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Information for module BIOL2004

This module is available for 2017/18

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Module code:BIOL2004 (Add to my personalised list)
Title:Fundamentals of Molecular Biology
Credit value:.5
Division:Division of Biosciences
Module organiser (provisional):Professor Christopher Thompson
Organiser's location:Biological Sciences
Available for students in Year(s):2
Module prerequisites:None 
Module outline:Introduction to DNA. Structure of DNA. DNA as the genetic material. Gene structure and expression. DNA isolation. Restriction / modification enzymes used in molecular biology (ligase, polymerase, kinase, phosphatases, nucleases). DNA analysis. Gel electrophoresis / blotting / labelling DNA. DNA sequencing. Polymerase chain reaction. Cloning vectors. Plasmids, M13, lambda. Applications of DNA technology. A basic introduction to the use of DNA technology in biological research, biotechnology and medicine. eg in situ hybridization, transgenic organisms and production of recombinant proteins; molecular evolution; DNA fingerprinting; functional genomics; the new ‘whole genome’ sequencing technologies; molecular diagnosis of infection / contamination; ancient DNA; phylogenetics.  
Module aims:To give a broad understanding of the principles and applications of modern molecular biological techniques. 
Module objectives:Students will be given the opportunity to learn about: - the structure and properties of DNA, with an emphasis on the practical aspects of DNA manipulation. - DNA as the genetic material. - the properties of the enzymes used in in vitro DNA manipulation. - the properties of cloning vectors and the principles of gene library construction. - the basic techniques of molecular biology: electrophoresis, blotting, sequencing, cloning and the polymerase chain reaction. The practicals will give "hands-on" experience of these techniques. - a range of current applications of DNA technology, to illustrate how the techniques can be applied in very diverse areas of biology, biotechnology, ecology, evolution and medicine.  
Key skills provided by module:Molecular Biology techniques. 
Module timetable: 
Module assessment:Unseen two-hour written examination 70.00%
Coursework 30.00% 
Notes:You are expected to attend the practicals and tutorials, and to complete the coursework. Failure to do so without adequate excuse may result in you failing the course, regardless of how well you do in the exam.  
Taking this module as an option?: 
Link to virtual learning environment (registered students only) 
Last updated:2017-09-07 09:38:57 by ucbtksr