Researchers

Working alongside the Trustees, Professor Humphrey Hodgson and Professor Clare Selden supervise the day-to-day research produced by a team of researchers, who are comprised of a mixture of PhD Students, Research Assistants and other Academics.

Click the profile tab of each team member to find out more.

IMPORTANT NOTICE:The Charity, 'The Liver Group'(1024533) has now been closed in order to reopen as a Charitable Incorporated Organisation (CIO) called 'The Liver Group Charity'(1166985). This is the only material change and is a result of compliance with Charity Commission guidance.

Researchers

Eloy

Research Associate

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Sweta

Researcher

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Tom

Researcher

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Trustees and Patron

David Holbrook

Chairman and Trustee

Sweta Chandel

Researcher

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Eloy Erro

Where did you study?

I studied in Spain where I did Bachelors’ and Masters degrees in Agricultural Engineering. I gained a lot of laboratory experience including mammalian cell culture, bacteria culturing and carrying out PCR, whilst doing these experiments and moved to a laboratory in the Netherlands (Erasmus Fellowship) where I carried out my thesis. I was offered an internship at The Centre for Ecology and Hydrology (Oxford) where I learnt about genetic modification. After completing this I decided to move to London and my previous laboratory experience and knowledge allowed me to get a job at the Liver Group.

Roles and responsibilities within the Liver Group:

I mainly work with James in the running of the BAL; this includes monolayer cell culture, encapsulating the cells in alginate and biomass 3D growth in a Single Use Bioreactor (SUB) to obtain the bioartificial liver. We collaborate with a company in Germany who have helped us to develop the cell encapsulation machine they produced to be specifically relevant for encapsulating mammalian cells in GMP-acceptable conditions. My engineering experience helped me to discuss adjustments to the design. Together we are constantly trying to develop and improve the system and so we have been involved in improving the drainage system and testing the flows.

How long have you worked here?

I started here in October 2007 and I’m the second longest working team member currently working for the Liver Group.

Favourite part of the job?

It is a very satisfying feeling after a complete successful Bioartficial Liver has been produced and tested. It is also very satisfying to see the progress of the project when the results are getting better after some small modifications of the research.

Does your role overlap with others/who do you work with?

As mentioned before I mainly work with James on the project. Nonetheless, Sunil and Sherri are also doing vital work by helping us with the cell preparation, encapsulation set up and media preparation used for the Bioartificial liver and we occasionally have some help from other PhD students within the group.

Do you have any “out-of-work” interests?

I like sports such as cycling and playing squash. In my free time I also like designing and building small structures made of wood and metal. I am also into playing music, mainly guitar and I enjoy cinema and photography.

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Sweta Chandel

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Where did you study?

I studied biomedical science as my undergrad at St Georges University in London and then went on to do a MSc in Molecular Medicine and Cancer Research at Brunel.

Roles and responsibilities within the Liver Group:

Working on the BAL project.

How long have you worked here?

I started working here in April 2019

Does your role overlap with others/who do you work with?

I work mainly with Eloy and Tom

Do you have any out-of-work interests?

Rock climbing, baking, travelling, and lifting weights - trying to be like Arnold Schwarzenegger in the gym!

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Tom

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David Holbrook

Where did you study/what is your academic background?

I qualified in medicine from St. Thomas’s Hospital Medical School (now part of King’s) in 1983. I also have a degree in English from Oxford and an MBA from Harvard Business School.

What do you do when you aren't busy with the Liver Group?

I am currently working at Cambridge University as part of a team within the University creating and investing in academic spin out companies.

How did you come to be a part of the Liver Group

I have been involved as a Trustee since 2016.

What do you enjoy about working with the Liver Group?

Working with exceptional clinicians and researchers in the field of liver medicine.

What do you do outside of work

I enjoy a wide range of scientific, cultural and artistic interests

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Professor Clare Selden

Professor Selden is an experienced researcher in the field of hepatology and one of the lead researchers on the Bio-Artificial Liver project. After completing her PhD at the University of London she held a number of research posts; principally with the Gastroenterology Unit of the Royal Postgraduate Medical School, but also with the Experimental Medicine Unit at the Wellcome Medical Research Institute in New Zealand. Currently she holds the post of Reader in the Department of Medicine within the Royal Free Campus of the University College Medical School.

She states that she 'chose a career in medical research after graduating because I wanted to work on an application that might eventually reach the clinic. That was many moons ago. I think we may now be close to that possibility. The Liver Group Charity was started to help us raise enough money to carry out the research for developing a liver machine to treat patients with liver disease as much as kidney dialysis does for patients with kidney disease today. With the generosity of our donors we have come a long way since its inception in 1993, and I am very grateful to the kindness of our donors, and also to the several members of our scientific team who have contributed to the work we have done over the years and my current colleagues'.

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Prof. Sir Roger Penrose

Patron

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Sue Eggleton

Trustee

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Professor Sir Roger Penrose

Sir Roger Penrose is an English mathematical physicist, philosopher and Emeritus Rouse Ball Professor of Mathematics at the Mathematical Institute of the University of Oxford, as well as Emeritus Fellow of Wadham College. Roger Penrose was born in 1931 in Colchester, Essex. Though he was originally more attracted to medicine than mathematics, he became internationally renowned for his scientific work in mathematical physics, in particular his contributions to general relativity and cosmology.

He was elected a Fellow of the Royal Society of London in 1972 and a Foreign Associate of the United States National Academy of Sciences in 1998. He has received a number of prizes and awards, including the 1988 Wolf Prize for physics which he shared with Stephen Hawking for their contribution to our understanding of the universe.

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Elizaveta Zotova

An accountant by background, Sue has over 20 years of Board level experience as Director of Finance and Deputy CEO in NHS Hospitals and as Director of Resources in smaller start up organisations. In addition Sue is a Non-Executive Director and Chair of the Audit committee of one of the largest housing associations in the South of England.

She has been involved in the Liver Group for 3 years and believes that she has 'been lucky enough to join at a time to see the many years of dedicated research beginning to deliver the vision of a bio artificial liver. The benefits this could bring to patients with acute liver disease is immense and I am privileged to be part of the team'.



Where did you study/ what is your academic background?

I have a degree in Economics from Brunel and I became an accountant under the body CIPFA (the Chartered Institute of Public Finance and Accountancy).

What do you do when you aren’t busy with the Liver Group?

I previously worked as a Finance Director and Deputy Chief Executive of a large acute hospital. I then got involved in start up organisations and the NHS Trust development authority which aimed to turn around financially failing hospitals. I have also just finished a term of 9 years as the non executive director of a housing association.

How did you come to be a part of the Liver Group?

I met Humphrey Hodgson at the Hammermith Hospital and through him and my boss at the time I became a trustee of the charity.

What do you enjoy about working with the Liver Group?

I love the vision it has of what we hope to achieve, I enjoy working with something that aims to make health care better for people as this is the background I come from.

What do you do outside of work?

I like to keep fit particularly by playing golf and I also like going to concerts and the theatre.

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Elizaveta

Researcher

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Barry Fuller

Researcher

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Kay Glendinning MBE

Trustee

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Sarah Bates

Trustee

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Elizaveta Zotova

Where did you study?

I did my Bachelors degree in Biomedical Sciences at Kings College London and my Masters in Advanced Biomedical Imaging at University College London. During my year at UCL developed essential skills for performing basic methodological aspects of health care research and understanding and reviewing published research. The course centered around the current preclinical imaging methods and their application in different organs and how these methods are validated and implemented in the preclinical environment. For my dissertation, entitled "Exploring the viability of the BAL biomass when exposed to liver failure plasma" I worked in a research laboratory. During this time, I gained valuable laboratory skills, particularly working with primary cell cultures, preparation of culture media and biomass testing and cell visualization under light and fluorescence microscope. In addition, I assisted the team with multiple tasks like alginate preparation and small scale cell encapsulation.

Roles and responsibilities within the Liver Group:

Conducting laboratory tests and experiments. Gathering and recording research and data. Prepare specimens for analysis and observation. Analyzing specimens using light and digital fluorescence microscopy. Operating computer and laboratory equipment. Perform calculations and advanced analysis on lab observations. Present findings to peers at conferences or in published articles. Follow strict safety rules and procedures to eliminate contamination of specimens.

I started working here in May 2015

How long have you worked here?

I started here in March 2020.

Favourite part of the job?

Being part of this great team!

Do you have any "out-of-work" interests?

Tennis, dancing, traveling and my cat.

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Barry Fuller

Barry is professor in Surgical Science in the department of surgical biotechnology at UCL.

Research Summary

Research into low temperature preservation of cells, tissues and organs for clinical applications; effects of ischaemia / reperfusion injury in surgery; organ-specific metabolic effects of chemotherapy, surgery and transplantation; liver and pancreas studies; translational research on hypothermic liver perfusion for transplantation; stem cells and tissue engineering in hepatic support and vascular biology.

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Mary Collier

Mary has practised as a commercial lawyer for 15 years focused primarily on entertainment and intellectual property contract work. In recent years she has expanded her work to the charity sector and represents a number of small charities. She is excited to be the newest recruit to the board of The Liver Group, where she hopes her experience will prove useful to the team in bringing its truly revolutionary technology to market.

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Sarah Bates

Trustee

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Sarah Bates

Sarah Bates is a Chairman or director of a number of listed companies, a pension fund Trustee and member of pension fund and charitable investment committees. Sarah has a B.A. (Hons) from Cambridge University and an MBA from the London Business School. She was Chief Investment Officer and Chief Executive of a UK institutional asset management business. She states that she 'is involved in the Liver Group because of the extraordinary commitment of the team, the excitement of the scientific work they do and the massive impact it could make on patients with acute liver disease'.

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Martin Giles

Martin Giles retired in 2019 from a career of almost 30 years with BP p.l.c., where his last responsibilities in his last position, as Vice President, Corporate Finance, covered the funding of the activities of the BP group as well as its pension obligations. He joined BP in 1989 as a research chemist, following post-doctoral research at Nagoya University under Professor Noyori Ryoji (winner of the 2001 Nobel Prize for Chemistry). He has held a variety of commercial roles in China, the US, Hong Kong and the UK, serving on a number of company boards in a wide range of countries. Martin holds a degree and DPhil in organometallic chemistry from the University of Oxford, and also studied corporate finance at the London Business School. He became a trustee of The Liver Group Charity in 2018, excited by the chance to help the team to realise - through practical application of leading science - a truly life-saving option for patients at great risk.

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Elise

Charity Assistant Administrator

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Take a look at our Trustees:

Trustees