UCL Great Ormond Street Institute of Child Health



Publications co-authored by the Confocal Facility Manager

  • Delalande JM, Natarajan D, Vernay B, Finlay M, Ruhrberg C, Thapar N, Burns AJ. Vascularisation is not necessary for gut colonisation by enteric neural crest cells. Dev Biol. 2014 Jan 15;385(2):220-9. PubMed PMID: 24262984.
  • Worth AJ, Metelo J, Bouma G, Moulding D, Fritzsche M, Vernay B, Charras G, Cory GO, Thrasher AJ, Burns SO. Disease-associated missense mutations in the EVH1 domain disrupt intrinsic WASp function causing dysregulated actin dynamics and impaired dendritic cell migration. Blood. 2013 Jan 3;121(1):72-84. PubMed PMID: 23160469.
  • Himoudi N, Morgenstern DA, Yan M, Vernay B, Saraiva L, Wu Y, Cohen CJ, Gustafsson K, Anderson J. Human γδ T lymphocytes are licensed for professional antigen presentation by interaction with opsonized target cells. J Immunol. 2012 Feb 15;188(4):1708-16. PubMed PMID: 22250090.
  • Lange S, Gögel S, Leung KY, Vernay B, Nicholas AP, Causey CP, Thompson PR, Greene ND, Ferretti P. Protein deiminases: new players in the developmentally regulated loss of neural regenerative ability. Dev Biol. 2011 Jul 15;355(2):205-14. PubMed PMID: 21539830.
  • Gaston-Massuet C, Andoniadou CL, Signore M, Jayakody SA, Charolidi N, Kyeyune R, Vernay B, Jacques TS, Taketo MM, Le Tissier P, Dattani MT, Martinez-Barbera JP. Increased Wingless (Wnt) signaling in pituitary progenitor/stem cells gives rise to pituitary tumors in mice and humans. Proc Natl Acad Sci U S A. 2011 Jul 12;108(28):11482-7. PubMed PMID: 21636786.
  • Ng KE, Joly P, Jayasinghe SN, Vernay B, Knight R, Barry SP, McComick J, Latchman D, Stephanou A. Bio-electrospraying primary cardiac cells: in vitro tissue creation and functional study. Biotechnol J. 2011 Jan;6(1):86-95. PubMed PMID: 21053334.

Selection of Confocal Facility Users' Publications


  • HIC2 is a novel dosage-dependent regulator of cardiac development located within the distal 22q11 deletion syndrome region. Dykes IM, Lammerts van Bueren K, Ashmore RJ, Floss T, Wurst W, Szumska D, Bhattacharya S, Scambler PJ. Circ Res. 2014 Apr 18. PubMed PMID: 24748541.


  • Preservation of micro-architecture and angiogenic potential in a pulmonary acellular matrix obtained using intermittent intra-tracheal flow of detergent enzymatic treatment. Maghsoudlou P, Georgiades F, Tyraskis A, Totonelli G, Loukogeorgakis SP, Orlando G, Shangaris P, Lange P, Delalande JM, Burns AJ, Cenedese A, Sebire NJ, Turmaine M, Guest BN, Alcorn JF, Atala A, Birchall MA, Elliott MJ, Eaton S, Pierro A, Gilbert TW, De Coppi P. Biomaterials. 2013 Sep;34(28):6638-48.PMID: 23727263.


  • Prasongchean W, Bagni M, Calzarossa C, De Coppi P, Ferretti P. Amniotic fluid stem cells increase embryo survival following injury. Stem Cells Dev. 2012 Mar 20;21(5):675-88.
  • Di WL, Semenova E, Larcher F, Del Rio M, Harper JI, Thrasher AJ, Qasim W. Human involucrin promoter mediates repression-resistant and compartment-specific LEKTI expression. Hum Gene Ther. 2012 Jan;23(1):83-90.
  • Freem LJ, Delalande JM, Campbell AM, Thapar N, Burns AJ. Lack of organ specific commitment of vagal neural crest cell derivatives as shown by back-transplantation of GFP chicken tissues. Int J Dev Biol. 2012;56(4):245-54.
  • Lakowski J, Han YT, Pearson RA, Gonzalez-Cordero A, West EL, Gualdoni S, Barber AC, Hubank M, Ali RR, Sowden JC. Effective transplantation of photoreceptor precursor cells selected via cell surface antigen expression. Stem Cells. 2011 Sep;29(9):1391-404. doi: 10.1002/stem.694. PubMed PMID: 21774040; PubMed Central PMCID: PMC3303132.
  • LKenny GD, Villegas-Llerena C, Tagalakis AD, Campbell F, Welser K, Botta M, Tabor AB, Hailes HC, Lythgoe MF, Hart SL. Multifunctional receptor-targeted nanocomplexes for magnetic resonance imaging and transfection of tumours. Biomaterials. 2012 Oct;33(29):7241-50.
  • Writer MJ, Kyrtatos PG, Bienemann AS, Pugh JA, Lowe AS, Villegas-Llerena C, Kenny GD, White EA, Gill SS, McLeod CW, Lythgoe MF, Hart SL. Lipid peptide nanocomplexes for gene delivery and magnetic resonance imaging in the brain. J Control Release. 2012 Sep 10;162(2):340-8.
  • Bennett K, Heywood W, Di WL, Harper J, Clayman GL, Jayakumar A, Callard R, Mills K. The identification of a new role for LEKTI in the skin: The use of protein 'bait' arrays to detect defective trafficking of dermcidin in the skin of patients with Netherton syndrome. J Proteomics. 2012 Jul 16;75(13):3925-37. Epub 2012 May 12.


  • Smart N, Bollini S, Dubé KN, Vieira JM, Zhou B, Davidson S, Yellon D, Riegler J, Price AN, Lythgoe MF, Pu WT, Riley PR. De novo cardiomyocytes from within the activated adult heart after injury. Nature. 2011 Jun 8;474(7353):640-4.
  • Bennett K, Heywood W, Di WL, Harper J, Clayman GL, Jayakumar A, Callard R, Mills K. The identification of a new role for LEKTI in the skin: The use of protein 'bait' arrays to detect defective trafficking of dermcidin in the skin of patients with Netherton syndrome. J Proteomics. 2012 Jul 16;75(13):3925-37. Epub 2012 May 12.
  • Bouma G, Mendoza-Naranjo A, Blundell MP, de Falco E, Parsley KL, Burns SO,Thrasher AJ. Cytoskeletal remodeling mediated by WASp in dendritic cells is necessary for normal immune synapse formation and T-cell priming. Blood. 2011 Sep 1;118(9):2492-501.
  • Mukherjee S, Santilli G, Blundell MP, Navarro S, Bueren JA, Thrasher AJ. Generation of functional neutrophils from a mouse model of X-linked chronic granulomatous disorder using induced pluripotent stem cells. PLoS One. 2011 Mar 3;6(3):e17565.
  • Di WL, Larcher F, Semenova E, Talbot GE, Harper JI, Del Rio M, Thrasher AJ, Qasim W. Ex-vivo gene therapy restores LEKTI activity and corrects the architecture of Netherton syndrome-derived skin grafts. Mol Ther. 2011 Feb;19(2):408-16.
  • Tagalakis AD, He L, Saraiva L, Gustafsson KT, Hart SL. Receptor-targeted liposome-peptide nanocomplexes for siRNA delivery. Biomaterials. 2011 Sep;32(26):6302-15. Epub 2011 May 31.


  • Lakowski J, Baron M, Bainbridge J, Barber AC, Pearson RA, Ali RR, Sowden JC. Cone and rod photoreceptor transplantation in models of the childhood retinopathy Leber congenital amaurosis using flow-sorted Crx-positive donor cells. Hum Mol Genet. 2010 Dec 1;19(23):4545-59. Epub 2010 Sep 21. PubMed PMID: 20858907; PubMed Central PMCID: PMC2972691.
  • Gualdoni S, Baron M, Lakowski J, Decembrini S, Smith AJ, Pearson RA, Ali RR, Sowden JC. Adult ciliary epithelial cells, previously identified as retinal stem cells with potential for retinal repair, fail to differentiate into new rod photoreceptors. Stem Cells. 2010 Jun;28(6):1048-59. PubMed PMID: 20506130.
  • Kane NM, Nowrouzi A, Mukherjee S, Blundell MP, Greig JA, Lee WK, Houslay MD, Milligan G, Mountford JC, von Kalle C, Schmidt M, Thrasher AJ, Baker AH. Lentivirus-mediated reprogramming of somatic cells in the absence of transgenic transcription factors. Mol Ther. 2010 Dec;18(12):2139-45.
  • Freem LJ, Escot S, Tannahill D, Druckenbrod NR, Thapar N, Burns AJ. The intrinsic innervation of the lung is derived from neural crest cells as shown by optical projection tomography in Wnt1-Cre;YFP reporter mice. J Anat. 2010 Dec;217(6):651-64