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Information for module CLNE0009

This module is available for 2019/20

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Module code:CLNE0009 (Add to my personalised list)
Title:Basic Neuroscience and Investigation of Nervous System
Credit value:30
Division:Institute of Neurology
Module organiser (provisional):Prof Adrian Isaacs, Dr Jennifer Pocock and Dr Rohan De Silva
Organiser's location:Queen Square
Available for students in Year(s):
Module prerequisites:First or upper second class (2:1) Honours degree in neuroscience or related biological science (e.g. physiology, psychology, pharmacology, biochemistry); or a medical degree from a UK University, or an overseas qualification of an equivalent standard. 
Module outline:The module gives an introduction to basic cellular neuroscience and some of the applications used for research in neuroscience. Building on basic principles it will also give a comprehensive overview of genetics, cellular biology, principles of neurotransmission and the functions of cells of the nervous system. 
Module aims:The aim of the module is to provide students with an understanding of the cellular and molecular mechanisms of disease and some of the investigatory tools used such as EEG, TMS, MRI, fMRI, along with learning basic brain anatomy. This material provides the theoretical basis for topics explored in other modules on the programme. 
Module objectives:At the end of the module the students will have an understanding of (i) the genetics of disorders of the central nervous system, (ii) brain metabolism, neurotransmitters and neurodegeneration & iii) list the function of different cells in the nervous system. This understanding will be supported by workshops on laboratory techniques, brain anatomy, basic cell science & neuropathology, EEG, MRI, fMRI and TMS. 
Key skills provided by module: 
Module timetable: 
Module assessment:

PG FHEQ Level 7

  • Standard assessment pattern:
    • Unseen short answer exam (3 hours) 100.00%

UG FHEQ Level 7

  • Standard assessment pattern:
    • Unseen short answer exam (3 hours) 100.00%
Notes:Indicative titles of lectures - please note these may change from year to year. The cell biology of the neuron; Cells of the nervous system I and II; Introduction to medical genetics; Principles of neurogenetics; GWAS; The importance of genetics and molecular biology in neurodegenerative diseases; Genetics of neurological disease; Brain anatomy; Ionotropic receptors; Voltage gated channels; Biophysics of the action potential; General principles of neurotransmission and neuropharmacology; Synaptic plasticity; Non-ionotropic receptors; Cellular mechanisms of neuroprotection; Calcium: function and dysfunction; Brain energy metabolism; Axon regeneration in the damaged CNS; Pathology of Dementias; Axonal trafficking in neurodegeneration; RNA mediated mechanisms of neurodegeneration; Mitochondrial dynamics, fission, fusion and mitophagy: implications for neuroinflammation; Mitochondrial dysfunction in neurological disease; Molecular Biology of Alzheimer's Disease; Autoimmunity and autoimmune diseases of the CNS; Mouse models of neurodegenerative disease; Fly models; Ips Cells; Prions and neurodegeneration; Optogenetics; Stem cells and neural repair; Epilepsy: EEG; EEG Workshop; EEG imaging; Use of TMS for assessment of motor function; Imaging the normal brain: MRI; Magnetoencephalography; TMS Workshop; fMRI Physics; Quantitative MRI. 
Taking this module as an option?:This module is available as an optional module 
Link to virtual learning environment (registered students only)
Last updated:2018-07-17 15:54:29 by skgtacl