EyeTherapy Blog News
UCL Gene Therapy Trial shows Benefit for up to Three Years After Treatment
Tue, 05 May 2015 14:44:39 +0000
We are delighted to be able to announce that yesterday, Monday 4th May, the long-term results of our RPE65 gene therapy trial for Leber Congenital Amaurosis Type 2 (LCA2) were published in the prestigious New England Journal of Medicine. Begun in 2007, this was the world’s first-in-human trial of gene therapy to treat an inherited […]Read more...
UCL researchers solve a major riddle of retinal degeneration research!
Mon, 26 Jan 2015 10:11:36 +0000
Today a paper published in Nature Communications from the Gene and Cell Therapy Group at the UCL Institute of Ophthalmology has shed light on why, until now, it has not been possible to effectively restore vision in rd1 mice – the world’s major model for retinitis pigmentosa (RP). The rd1 mouse is a model of […]Read more...
Professor Ali honoured for his contribution to research into retinal disease
Mon, 08 Sep 2014 12:27:36 +0000
Professor Robin Ali, PhD, Professor of Human Molecular Genetics and Head of the Department of Genetics, UCL Institute of Opthalmology has been awarded the Pioneer Award for his work in proof-of-concept studies that have demonstrated the feasibility of using gene therapy and cell transplantation to treat dysfunction and degeneration of the cells […]Read more...
Prizes and awards
The Gene and Cell Therapy Group is proud to announce the following awards and prizes:
Peter Gardner and Andrew Dick were awarded by Fight for Sight the Dr Hans and Mrs Gertrude Hirsch small grant award to the amount of £15,000 for their work on the 'Investigation of Annexin-A1 Expression in Healthy and Uveitis Ocular Tissue'.
Anai Gonzalez-Cordero received a £200 prise for her public division category entry to the BBSRC Images with Impact competition entitled:
Robin Ali was awarded the Pioneer Award by the journal of Human Gene Therapy in recognition of the proof-of-concept studies he has led which have demonstrated the feasibility of using gene therapy to repair photoreceptor defects in the eye and of using cell transplantation for retinal repair as well as his pioneering role in the first clinical trial for inherited retinal degeneration.
Anai Gonzalez-Cordero received a £750 purse and the 13th annual Ruskell Medal from The Worshipful Company of Spectacle Makers for the contribution made to the advancement of ophthalmology and visual sciences in her 2013 Nature Biotechnology paper entitled:
- Photoreceptor Precursors derived from three-dimensional embryonic stem cell cultures integrate and mature within adult retina
Anna Graca received a £681 Travel Grant from Guarantors of Brain to attend the XVIth International Symposium on Retinal Degenerations (RD2014) - July 13 to 18 in Pacific Grove CA, USA in recognition of her accepted abstract entitled:
- Comparative assessment of gliosis and associated changes in the extracellular matrix in murine models of retinal degeneration
Anna Graca received a £400 Travel Grant from the Biochemical Society to attend the XVIth International Symposium on Retinal Degenerations (RD2014) - July 13 to 18 in Pacific Grove CA, USA in recognition of her accepted abstract entitled:
- Comparative assessment of gliosis and associated changes in the extracellular matrix in murine models of retinal degeneration
Martha Robertson received a grant from the Convergent Science Network for Biomimetics and Neurotechnology (CSNII) to cover her placement on the Okinawa Institute of Science and Technology Compuational Neuroscience Course (OCNC2014).
Rachel Pearson received an Alcon Research Institute Young Investigator Award which includes $50,000 in recognition of her outstanding work in ophthalmic research and to support her continued work into photoreceptor replacement therapy for the treatment of retinal degeneration.
Claire Hippert was awarded a $1,675 Travel Fellowship and complementary registration from the XVIth International Symposium on Retinal Degenerations (RD2014) - July 13 to 18 in Pacific Grove CA, USA in recognition of her accepted abstract entitled:
- Modulation of gliosis using shGFAP and shVimentin to determine its role in photoreceptor transplantation efficiency
Colin Chu was awarded a $1,100 InternationalTravel Grant and complementary registration from the Association for Research in Vision and Ophthalmology (ARVO) to attend ARVO 2014 - May 4 to 8 in Orlando FL, USA in recognition of his accepted abstract entitled:
- Peripheral vasculitis, ischemia and vascular leakage in uveitis as evaluated by ultra widefield fluorescein angiography
Jonathan Aboshiha was awarded a $1,100 InternationTravel Grant and complementary registration to attend ARVO 2014 - May 4 to 8 in Orlando FL, USA from the National Institute for Health Research Biomedical Research Centre at Moorefields Eye Hospital NHS Trust in recognition of his accepted abstract entitled:
- Relative preservation of foveal outer retinal structure in infants with AIPL1 associated Leber's Congenital Amaurosis: implications for gene therapy
Philipp Herrmann was awarded a £681Travel Award to attend ARVO 2013 - May 5 to 9 in Seattle WA, USA from University College London in recognition of his accepted abstract entitled:
- CD59a deficiency leads to increased age-related subretinal macrophage accumulation and elevated local C3 expression in the RPE/choroid complex of aged mice (web page)
Colin Chu was awarded a £681Travel Award to attend ARVO 2013 - May 5 to 9 in Seattle WA, USA from University College London in recognition of his accepted abstract entitled:
- An optical coherence tomography based in vivo scoring system for experimental autoimmune uveoretinitis (web page)
Ulrich Luhmann was awarded the Retina Suisse Award 2012 in the category “Young Researcher” for the best talk at the Swiss Eye Research Meeting 2012, Bienne, Switzerland
Clemens Lange was awarded the Moorfields Eye Hospital Research Medal and the Edith von Kaula Young Investigator Research
Award from the University of Freiburg
James Bainbridge was awarded an NIHR Research Professorship.
Rachael Pearson was awarded the the European Society for Gene and Cell Therapy (ESGCT) Young Investigator award.
Ulrich Luhmann was awarded an ISER Travel Fellowship to support his attendance at the XX Biennial Meeting of the International Society for Eye Research. He was also awarded a Travel Fellowship to support his attendance at the XVth International Symposium on Retinal Degeneration (RD2012). Both meetings were held in Germany in July 2012.
Daniel Kampik and Clemens Lange were awarded ARVO International Travel Grants of US$1100 to support their visit to Fort Lauderdale for the ARVO 2012 annual conference.
Tassos Georgiadis was elected to the British Society of Gene Therapy board.
Kam Balaggan won the Fould's Trophy for the best Free Paper presentation at the Royal College of Ophthalmologists, Birmingham 2012.
Clemens Lange was awarded a travel grant to attend the ARVO 2011
conference by the UCL Graduate School.
Claire Hippert was awarded EUR250, sponsored by Sangamo, for submitting one of the top scoring abstracts for the ESGCT & BSGT 2011 joint meeting.
Scott Robbie, Mark Basche, Amanda Barber and Anastasios Georgiadis were awarded ARVO International Travel Grants of US$1100 to support their visit to Fort Lauderdale for the ARVO 2011 annual conference.
We would like to thank the following organisations for the support awarded during 2011: The Special Trustees of Moorfields Eye Hospital, The BBSRC, National Institute for Health Research BMRC for Ophthalmology, Medical Research Council and RP Fighting Blindness.
Prof. Robin Ali was awarded the ARVO/Pfizer
Ophthalmics/Carl Camras Translational Research Award at the ARVO 2010
annual meeting in Fort Lauderdale.
Clemens Lange received a highly commended award for his work on "Oxygen distribution and molecular mediators in proliferative diabetic retinopathy" at the NIHRBiomedical Research Centre Experimental Medicine Summer School in June 2010.
Clemens also received a runners-up award for his poster on "Von Hippel-Lindau expression in the retinal pigment epithelium is essential for normal eye development and vascular homeostasis" at the UCL Institute of Ophthalmology postgradute poster session and a UCL student conference fund travel award to support his visit to Fort Lauderdale for the ARVO 2010 annual conference.
Our Experimental Eye Research article Pharmacological disruption of the outer limiting membrane leads to increased retinal integration of transplanted photoreceptor precursors, West et al. 2008 was the "Top cited Article 2008-2010”
Ulrich Luhmann was awarded a $1057 RD2010 Young Investigators Award to attend the International Symposium on Retinal Degeneration to be held in Quebec, Canada in July 2010.
Emma West and Kate Warre Cornish were each awarded an ARVO International Travel Grant of US$1100 to support their visit to Fort Lauderdale for the ARVO 2010 annual conference.
We would like to thank the following organisations for the support awarded during 2010: Special Trustees Moorfields Eye Hospital, Oxford Biomedica, GlaxoSmithKlein, National Institute for Health Research BMRC for Ophthalmology, The BRPS and Fight For Sight
Livia Carvalho, Anastasios Georgiadis, Ulrich Luhmann, Marija Mihelec and
Scott Robbie were each awarded travel grants to attend the ARVO 2009 conference
by the UCL Graduate School. Susie Barker was also successful in her application
for a Research Project Funds grant.
Prof. Robin Ali won an Alcon Research Institute Award for his outstanding contribution to advancing eye health.
Mr. James Bainbridge was awarded The Fincham Medal by the The Worshipful Company of Spectacle Makers. This award is given to those who, whilst still in mid-career, are deemed to have made an outstanding contribution to the advancement of visual science.
Prof. Robin Ali and Mr. James Bainbridge won a Foundation Fighting Blindness (FFB) Board of Directors Award at the Day of Science Conference for his outstanding achievements.
The European Uveitis Patient Interest Association awarded Peter Trittibach 3rd prize in the field of 'Experimental Uveitis' for his paper Lentiviral-vector mediated expression of murine IL-1 receptor antagonist or IL-10 reduces the severity of endotoxin-induced uveitis. P Trittibach, SE Barker, CA Broderick, M Natkunaraja, Y Duran, SJ Robbie, JWB Bainbridge, G-M Sarra, AD Dick and RR Ali Gene Ther.2008; 15 (22): 1478-88.
Anastasios Georgiadis won a runner-up prize in the UCL Graduate School Research Poster Competition 2009 Biomedical and Life Sciences category for his poster on AAV-mediated shRNA and miRNA silencing of a photoreceptor gene in vivo.
Prof. Ali was awarded National Institute of Health Research (NIHR) Senior Investigator status in recognition of his contribution to research and research leadership.
Kam Balaggan came 1st runner up for the Allergan Research Fellowship award for the presentation: "Looking Beyond Anti-VEGF Pharmacotherapy: The Genetic Targeting of Aberrant Choroidal Neovascularisation".
We would like to thank the following organisations for the support awarded during 2009: The Wellcome Trust, The Royal Society and The BRPS
Rachael Pearson was awarded £5000 by Fight for Sight and the Royal College
of Ophthalmologists. The prize is awarded to young ophthalmologists and
scientists (under 40) working in the field of ophthalmology in recognition of
the completion of a significant piece of research in an area that falls within
the remit of the charity.
Mei Hong Tan was runner-up in the oral plenary presentation at the Medical Research Society Academic Meeting 2008 and was also awarded a Pushpa Chopra Travel Award.
Our Stem Cell group won the Poster Prize at the MRC Showcase Meeting in Bristol.
Rachael Pearson and Ulrich Luhmann were each awarded an ARVO International Travel Grant of US$1000 to support their visit to Fort Lauderdale for the 2008 annual conference.
We would like to thank the following organisations for the support awarded during 2008: The Medical Research Council, European Union and National Institute for Health Research BMRC for Ophthalmology
Prof. Robin Ali was elected Fellow of the Academy of Medical Sciences
Kam Balaggan was the winner of the Moorfield's Research Medal (Arthur Stelle Medal) 2007.
Prateek Buch was awarded a UCL Graduate School Travel award (£250) to support his attendance at the Society for Neuroscience Conference in November 2007
We would like to thank the following organisations for the support awarded during 2007: The Medical Research Council, The Wellcome Trust, The Royal Society, Fighting Blindness Ireland, The Royal College of Surgeons of Edinburgh, The BBSRC and The BRPS.
Page last modified on 19 dec 14 15:45