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UCL IoO is recruiting: 2 x Research Fellows for SARKS

22 May 2020

Two new research fellow posts are available to join a new research team (SARKS – Starting a Resource for Keeping Sight), developing a cell-based model of age-related macular degeneration (AMD). Apply by 17 July.

Pipette with test tubes

Job details

We are looking for two postdoctoral researchers to work as part of an exciting new research team (SARKS – Starting a Resource for Keeping Sight) to develop a cell-based model of age-related macular degeneration (AMD):

Post 1 (Ref: 1861374)

Duties and Responsibilities

The successful applicant will work between the Eden and Carr labs to develop iPSC-RPE models of AMD and explore lipid clearance mechanisms from the RPE. The role will involve culturing gene edited and patient-derived iPSC-RPE lines, isolation of photoreceptor outer segments and the use of confocal and electron microscopy to study lipid accumulation.

The appointed post-doc will work with researchers at the UCL Institute of Ophthalmology (Amanda Carr, Emily Eden, Clare Futter, Pete Coffey) and clinicians and researchers at Moorfields Eye Hospital (John Marshall, Alan Bird, Ali Hussein).

The position is funded by a Moorfields Eye Charity philanthropic donation for a period of 2 years in the first instance.

Key Requirements

Essential requirements include a BSc, PhD, molecular and cell biology and microscopy experience. Candidates should also have strong retinal cell biology and membrane traffic knowledge and track record, and experience of high-quality research.

Closing Date: 17 July 2020, 11.59 pm
Interview date: tbc

Find out more and apply via UCL Jobs


Post 2 (Ref: 1861427)

Duties and Responsibilities

The post would suit an ambitious post-doctoral researcher with a strong background and interest in using pluripotent stem cells to model disease. The successful applicant will work with Dr. Amanda Carr and Prof. Pete Coffey to establish an induced pluripotent stem cell hub that will be used to explore early AMD disease mechanisms in retinal pigment epithelium cells, including ageing, stress and wound healing.

The appointed post-doc will work with researchers at the UCL Institute of Ophthalmology (Amanda Carr, Emily Eden, Clare Futter, Pete Coffey) and clinicians and researchers at Moorfields Eye Hospital (John Marshall, Alan Bird, Ali Hussein).

The position is funded by a Moorfields Eye Charity philanthropic donation for a period of 2 years in the first instance.

Key Requirements

Essential requirements include a PhD in a relevant subject, experience working with pluripotent stem cells and a strong molecular and cell biology background. A record of disease modelling using induced pluripotent stem cells is desirable. Candidates should also have excellent communications skills, work well as an effective member of a team, have knowledge of retinal cell biology, degenerative disease modelling and/or ageing and a track record and experience of high-quality research.

Closing Date: 17 July 2020, 11.59 pm
Interview date: TBC

Find out more and apply via UCL Jobs


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