Baum lab

Normal cells in the human body only divide when they need to, but cancer cells keep continuously growing and dividing, even in a tumour packed full of other cells. The Baum lab has found that activating a cancer-causing gene in normal cells changes the way that they divide, making them stiffer and more able to push against their surroundings. These cells were able to create space and divide successfully underneath a stiff gel, while normal cells were not. This helps to explain why cancer cells are so efficient at dividing in crowded and stiff tumours. Read the article in Developmental Cell.