- Population Screening for vCJD Using a Novel Blood Test
- Chief Medical Officer appoints Professor Rossor as NIHR National Director for Dementia Research
- New partnership between UCLP brain tumour scientists and Brain Tumour Research
- Professor Hardy awarded Dan David Prize for work on the amyloid gene encoding APP
- NIHR award £650,000 for research into rare neurodegenerative and neuromuscular diseases
- Lowering levels of toxic protein reverses abnormalities in cells from patients with Huntington's disease
- Major initiative in understanding synaptic basis of neuropsychiatric disease
- Visit to the Berlin School of Mind and Brain
- Institute of Neurology ranked as the world’s top institution for epilepsy research.
- Predicting age at onset in SCA1 : does size matter?
- UCL takes the lead with £8.5m funding for dementia research
- Secretary of State visits leading dementia research projects
- Riboflavin Treatment for Childhood onset Motor Neuron Disease
- Dreading pain can be worse than pain itself
- Different gene expression in male and female brains helps explain differences in brain disorders
- New £20m centre pioneers first-in-man trials for neurodegenerative diseases
- RNA build-up linked to dementia and motor neuron disease
- Researchers estimate one in 2,000 people in the UK carry variant CJD proteins
- Professor Alan Thompson discusses Atlas of MS on Lancet News
- Wellcome Trust Principal Fellowship award to explore neural coding with the tripartite synapse
- Marsden's Book of Movement Disorders wins Neurology first prize at the 2013 BMA Book Awards
- Scientists develop refined diagnostic tool for inherited dementias
- Genetic mutations linked to Parkinson's Disease
- P-glycoprotein over-activity and drug resistance in temporal lobe epilepsy
- New Yale-UCL collaboration in brain aneurysm genetics
- ‘Risky’ stroke prevention procedure may be safe in some patients
- The Michael J. Fox Foundation awards grant for Exenatide research
- Institute Professor leads cross-disciplinary study on use of glucose in detecting cancer.
- Irreversible tissue loss seen within 40 days of spinal cord injury
- From Bedside to Bench in the Institute’s MRC Centre for Neuromuscular Diseases
- Centralising acute stroke services has saved more than 400 lives since 2010
- Rapid Response Innovation Award from The Michael J. Fox Foundation
- Predicting Language Outcome and Recovery After Stroke (PLORAS) project launches new website
- BRC awards over £500k to neuroscience projects
- ABTA Winners
- Diabetes drug could help treat Parkinson's Disease
- Clinical trials are vital tools in stroke research
- New gene identified for Dominant Congenital Spinal Muscular Atrophy and Hereditary Spastic Paraparesis
- Teaching Awards 2013
- 14th Annual Queen Square Symposium
- TRACK-HD study identifies early predictors of disease progression in Huntington’s disease
- The Great Brain Experiment: crowdsourcing data on how we think and act
- Psychogenic diseases linked to abnormal brain activity
- Human Brain Project wins major EU funding
- Gene mutation causes familial form of cranio-cervical dystonia
- Professor Ray Dolan awarded prestigious Klaus Joachim Zülch Prize
- Professor Dimitri Kullmann elected Editor of Brain
- IoN News Archive (2012)
- IoN News Archive (2011)
- IoN News Archive (2010)
- IoN News Archive (2009)
- Professor Hardy awarded Thudichum Medal by Biochemical Society
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New £20m centre pioneers first-in-man trials for neurodegenerative diseases
15 November 2013
A specialist £20 million research centre, funded by the Wolfson Foundation and dedicated to carrying out first-in-human studies, opens in London today. Researchers at the Leonard Wolfson Experimental Neurology Centre (LWENC) will investigate exciting new therapies for neurodegenerative diseases such as Alzheimer’s and Parkinson’s.
The LWENC will receive its first patients in early 2014 and one of the first trials to be carried out at the facility will investigate whether immunotherapy can be used to tackle familial Alzheimer’s disease – a debilitating illness which can affect people in their 30s and 40s.
The new centre, located at the heart of the National Hospital for Neurology and Neurosurgery, has been funded by a £20 million award from the Wolfson Foundation to UCL. In addition to setting up the experimental neurology centre, the money has also been used to establish a new education and research programme that builds on UCL’s cross-disciplinary expertise in neuroscience to provide unique training opportunities for future generations of neurodegenerative disease researchers.
The grant is the largest single award ever made by the Foundation and one of the largest philanthropic donations in UCL’s history.
Paul Ramsbottom, Chief Executive of The Wolfson Foundation, says: “Our aim is to support excellence in science, medicine, health, education and the arts. With this award we wanted to highlight the fact that research into neurodegenerative diseases is relatively underfunded".
Nick Fox, Professor of Neurology at UCL and a Principal Investigator in the new Leonard Wolfson Experimental Neurology Centre, says: “At the Leonard Wolfson Experimental Neurology Centre we aim to speed up the development and validation of treatments, and open an earlier window to patients through which we can provide treatment and try to minimise the damage caused by neurodegenerative disease.”
Professor Alan Thompson, Dean of the UCL Faculty of Brain Sciences, says: “The Leonard Wolfson Centre will be the perfect bridge between the research strengths of UCL Neuroscience and the application of potential new therapies to patients with neurodegenerative disorders in the expert clinical setting of Queen Square. It will facilitate the all-important step of translating drug discovery into effective treatment.”
Professor John Duncan, divisional clinical director for the National Hospital for Neurology and Neurosurgery, says: "This centre will see the first treatments for debilitating neurodegenerative conditions, and will bring forward when these treatment can be offered in the clinics. This is a huge step forward and is only possible with the close cooperation of University, Hospital and the Wolfson Foundation."
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