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Information for module BIOL2006

This module is available for 2016/17 and 2017/18 (provisional)

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Module code:BIOL2006 (Add to my personalised list)
Title:Introduction to Human Genetics
Credit value:.5
Division:Division of Biosciences
Module organiser (provisional):DR NIKOLAS MANIATIS
Organiser's location:Biological Sciences
Available for students in Year(s):2
Module prerequisites:BIOL1005 "Introduction to Genetics" or MBBS "Reproduction, Development and Genetics"  
Module outline:This course introduces the subject of human genetics, to enable students to appreciate the implications of genetic research for society and also to provide a basis for more advanced studies. The unifying topic of this course is how genes and their interactions, either with other genes or with the environment, make us what we are. When these interactions break down genetic disease may result, and it is often through these genetic mistakes that we are able to work out what happens in the normal situation. First comes a reminder that Mendelian rules of inheritance can be applied to human families but that this is not always straightforward to interpret. Not all traits are inherited in a simple Mendelian fashion and the methods by which quantitative and multifactorial traits are studied are introduced. These methods are followed by a section on molecular genetics which continues into genetic mapping techniques which culminated in the multi billion dollar human genome project. Within this section we examine some of the better known human genetic diseases which are interesting both for their own sake but also as examples of the results obtained using the molecular methods discussed earlier. One week is spent considering chromosomes. The human genome project has now moved on from the study of �the� human DNA sequence to the study of variation between individuals and populations. The existence of genetic variation, polymorphism, has been known for many years and we look at this both from a historical perspective as well as considering how this is of interest to medicine and to the pharmaceutical industry. The fourth week of the course considers the nature and origin of genetic variation and gives a historical outline of the human genome project. In the fifth week we consider cancer, the biggest problem of genetic disease and finally we look at the study of human populations. 
Module aims:This course aims to introduce the students to the subject of human genetics, to enable them to appreciate the implications of genetic research for society and also to provide a basis for more advanced studies. 
Module objectives:To understand the genetic make-up of humans and the genetic basis of variation at the level of the individual, the family and the population. To understand the significance and nature of genetic disease, and the possibilities for its diagnosis and prevention. Students should be able to understand and critically evaluate scientific studies in human genetics, whether reported in scientific journals or in the lay press. They should be familiar with the human genome project, its general approach, its goals and its achievements. 
Key skills provided by module: 
Module timetable: 
Module assessment:Two invigilated moodle quizzes 30.00%
Unseen two-hour written examination 70.00% 
Notes:The tutorials are an essential (compulsory) component of the course. These classes will include a practical problem booklet in biochemical genetics and one in human chromosome analysis, problems related to lectures, pedigree analysis and the evaluation of data. PLEASE NOTE TIMETABLE CHANGE. From 2017/18 the timetable will change to 11am-1pm on Tuesday and 3pm-5pm on Thursdays. The change will be reflected in the online timetable during the summer.  
Taking this module as an option?: 
Link to virtual learning environment (registered students only) 
Last updated:2017-06-12 10:11:57 by ucbtksr