| GS-US-380-1489: A Phase 3, Randomized, Double-Blind Study to Evaluate the Safety and Efficacy of GS-9883/Emtricitabine/Tenofovir Alafenamide Versus Abacavir/Dolutegravir/Lamivudine in HIV-1 Infected, Antiretroviral Treatment-Naïve Adults | Dr Laura Waters | Ongoing |
| GS-US-380-1490: A Phase 3, Randomized, Double-Blind Study to Evaluate the Safety and Efficacy of GS-9883/Emtricitabine/Tenofovir Alafenamide Versus Dolutegravir + Emtricitabine/Tenofovir Alafenamide in HIV-1 Infected, Antiretroviral Treatment-Naïve Adults | Dr Laura Waters | Ongoing |
| Royal Free HIV Cohort Study | Dr Colette Smith & Dr Fiona Lampe | Ongoing |
| Siyaphambili Youth | Dr Andrew Gibbs, Dr Jenevieve Mannell | Ongoing |
| EuroSIDA: A prospective observational cohort study of HIV-positive individuals in Europe, Israel and Argentina | Professor Amanda Mocroft | Ongoing |
| FLAIR: A Study to Evaluate the Efficacy, Safety, and Tolerability of Long-acting Intramuscular Cabotegravir and Rilpivirine for Maintenance of Virologic Suppression Following Switch From an Integrase Inhibitor in HIV-1 Infected Therapy Naive Participants | Prof Sarah Pett | Ongoing |
| Icona Network | Dr Alessandro Cozzi-Lepri | Ongoing |
| MAVMET: A multicentre, 48 week randomised controlled factorial trial of adding maraviroc and/or metformin for hepatic steatosis in HIV-1-infected adults on combination antiretroviral therapy | Prof Sarah Pett | Ongoing |
| Modelling and cost effectiveness analysis to inform response to high levels of HIV drug resistance in sub-Saharan Africa, including deployment of new drug regimens (HIV Synthesis Model) | Professor Andrew Phillips | Ongoing |
| NATSAL: The National Survey of Sexual Attitudes and Lifestyles | Prof Cath Mercer/ Prof Pam Sonnenberg | Ongoing |
| Needs Informed model of Care for people living with HIV (NICHE) | Professor Alison Rodger and Dr Fiona Lampe | Ongoing |
| POPPY Sleep Substudy: study looking at the effects of being HIV positive and being on antiretroviral medication may have on sleeping and sleep pattern | Prof Caroline Sabin (UCL lead) | Ongoing |
| Positive Voices: The national survey of people living with HIV | Prof Richard Gilson | Ongoing |
| POWER Project: Protecting women from economic shocks to fight HIV in Africa | Dr Aurelia Lepine | Ongoing |
| PrEP IMPACT Trial: A pragmatic health technology assessment of PrEP and implementation | Prof Richard Gilson | Ongoing |
| HIV BioResource | Prof Fiona Burns | Ongoing |
| The HIV Modelling Consortium | Professor Andrew Phillips | Ongoing |
| AMBER: A Phase 3, randomized, active-controlled, double-blind study to evaluate efficacy and safety of darunavir/cobicistat/emtricitabine/tenofovir alafenamide (D/C/F/TAF) once daily fixed dose combination regimen versus a regimen consisting of darunavir/cobicistat fixed dose combination coadministered with emtricitabine/tenofovir disoproxil fumarate fixed dose combination in antiretroviral treatment-naïve human immunodeficiency virus type 1 infected subjects. (TMC114FD2HTX3001) | Dr Laura Waters | Ongoing |
| Analysing humoral and cellular immune responses to vaccination during chronic infection | Dr Dimitra Peppa, Prof Richard Gilson, and Dr Laura Waters | Ongoing |
| Assessing the impact of introducing online postal self-sampling for sexually transmitted infections into sexual health provision within the UK on health inequalities, access to care and clinical outcomes (ASSIST) | Prof Fiona Burns & Dr Jo Gibbs | Ongoing |
| Attitudes to, and Understanding of Risk of Acquisition of HIV over time (AURAH2) | Prof Alison Rodger | Ongoing |
| BESTT Women's Study: Bone Evaluation in HIV-positive women who switch from Truvada/NNRTI to Triumeq | Dr Laura Waters | Ongoing |
| CASCADE study | Professor Kholoud Porter | Ongoing |
| TANGO: A Phase III, randomized, multicenter, parallel-group, non-inferiority study evaluating the efficacy, safety, and tolerability of switching to dolutegravir plus lamivudine in HIV-1-infected adults who are virologically suppressed | Prof Sarah Pett | Ongoing |
| TB:HIV - Tuberculosis among HIV-positive Patients: An International Prospective Observational Cohort Study | Professor Amanda Mocroft | Ongoing |
| The UK Collaborative HIV Cohort (UK CHIC) Study | Prof Caroline Sabin | Ongoing |
| GS-US-292-1823: A Phase 3b, Randomised, Open-Label Study to Evaluate the Safety and Efficacy of Switching from Regimens Consisting of ABC/3TC plus a Third Antiretroviral Agent to the E/C/F/TAF Fixed-Dose Combination (FDC) in Virologically-Suppressed HIV-1 Infected Adult Subjects | Dr Laura Waters | Completed |
| GS-US-292-1826: A Phase 3b, Randomised, Open-Label Study to Evaluate Switching from a TDF Containing Regimen to E/C/F/TAF Fixed-Dose Combination (FDC) in Virologically-Suppressed, HIV-1 Infected Subjects Aged ≥ 60 Years | Dr Laura Waters | Completed |
| HIV Allocative Efficiency and Financial Commitment Studies in Eastern Europe and Central Asia, using Optima | Prof Jolene Skordis | Completed |
| HIV Indicator Diseases across Europe Study (HIDES) | Professor Amanda Mocroft | Completed |
| The Co-morbidities in relation to HIV/AIDS (COBRA) study | Prof Caroline Sabin | Completed |
| Data Collection on Adverse events of Anti-HIV Drugs (D:A:D) | Prof Caroline Sabin (UCL)/Dr Lene Ryom (CHIP) | Completed |
| EuroCoord: Enhancing clinical & epidemiological HIV research in Europe through cohort collaboration | Prof Kholoud Porter | Completed |
| NIHR HPRU: Health Protection Research Unit in Blood Borne and Sexually Transmitted Infections | Prof Caroline Sabin | Completed |
| Optimising the Public Health Benefits of Sex Work Regulation in Senegal: A Formative Study | Dr Aurelia Lepine | Completed |
| Partners of people on ART - a New Evaluation of the Risks (The PARTNER study) | Prof Alison Rodger | Completed |
| Positive tRansItions through Menopause (PRIME) | Dr Shema Tariq | Completed |
| STAR HIV Self-Testing Africa | Dr Valentina Cambiano (UCL lead); Liz Corbett (LSHTM), Karin Hatzold (PSI) | Completed |
| SUPA: Supporting Uptake and adherence to antiretrovirals | Prof Caroline Sabin (IGH lead) | Completed |
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