Module Database

Information for module PHAR2002

This module is available for 2017/18

If you're a member of UCL you can add this module to your personalised course list

This information is for guidance only. If you are an UCL undergraduate interested in studying one of these courses, you must seek permission from both the providing department and your 'home' department. Appearance in this database is not a guarantee that a course is running in any particular academic year.

Module code:PHAR2002 (Add to my personalised list)
Title:General and Systematic Pharmacology
Credit value:1
Division:Division of Biosciences
Module organiser (provisional):Professor Talvinder Sihra
Organiser's location:Dept. Neuroscience, Physiology & Pharmacology
Available for students in Year(s):2
Module prerequisites:PHOL1001/2 or similar. 
Module outline:A comprehensive lecture course designed for students of Pharmacology and Biomedical Sciences (Drug Mechanisms stream only). The course covers the mechanisms of action and uses of the major groups of drugs and important aspects of pharmacokinetics and drug toxicity. Students must have a sound knowledge of physiology and biochemistry. 
Module aims:1.To provide a sound knowledge of the actions of many of the important groups of drugs used in medicine. 2.In particular, to emphasise, insofar as is known, the detailed mechanism of action of drugs at the molecular, cellular or tissue level, citing wherever possible experimental evidence. 3.To show how drugs (and toxins) may be of use in elucidating physiological processes. 4.To provide an understanding of how the time-course of drug action may depend on the processes of drug absorption, distribution, metabolism and excretion, and how changes in the concentrations of drugs in the body can be described quantitatively (pharmacokinetics). 5.To show how the activity of a drug is related to its chemical structure and how structural changes can modify therapeutic efficacy or toxicity. 6.To consider the problems of designing, developing and conducting clinical trials of new drugs.  
Module objectives:On completion of the course, students will be able to give thorough written and brief verbal accounts of the following topics. 1.Receptor / transduction mechanisms. 2.Drug action in the peripheral nervous system (pns) and on tissues innervated by the pns. 3.Drug action in the cardiovascular, renal & respiratory systems. 4.Chemotherapy: drugs used in cancer & in viral, bacterial or fungal infection. 5.Drug action in inflammation; diabetes; the control of fertility. 6.Drug action on neurotransmission in the central nervous system (cns). 7.Drugs in schizophrenia, Parkinson�s disease, epilepsy, anxiety, depression, general anaesthesia and analgesia. Drug dependence 8.Design, & development of new drugs; relation of drug structure to pharmacological activity. Drug toxicity; clinical trials of new drugs. 9.The time course of drug action and the factors determining the plasma concentration-time relationships of clinically important drugs. 10.The solution of elementary problems in pharmacokinetics given the appropriate physico-chemical, distribution and clearance data of example drugs.  
Key skills provided by module: 
Module timetable: 
Module assessment:Pharmacokinetics test (60 minutes) 10.00%
Unseen three-hour written examination 75.00%
Essay (1,500 words) 5.00%
In-course assessment (60 minutes) 10.00% 
Notes:This module runs over Terms 1 AND 2. >>>>>>>>> Assessment details: (1) PHARMACOKINETICS PROBLEM SOLVING PAPER (10%, 50min); (2) IN-COURSE ASSESSMENT-1 (10%, 1hr, 10 MCQs + 3 SAQs); (3) ESSAY ASSIGNMENT - 5% - (1,500 words); (4) IN COURSE ASSESSMENT-2 (formative but compulsory, 1hr, 20 MCQs); (5) Written Examination (75%, 3hr, 20 MCQs + 4 SAQs + 2 essays). >>>>>>>>> Recommended textbooks: Pharmacology - Rang, Dale, Ritter & Moore (recent edition). Basic and Clinical Pharmacology - Katzung (recent edition). Pharmacology condensed - Dale & Haylett (Revision aid).  
Taking this module as an option?:No 
Link to virtual learning environment (registered students only)
Last updated:2017-08-17 12:46:46 by uckltss