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UCL IoO at ARVO 2025

7 April 2025

We are sharing a list of planned talks and poster presentations by our institute's staff and early career researchers, including Honorary staff, at ARVO 2025, held in Salt Lake City, Utah from 4 to 8 May.

ARVO design

The theme of the 2025 Annual Meeting addresses how vision research is continually being transformed by new information and technologies. Some of the researchers at our institute (listed below) will showcase their new research and will have the opportunity to network with colleagues and industry thought-leaders.

For the full programme of talks and presentations during the conference, please visit the link provided at the bottom of this page. 

Saturday 3 May
Poster session: Imaging in the Eye

  • Justin Engelmann: RETSeg: Retinal foundation models can do segmentation with a single point

  • Shuo Chen: Automated Retinal Layer and Fluid Segmentation and Cross-sectional Analysis using Spectral Domain Optical Coherence Tomography Images for Diabetic Retinopathy (co-author: Professor Marinko Sarunic)

  • Da Ma: AI-assistant Ocular Imaging Biomarkers of Retinal Cytotoxicity, Glaucoma, and Treatment Monitoring (co-author: Professor Marinko Sarunic)

Sunday 4 May 
3:15-5pm

  • Paper Session 
    Ryan MacDonald: Muller glia regulate retinoic acid signalling in the developing retina to specialise photoreceptors for high acuity vision 
  • Poster session: Ocular disease pathways and biomarkers
    Siyin Liu: Allelic Structure and Somatic Instability Dynamics of CTG18.1 in Fuchs Endothelial Corneal Dystrophy 
  • Poster session: Using multi-omics to understand complex ocular disease
    Richie Hu: Association of Polygenic Risk Scores with Selective Laser Trabeculoplasty Outcomes in the LiGHT Trial
  • Anne-Marie Kladny: Characterizing the extracellular landscape of Fuchs endothelial corneal dystrophy

Monday 5 May
8:30-10:15am
Poster sessions:

  • Charmaine Sim: Initial results from whole genome sequencing from an adult retina clinic serving a multi-ethnic population
  • Asha Vanzara: Comparison of retinal disease genes covered in two comprehensive genetic testing panels and an online resource
  • Marcos Abreu Costa: Implementing a gene burden approach in a genetically refined Fuchs’ endothelial corneal dystrophy patient cohort identifies rare microRNA variants as a novel genetic cause of disease.

Tuesday 6 May
1:15-3pm
Session Title: Moving beyond association: Innovations in functional interpretation of genetic variants 
Session Type: Cross-sectional Group Session 

Presentation:

  • Alice Davidson: Insights into corneal specific repeat instability mechanisms underlying Fuchs endothelial corneal dystrophy 
  • Joanna Shuhan Li: Evaluation of a Novel Artificial Intelligence Model for Evaluating a Cataract Surgery Video Dataset (co-author: Professor Marinko Sarunic)

Wednesday 7 May
10:15am-12pm 
Poster sessions:

  • Vishanna Balbirsingh: Visual acuities in a cohort of patients with CNGA1-associated retinitis pigmentosa
  • Julio Corral Serrano: A novel recurrent ARL3 variant c.209G>A p.(Gly70Glu) causes variable non-syndromic dominant retinal dystrophy with defective lipidated protein transport in human retinal stem cell models.
  • Isabel Walters: Dopamine agonism regulates the nuclear translocation of the transcription co-activator YAP in pediatric, but not adult, human scleral fibroblasts

Paper sessions, 2-3:45pm  (Ballroom J)
Electroretinography: basic mechanisms and disease
Session co-chair: Omar Mahroo

  • 2:15-2:30pm: Justin Engelmann, RETFound-Mobile: Running a high-performance retinal foundation model on a regular smartphone 
  • 2:45-3pm: Sadat Yazdouni: Rod-isolated electroretinogram a-waves in KCNV2-retinopathy compared with a large reference cohort: evidence for loss of an early negative transient
  • 2:45-3pm: Quang Nguyen: Advancing Question-Answering in Ophthalmology with Retrieval-Augmented Generation (RAG): Benchmarking Open-source and Proprietary Large Language Models 

Thursday 8 May
Poster session: AI in Retina III 
8-9:45am

  • David Merle: AI-Driven Analysis of OCT-Biomarkers to Predict Fellow-Eye Conversion in Neovascular AMD: Insights from a Large Real-World Dataset 
  • Mahnoor Malik: Long-flash electroretinograms recorded with a portable system for rapid diagnosis in patients with selective ON-bipolar cell impairment
  • Krishnika Vetrivel: Relative contributions of genetic and environmental factors to variance in photopic flash electroretinogram i-waves explored in a study of over 200 adult twins

11:45am-1:30pm

  • Mark Hughes: Sex distributions in the commonest autosomal genetic causes of retinitis pigmentosa
  • Vijay K Tailor-Hamblin: Visual crowding is elevated in the fovea in CRB1-associated retinopathies 

3-3:15pm

  • Matteo Rizzi: Multi-omic investigation of ABCA4 in rod vs cone photoreceptors
  • Nora Kvam: A Deep Learning Approach for Retinal Pathology Detection in Patients on Long-Term Hydroxychloroquine (co-author: Professor Marinko Sarunic)

Links

Image

  • ARVO 2025 Design