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Computational Methods

Links to downloadable software and datasets developed and maintained by the UCL Genetics Institute.

Garrett Hellenthal Group 

 

Sourcefind Hellenthal Lab

ChromoPainterv2: inferring haplotype sharing among individuals  


Download Software

Paper: Inference of Population Structure using Dense Haplotype Data

fineSTRUCTURE: clustering individuals based on haplotype sharing 

Download Software

Paper: Inference of Population Structure using Dense Haplotype Data

SOURCEFIND: inferring proportions of recent ancestry sharing among individuals/groups 

Download Software

Paper: Latin Americans show wide-spread Converso ancestry and imprint of local Native ancestry on physical appearance

GLOBETROTTER: identifying/dating/describing admixture events in a target population 

Download Software

Paper: A Genetic Atlas of Human Admixture History

Dave Curtis Group

plot_of_first_and_second_principal_components_against_self-declared_ancestry

Software and scripts to analyse relationship between genetic variants and complex disease phenotypes, especially utilising sequence data

  • Recent software and scripts
     
  • Older software
     
  • Paper: Multiple linear regression allows weighted burden analysis of rare coding variants in an ethnically heterogeneous population

Richard Mott Group

arabidopsis_magic

 

Genotype Encryption

  • Download Software
     
  • Paper: Private Genomes and Public SNPs: Homomorphic Encryption of Genotypes and Phenotypes for Shared Quantitative Genetics
     
  • Try to crack the encryption and win $1000

Imputation methods for low coverage sequencing

  • Haplotype mosaic reconstruction for MAGIC populations
     
  • See also STITCH (lead: Robert W Davies, Oxford)

Software for Analysing Multiparental populations 

  • HAPPY software for QTL mapping

Genotypes and Phenotypes for Arabidopsis and Wheat MAGIC populations

  • Download Software

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