IoO Seminar Series with Greg Field

Greg Field

Associate Professor-in-residence, Ophthalmology at University of California, Los Angeles

Greg Field
Associate Professor-in-residence, Ophthalmology at the University of California, Los Angeles
 
Dr. Greg Field leads the Retinal Circuits Lab at UCLA’s Jules Stein Eye Institute, where his team explores the retina’s ability to process visual information and transmit it to the brain. By integrating multi-electrode arrays (MEA), genetic tools, and computational approaches, his research seeks to uncover how neuronal circuits in the retina work in health and adapt to retinal degenerative conditions such as glaucoma and age-related macular degeneration (AMD). The lab also investigates how theoretical frameworks, like efficient coding theory, can explain the diversity of retinal cell types, bridging mathematical models with experimental neurobiology. Dr. Field’s work aims to address fundamental questions in vision science, such as how the retina encodes complex scenes and adapts to low-light conditions, and how these principles can be leveraged for novel treatments to restore vision in degenerative diseases.

Selected Publications

• Roy S, Yao X, Rathinavelu J, Field GD. GABAergic Inhibition Controls Receptive Field Size, Sensitivity, and Contrast Preference of Direction Selective Retinal Ganglion Cells Near the Threshold of Vision. J Neurosci. 2024.
• Scalabrino ML, Thapa M, Wang T, Sampath AP, Chen J, Field GD. Late gene therapy limits the restoration of retinal function in a mouse model of retinitis pigmentosa. Nat Commun. 2023.
• Scalabrino ML, Thapa M, Chew LA, Zhang E, Xu J, Sampath AP, Chen J, Field GD. Robust cone-mediated signaling persists late into rod photoreceptor degeneration. Elife. 2022.

Join us to hear Dr Field discuss how efficient coding theory contributes to understanding the diversity of retinal cell types and the implications for vision science and potential therapies.