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UCL Queen Square Institute of Neurology

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Anna Kuppuswamy

Anna Kuppuswamy

Post-Doctoral Research Fellow

I am a physiotherapist and a neuroscientist. I am interested in studying movement, especially how the brain controls movement, what goes wrong in the brain when someone looses the ability to move and how we can restore movement.  

Neurophysiology of Fatigue After Stroke (NeuroFAST)

Currently I am interested in understanding the mechanism of fatigue in stroke patients.

A large proportion of stroke survivors complain they feel “tired”.We know that fatigue is experienced due to a combination of changes in the muscle and in the brain regions that control the muscles. In this study I will be testing the idea that fatigue occurring after stroke is due only to changes within the brain regions controlling the muscles.

I will be studying 142 patients over the next 3 years. I will be recruiting stroke patients who have or had difficulty in moving their limbs to participate in my study. Patients who have had a stroke within the last 3 to 9 months interested in taking part in the study please see the project page or see the Volunteer Advertisment (pdf). 

Selected publications

A model of poststroke fatigue based on sensorimotor deficits.

Kuppuswamy A, Rothwell J, Ward N.

Curr Opin Neurol. 2015 Dec;28(6):582-586.

Limb Heaviness: A Perceptual Phenomenon Associated With Poststroke Fatigue?

Kuppuswamy A, Clark E, Rothwell J, Ward NS.

Neurorehabil Neural Repair. 2015 Jul 17. pii: 1545968315597071. [Epub ahead of print]

Post-stroke fatigue: a problem of altered corticomotor control?

Kuppuswamy A, Clark EV, Sandhu KS, Rothwell JC, Ward NS.

J Neurol Neurosurg Psychiatry. 2015 Aug;86(8):902-4. doi: 10.1136/jnnp-2015-310431. Epub 2015 Apr 17.

Post-stroke fatigue: a deficit in corticomotor excitability?

Kuppuswamy A, Clark EV, Turner IF, Rothwell JC, Ward NS.

Brain. 2015 Jan;138(Pt 1):136-48. doi: 10.1093/brain/awu306. Epub 2014 Nov 2.

Action of 5 Hz repetitive transcranial magnetic stimulation on sensory, motor and autonomic function in human spinal cord injury.

Kuppuswamy A, Balasubramaniam AV, Maksimovic R, Mathias CJ, Gall A, Craggs MD, Ellaway PH. Clin Neurophysiol. 2011 Dec;122(12):2452-61. Epub 2011 May 19.

Cortical control of erector spinae muscles during arm abduction in humans.

Kuppuswamy A, Catley M, King NK, Strutton PH, Davey NJ, Ellaway PH. Gait Posture. 2008 Apr;27(3):478-84. Epub 2007 Jul 17.

Motor neurone excitability in back muscles assessed using mechanically evoked reflexes in spinal cord injured patients.

Kuppuswamy A, Theodorou S, Catley M, Strutton PH, Ellaway PH, McGregor AH, Davey NJ. J Neurol Neurosurg Psychiatry. 2005 Sep;76(9):1259-63.

Education

PhD (2009) - Imperial College London, UK

MSc (2003) - University College London, UK

BPT (Physiotherapy - 2002) - Madras Medical College, India

Funding

2016-2021 - Sir Henry Dale Fellow, Wellcome Trust and Royal Society

2015-2018 - Co-Investigator, Stroke Association project grant, UK

2012-2015 - Senior Research Training Fellowship, The Stroke Association, UK

2010-2011 -  Knowledge Transfer Fellowship, ESRC, UK

2009-2010 - Visiting Fellowship, National Institutes of Health, USA

2006-2009 - PhD, International Spinal Research Trust, UK

2003-2005 - Research Assistantship, International Spinal Research Trust, UK

2002-2003 - HSBC Educational Trust India Fellowship, UK/India

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