
The process of neurodegeneration is implicated in several degenerative diseases of the retina. These include glaucoma, age-related macular degeneration and some inherited retinal disorders.
The group's work is focused on mechanisms of neurodegeneration and subsequent loss of vision, particularly the early diagnosis and management of age-related neurodegenerative processes.
Aims
- Identify early markers of cell processes in neurodegenerative disease in the eye - including Glaucoma, Alzheimer's, Parkinson's Diseases
- Establish new methods of early diagnosis and treatment of these diseases - using the eye as a window on to the brain
- Develop non-invasive screening and monitoring of neurodegeneration
- Investigate Neuroprotection and rescue modalities
- Assess novel delivery methods of diagnostic and therapeutic agents - in the eye and in the brain
These are to be achieved using novel non-invasive techniques to assess structural and functional changes in different models of disease and their treatment, with a view to offering quick and effective translation to the clinical arena.
Current work
- DARC (Detection of Apoptosing Retinal Cells)
- Glaucoma treatment
- Neurodegeneration
- Optic nerve regeneration
People
- Professor M Francesca Cordeiro - Head of GroupUCL Professor of Retinal Neurodegeneration & Glaucoma Studies & Honorary Consultant Western Eye Hospital, London.
- Dr Li Guo
- Mr Vy Luong
- Dr Tim Yap
- Dr Shiama Balendra
- Dr Sotaro Mori
- Miss Soyoung Choi
- Mr Daniel Hill
Alumni
- Ms Cinzia Mazzei - Former Research Fellow
- Mr Nicholas Wood - Former Research Assistant/Technician
- Ms Sarah Borrie - Former Research Assistant/Technician
- Dr Annelie Maass - Former PhD Student
- Dr Guilio Ferrari - Clinical Research Fellow
- Dr Steffen Schmitz Valckenberg - Clinical Research Fellow
- Mr Jonathan Brenton - Former MSc student
- Dr Milena Pahlitzsch - Clinical Research Fellow
- Dr Fatimah Javaid - Clinical Research Fellow
- Dr Parth Shah -Former MSc Student
- Ms Shereen Nizari
- Dr Lisa Turner
- Dr Mark Tilley
- Dr Valeria Bono
- Dr Giulia Malaguarnera
- Dr Gaia Pollorsi
- Dr Mohammad Dehabadi
Collaborators
- Satyanarayana Somavarapu
- Stephen Moss
- Fred Fitzke
- Steve Dakin
- Matteo Carandini
- Frances Edwardes
- Michel Duchen
- Dr John Maddison
- Prof Richard Nicholas
- Dr Eduardo Normando
- Dr Mariya Hristova
- Dr Jennifer Sun

