UCL Queen Square Institute of Neurology


Prof Janice Holton

Prof Janice Holton, Honorary Consultant and Professor in Neuropathology

Prof Holton participates in the routine work of the Division of Neuropathology reporting neurosurgical specimens as part of a team of 6 Consultant Neuropathologists and has responsibility for the adult muscle biopsy diagnostic service.


Prof Holton is actively engaged in research in the field of inflammatory muscle diseases and has recently written a book chapter on the subject. She is a founder member of the Council of the British Myology Society.


Queen Square Brain Bank

The Queen Square Brain Bank (QSBB) houses one of the largest neurodegenerative brain tissue resources in the UK. This unique collection consists of cases of Parkinson’s disease, hereditary forms of parkinsonism and cases presenting with an atypical parkinsonian syndrome such as progressive supranuclear palsy, corticobasal degeneration and multiple system atrophy. Since 2002 a prospective collection of brain tissue from well-documented early onset and familial dementia cases has been added to the portfolio. Approximately 90 cases are received each year and all are subject to an extensive diagnostic process and a full report is issued by either Dr Holton or Professor Revesz. Following this, cases are made available to researchers for study. Dr Holton is actively involved in neuropathological research in the fields of multiple system atrophy, Parkinson’s disease and dystonia.

National Committees

Prof Holton is an active member of the British Neuropathological Society and has held the offices of Treasurer and Chair of the Education and Meetings Committee. In the latter role she was responsible for the organization of the annual meeting of the Society including the preparation of the scientific programme. She also organized two summer schools on behalf of the Society.


Editorial commitments

Prof Holton has been a member of the editorial board of Neuropathology and Applied Neurobiology, the journal of the British Neuropathological Society since 2006 and has acted as an Executive Editor since January 2012.