Dementia with Lewy bodies has a unique genetic profile, distinct from those of Alzheimer’s disease or Parkinson’s disease, according to the first large-scale genetic study of this common type of dementia which was led by UCL Institute of Neurology.
Publication date: 18 December 2017
at UCL Institute of Neurology have discovered how certain forms of motor neuron disease begin and
progress at cellular and molecular levels, revealing potential new ways
to slow down or even stop this process. The team are already working
closely with pharmaceutical companies to use this knowledge to develop
new treatments for motor neuron disease and other neurodegenerative
Publication date: 2 June 2017
We are delighted to announce that Professor
Mary Reilly is now the first ABN President from 2017-2019. She was President
elect from 2015-2017.
Publication date: 8 May 2017
A team from the Leonard Wolfson Experimental Neurology Centre (LWENC), run jointly by the National Hospital for Neurology and Neurosurgery (NHNN) and UCLInstitute of Neurology, have been awarded the first ever major UK grant to investigate how changes in gut bacteria could slow the progression of neurodegenerative disorders such as Motor Neuron Disease (MND).
Publication date: 28 March 2017
Institute of Neurology team at Red Bull F1 with Sir Jackie Stewart - innovation key in fight against dementia
UCL Institute of Neurology have recently formed a link with Sir Jackie Stewart and his new charity “Race Against Dementia”
Publication date: 17 February 2017
The core mission of UCL Institute of Neurology is to translate discovery science into new diagnostics and ultimately treatments for patients with neurological diseases. Bidirectional patient and public engagement is a central part of this strategy.
Publication date: 16 February 2017
Evidence of chronic traumatic encephalopathy (CTE), a potential cause of dementia caused by repeated blows to the head, has been found in the brains of former association football (soccer) players examined at the Queen Square Brain Bank, UCL Institute of Neurology.
Publication date: 15 February 2017
main changes in our brains as we get older are in the brain
cells with a supporting role, called glial cells, British
scientists have found.
Publication date: 12 January 2017
Launch of the PHAGO project to explore a new approach for patients suffering from Alzheimer’s disease
On 1st November 2016 the Innovative
Medicines Initiative (IMI) together with an association of industrial partners came
together to support PHAGO, an innovative research project devoted to the
development of immunomodulatory therapies for Alzheimer’s disease (AD).
Publication date: 11 January 2017
have moved into the new £650 million Francis Crick Institute building in
and are starting work in their purpose-built labs. Next to St Pancras
and the British Library, the Crick will be the biggest biomedical
under one roof in Europe.
Publication date: 1 September 2016
Dr Tammaryn Lashley, Alzheimer's Research UK Senior Research Fellow, UCL Institute of Neurology, was interviewed on the Victoria Derbyshire show this week, discussing the work of brain banks such as the Queen Square Brain Bank.
Publication date: 3 August 2016
New paper in Neuron highlights importance of slow axonal transport in motor neuron function; implications for neuromuscular diseases
“This excellent work
from Alison Twelvetrees at the Institute of Neurology demonstrates the
importance of slow axonal
transport which is highly relevant to our understanding of motor neuron function and neuromuscular diseases” Gipi Schiavo Wellcome Senior Investigator and Professor of Cellular Neurobiology
Publication date: 20 June 2016
The core mission of the Institute of Neurology is to
translate discovery science into new diagnostics and ultimately treatments for
patients with neurological diseases. Bidirectional patient and public
engagement is a central part of this strategy.
Publication date: 20 June 2016
A new BBC One film examining the science behind dementia, which was partly filmed at the Queen Square Brain Bank and the Leonard Wolfson Experimental Neurology Centre (LWENC), UCL Institute of Neurology, aired last week.
Publication date: 24 May 2016
We are delighted to announce that Jernej Ule, UCL Institute of Neurology, has been elected to EMBO
membership, alongside 57 other outstanding researchers in the life
Publication date: 23 May 2016
Researchers, led by BRC-supported Professor Nicholas Wood, UCL Institute of Neurology, have made a breakthrough in their understanding of Parkinson’s disease after they discovered a chromosome deletion linked to Parkinson’s disease and other genetic disorders.This study analysed multiple datasets, including significant contribution from UKPD study and the IPDGC consortium, both had received funding from The Wellcome Trust/MRC. This study found people with Parkinson’s disease had a piece of DNA missing from chromosome 22q. This particular ‘chromosome deletion’ has up until now normally been associated with DiGeorge syndrome, a genetic disorder usually noticeable at birth that can cause heart defects, problems with the mouth, feeding and hearing, and multiple other diseases.
Publication date: 21 April 2016
Study shows abnormal protein aggregation causes inherited neuropathy: potential new target for therapy
A collaboration between the Medical Research Council (MRC) Centre for Neuromuscular Diseases at UCL Institute of Neurology, the Medical University Vienna and the John P. Hussman Institute for Human Genetics, University of Miami has identified abnormal protein aggregation secondary to mutations in the Neurofilament heavy chain as a cause of autosomal Dominant Charcot Marie Tooth disease type 2 (CMT2).
Publication date: 15 April 2016
Mutations in a gene that helps brain cells communicate with one another can cause chorea in childhood, according to research led by UCL Institute of Neurology, published in the American Journal of Human Genetics.
Publication date: 14 April 2016
A new drug to treat the muscle wasting disease inclusion body myositis (IBM) reverses key symptoms in mice and is safe and well-tolerated in patients, finds a new study led by the Medical Research Council (MRC) Centre for Neuromuscular Diseases at University College London (UCL) Institute of Neurology and the University of Kansas Medical Center.
Publication date: 30 March 2016
Publication date: 10 March 2016
Dr Rita Guerreiro, an Alzheimer's Society senior research
fellow who works at the Department of Molecular Neuroscience at the UCL Institute of Neurology, has been awarded the
prestigious Fondazione Gino Galletti Neuroscience Prize 2015.
Publication date: 11 December 2015
UCL Institute of Neurology Professor John Hardy is first UK winner of $3m Breakthrough Prize in Life Sciences
John Hardy (Department of Molecular Neuroscience, UCL Institute of Neurology) was last night awarded
the $3 million Breakthrough Prize in Life Sciences for his pioneering
into the genetic causes of Alzheimer’s disease, other forms of dementia
Publication date: 9 November 2015
MRC Centre-BRC MRI Biomarker Collaboration in Lancet Neurology: Important implications for experimental trials in Neuromuscular Diseases
A UCL Institute of Neurology study published in Lancet Neurology this week provides important prospective evidence that quantitative MRI can reliably and sensitively track disease progression in Neuromuscular Diseases. The research shows that the MRI biomarkers developed by the MRC Centre team have real potential to become the widely adopted surrogate endpoint in neuromuscular trials.
Publication date: 9 November 2015
Two Motor Neuron Disease (MND) awareness events, co-organised by Dr Rickie Patani, UCL Institute of Neurology, Dr Emma Hodson-Tole, Manchester Metropolitan University (MMU), and Motor Neuron Disease Association (MNDA) were showcased during the recent Manchester Science Festival. Both activities were developed to try and translate to a wide audience the cycle scientific investigation goes through, raising awareness of MND, the MND Association and the research supported by the charity, as well as inspiring the next generation of scientists.
Publication date: 6 November 2015
Professor John Hardy, UCL Institute of Neurology, will be awarded this year’s “Hartwig Piepenbrock-DZNE Prize” honouring his seminal contributions to the study of Alzheimer’s disease.
Publication date: 17 August 2015