XClose

UCL Queen Square Institute of Neurology

Home
Menu

Wilson's disease

A rare autosomal recessive disease characterized by the deposition of copper in the BRAIN; LIVER; CORNEA; and other organs. Clinical features include LIVER CIRRHOSIS; LIVER FAILURE; SPLENOMEGALY; TREMOR; bradykinesia; DYSARTHRIA; CHOREA; MUSCLE RIGIDITY; Kayser-Fleischer rings (pigmented corneal lesions); ATAXIA; and intellectual deterioration. Hepatic dysfunction may precede neurologic dysfunction by several years.

Wilson's disease: information from Patient UK website

Wilson's disease: factsheet from NINDS, the National Institute of Neurological Disorders and Stroke information (US site)

Wilson Disease: information from NORD, the National Organization for Rare Disorders (US site)

PubMed Medline search on Wilson's disease
Medline NLM definition: Wilson's disease is not a MeSH term, but it is associated with the MeSH term Hepatolenticular Degeneration   
 

Support Groups

Wison's Disease Support Group
The Wilson's Disease Support Group UK is an all volunteer organisation which strives to promote the well-being of patients with Wilson's Disease and their families and friends.

Metabolic Support UK
Metabolic Support UK (formerly known as Climb - Children Living with Inherited Metabolic Diseases) are the leading patient organisation for Inherited Metabolic Disorders supporting thousands of patients worldwide.

Brain and Spine Foundation
Information on living with a neurological condition and on diagnosis. There are publications and resources. The useful glossary of neurological conditions (under 'Information and support') includes links to some other organisations as well as to Brain and Spine Foundation information.

Healthtalk: nerves and brain
Personal experiences of people living with various neurological conditions.

Neurological Alliance
Collective voice for 80 organisations, including stroke and brain injury. Organisations are listed at https://www.neural.org.uk/our-members/, a good place to start if looking for information on those conditions. Site also includes information about living with a neurological condition, a glossary, and information about onset and diagnosis as well as a small set of real life stories.

NHS Inform: brain, nerves and spinal cord 
NHS inform is Scotland's national health information service, with the aim of providing the people in Scotland with accurate and relevant information to help them make informed decisions about their own health and the health of the people they care for.

 

disclaimer