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UCL Queen Square Institute of Neurology

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Brain meeting: Alisa Loosen

15 December 2023, 3:15 pm–4:15 pm

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Decision Making and Uncertainty in Obsessive-Compulsive Disorder

This event is free.

Event Information

Open to

All

Cost

Free

Organiser

Brain Meetings

Location

Seminar Room
12 Queen Square
Queen Square
London
WC1N 3AR
United Kingdom

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Although obsessive-compulsive disorder (OCD) is better understood and more treatable than ever, we still know very little about it. The disorder’s complexity is reflected in inconsistent neuropsychiatric findings that recent computational advances are trying to tackle. In this talk, I will identify three core themes relevant to a computational psychiatry of OCD: information seeking, confidence and cognitive flexibility. I will point out their consistent findings and open questions, which in turn will introduce our most recent research. The uncertainty of the Covid-19 pandemic enabled us to test the ecological validity of prominent lab-based information-seeking findings in OCD. Moreover, using a large-scale longitudinal study, we examined the psychometric quality of the predictive-inference task. This task has led to important, yet inconsistent, confidence findings in the field. Finally, in the last section of this talk, I will introduce our most recent patient-control study in which we aim to capture the link between cognitive flexibility and confidence across groups in an app-based decision-making paradigm.

About the Speaker

Alisa Loosen

at UCL/University of Oxford