Division of Infection and Immunity


Professor Tim McHugh

Director, Centre for Clinical Microbiology (CCM)
Professor of Medical Microbiology


Research in the Centre for Clinical Microbiology (CCM) focusses on the improved diagnosis and treatment of microbial infections with particular reference to the evolution of antimicrobial resistance.

Research summary

The work of CCM has an emphasis on respiratory infection with studies on the microbiome and resistome in patients with chronic lung disease such as COPD. A significant element of the CCMs work is to contribute to all stages of the TB drug development pathway with projects on evaluation of new compounds as well as supporting the laboratory aspects of phase II and III clinical trials. An underlying theme is the development of biomarkers of treatment outcome, whether transcriptomic analysis of in vitro treatments or the more complex picture of monitoring outcome in patients.

An important element of the work of CCM is capacity development, we provide training for laboratory scientists both on site and in London participating in several networks designed to enhance skills in microbiology laboratories. A recent collaboration is with colleagues in the Bartlett to develop the Biosafety Design Initiative, which undertakes training and research focussed on reducing transmission of infections in the built environment.


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