UCL Institute of Ophthalmology


Glaucoma and Retinal Neurodegenerative Disease Research Group



The process of neurodegeneration is implicated in several degenerative diseases of the retina. These include glaucoma, age-related macular degeneration and some inherited retinal disorders.

The group's work is focused on mechanisms of neurodegeneration and subsequent loss of vision, particularly the early diagnosis and management of age-related neurodegenerative processes.


  1. Identify early markers of cell processes in neurodegenerative disease in the eye - including Glaucoma, Alzheimer's, Parkinson's Diseases
  2. Establish new methods of early diagnosis and treatment of these diseases - using the eye as a window on to the brain
  3. Develop non-invasive screening and monitoring of neurodegeneration
  4. Investigate Neuroprotection and rescue modalities
  5. Assess novel delivery methods of diagnostic and therapeutic agents - in the eye and in the brain

These are to be achieved using novel non-invasive techniques to assess structural and functional changes in different models of disease and their treatment, with a view to offering quick and effective translation to the clinical arena.