Dr Emma Morris

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Emma Morris

Dr Emma Morris

Reader in Immunology and Immunotherapy

Dr. Emma Morris

Contact

Dr Emma Morris
UCL Institute of Immunity and Transplantation
Department of Immunology
Royal Free Hospital
Rowland Hill Street
London NW3 2PF
UK
e.morris [at] ucl.ac.uk
emma.morris2 [at] nhs.net
T. +44 (0)20 7794 0500  Ext. 22475

Research area

Cell and Gene Therapy
T cell Immunology and Tumour Immunology
Allogeneic stem cell transplantation for Haematological Malignancies and Primary Immune Deficiencies

Research summary

My research group is interested in altering both the specificity and the function of gene-modified immune cells. These immune cells can then be used to treat cancer, infection or immune system disorders.

My research team investigates basic cellular and molecular mechanisms that influence how immune cells behave and how they recognise that cancer cells are different to normal cells, or why, in some cases, this does not occur. We are exploring ways to alter the genetic programming of these cells to improve their function and enhance their ability to kill cancer cells.

We also run a number of phase I (‘first in human’) clinical trials exploring the safety of these treatments in adult patients, where other treatments may have failed. These new approaches to cell therapy can be used in isolation or together with a stem cell (bone marrow) transplant procedure.

I trained in Clinical Medicine at the University of Cambridge before specialising in Haemato-oncology and allogeneic bone marrow transplantation. I am currently a Transplant Consultant at University College London Hospital NHS FT and the Royal Free London NHS FT. In receive research funding from the LLR, MRC, CRUK and the Wellcome Trust.

I am currently one of the NIHR UCLH/UCL Biomedical Research Centre Directors (Infection, Inflammation and Immunity Programme Director).

Patient involvement

I am Clinical Lead for the Primary Immune Deficiency Adult Stem Cell Transplant Programme at the Royal Free London NHS Trust, which is located within the Institute. Our clinical team cares for over 600 patients with PID, and we now have specific clinics to see patients referred for consideration of transplant.

We have many research studies taking place in the department, which we invite our patients to enrol for. These include projects to examine immune genes and immune cells that will give us more insight into the causes of PID and help us to design better diagnosis and treatment options.  

We also run clinical trials using gene and cell therapy approaches to treat immune disorders.

Group members

LLR Programme Grant:
Sharyn Thomas
Angelika Holler
Shao-An Xue
Graham Wright

PhD Students:
Bernardo Alvares
Anjum Khan (2nd Supervisor)
Alice Piapi
Chen Yuen

Clinical Trials:
Rachel Richardson
Rita Tendeiro Rego

Corneal Stem Cell Transplant Immunology Group collaboration:
Alex Shortt (Co-PI)
Piv Sagoo

Page last modified on 26 feb 15 16:26