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GABA neurotransmitter may be progressive MS marker

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A neurotransmitter widely distributed in the brain may be a marker of a progressive multiple sclerosis, according to research led by Professor Olga Ciccarelli, UCL Institute of Neurology, published in Brain.

Piepenbrock Group and German Center for Neurodegenerative Diseases honour Professor Hardy

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Professor John Hardy - copyright Royal Society

Professor John Hardy, UCL Institute of Neurology, will be awarded this year’s “Hartwig Piepenbrock-DZNE Prize” honouring his seminal contributions to the study of Alzheimer’s disease.

The award ceremony will take place on World Alzheimer's Day, September 21, 2015, in Bonn, Germany.

Professor Hardy has made ground-breaking findings on the molecular causes of this brain disorder. His discoveries provide the basis for therapeutic approaches and potential medicines.

Professor John Hardy - copyright Royal Society

Compensation in Huntington’s disease

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A new measure has been developed which can explicitly characterise compensation in Huntington’s disease (HD) gene-carriers prior to clinical diagnosis. Publishing in EBioMedicine, the research team working on the study hope that identifying patterns of compensation in preclinical HD will not only improve understanding of neural mechanisms underlying HD pathology, but also provide potential targets that can be used in the testing of HD therapeutics.

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