The anatomy of our eyes and the process of vision is very complicated and delicate. Our vision is determined by the precise anatomy of our eyes and the various cellular processes which occur within. Any kind of disruption to this machinery can cause devasting affects to our vision. In particular, bestrophinopathies target the pigmented layer of the light sensitive part of the eye, the retinal pigment epithelium, which leads to this layer not working correctly and affects the visual pathway, eventually leading to gradual visual loss. You can learn more about the anatomy of the eye, the retinal pigment epithelium and how bestrophinopathies compromise the retinal pigment epithelium by the clicking on the images below.