Antibodies and DNA constructs produced by the laboratory are available to the wider research community.
To request these reagents, please contact Alyce McClellan and provide a description of your intended use for them, along with a courier account number to cover shipping costs.
Certain antibodies and hybridomas are also available commercially.
Antibodies
Purified antibodies are also available for purchase from the companies listed below, who have licensed their distribution from the University of California and from Beckton Dickinson where they were produced.
Information for obtaining these antibodies, as well as their specificity and activities, can be obtained from these companies. Literature citations are included for your reference.
| Protein Target | Clone | Vendor | Catalogue no. | Reference |
|---|---|---|---|---|
| Alpha-Adaptin (AP2 adaptor complex) | AP.6 | ThermoFisher Sc. | MA1-064 | PNAS (1989) 86:9289-9293 |
| CLCa/b (Clathrin light chain a and b) - consensus region | CON.1 | BioLegend | MMS-423P | Cell (1992) 68:899-910 |
| CHC17 (Clathrin heavy chain 17) - terminal domain | TD.1 | BioLegend | MMS-427P | Cell (1992) 68:899-910 |
| CHC17 (Clathrin heavy chain 17) - hub region | X22 | ThermoFisher Sc. | MA1-065 | J.Cell.Biol. (1985) 101:2047-2054 |
Hybridomas
Hybridomas for monoclonal antibodies against the clathrin or adaptor proteins listed below are available from the ATCC. Literature citations are included for your reference.
| Protein Target | Clone | Vendor | Catalogue no. | Reference |
|---|---|---|---|---|
| Alpha-Adaptin (AP2 adaptor complex) | AP.6 | ATCC | CRL-2227 | PNAS (1989) 86:9289-9293 |
| CLCa/b (Clathrin light chain a and b) - consensus region | CON.1 | ATCC | CRL-2229 | J.Mol.Biol. (1983) 167:197-204 |
| CLCa (Clathrin light chain a) | CVC.1 | ATCC | TIB-135 | J.Mol.Biol. (1983) 167:197-204 |
| CLCa (Clathrin light chain a) | CVC.7 | ATCC | TIB-138 | J.Mol.Biol. (1983) 167:197-204 |
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Tel: 020 3549 5880
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Frances Brodsky is an established member of the global cell biology community with research connections in immunology, genetics and structural biology from an interdisciplinary and international career.
Read more about Frances Brodsky
Lab Members
Research for Non-Scientists
Project #1 - CHC22 dependent trafficking of the insulin-sensitive GLUT4 glucose transporter
Project #2 - Physiological functions of the clathrin light chains
