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UCL Institute of Ophthalmology

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Glaucoma and Retinal Neurodegenerative Disease Research Group

The process of neurodegeneration is implicated in several degenerative diseases of the retina. These include glaucoma, age-related macular degeneration and some inherited retinal disorders.

Group's work is focused on mechanisms of neurodegeneration and subsequent loss of vision, particularly the early diagnosis and management of age-related neurodegenerative processes.

Aims

  1. Identify early markers of cell processes in neurodegenerative disease in the eye - including Glaucoma, Alzheimer's, Parkinson's Diseases
  2. Establish new methods of early diagnosis and treatment of these diseases - using the eye as a window on to the brain
  3. Develop non-invasive screening and monitoring of neurodegeneration
  4. Investigate Neuroprotection and rescue modalities
  5. Assess novel delivery methods of diagnostic and therapeutic agents - in the eye and in the brain

These are to be achieved using novel non-invasive techniques to assess structural and functional changes in different models of disease and their treatment, with a view to offering quick and effective translation to the clinical arena.

News

Collaborations

DARC Phase I Clinical Trial for Early Diagnosis of Neurodegeneration

DARC Phase II Clinical Trial

Eye Drops for Macular Degeneration (ED4MD)

Parkinson's

Other Projects

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Awards

Recent Publications

Funding