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Great Ormond Street Hospital and UCL Great Ormond Street Institute of Child Health appoint new Chair to drive forward new treatments for childhood brain tumours

8 March 2018

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Great Ormond Street Hospital Children’s Charity has established a new Chair in neuro-oncology, and are delighted that Darren Hargrave has been appointed to the post which will be working across UCL Great Ormond Street Institute of Child Health (ICH) and Great Ormond Street Hospital.

Improving outcomes for cancer is a priority in the United Kingdom and has received a major boost as a result of a strategic initiative between the Great Ormond Street Hospital for Children NHS Foundation Trust, UCLs Great Ormond Street Institute of Child Health, UCLs Cancer Institute and Great Ormond Street Hospital Children’s Charity. These organisations have come together with a commitment to make a strategic investment and build capacity in pediatric cancer research.

The charity created this Chair as part of a commitment to invest more than £50 million over five years in research into rare and complex childhood conditions, including very rare and hard-to-treat cancers. Brain tumours and those affecting the nervous system are the leading cause of cancer death in children, and survival rates lag behind other cancer types.

Peter Steer, Chief Executive of Great Ormond Street Hospital said: “Pediatric neuro-oncology is an area of unmet clinical need. The funding of this Chair will enable Darren Hargrave to expand and develop his research programme and drive forward new treatments for childhood brain tumours from discovery to cure.”

Professor Rosalind Smyth, Director of UCL Great Ormond Street Institute of Child Health said: “The outlook for children with brain tumours has not shown the same rapid improvements in prognosis which have been witnessed for other childhood cancers in recent decades. The world-leading research programme which Darren Hargrave will be able to develop as a result of this appointment has the potential to make a real difference to our ability to treat these tumours more effectively.”

Kiki Syrad, Director of Grants and Impact at Great Ormond Street Hospital Children’s Charity said: “Since arriving at GOSH Darren Hargrave has built up an impressive world-leading research programme, and we’re delighted that thanks to our generous supporters we are now able to continue to help him expand his research, which we hope will benefit children at GOSH and beyond.”  

Darren Hargrave said “It is a great honour for me to be appointed to this role. I have dedicated my career to developing better and kinder treatments for children with brain tumours. I passionately believe that by increasing our knowledge of the biology of brain tumours we can translate this into the clinic to improve the length, and also quality of survival for these children. My new post will allow me to develop more translational brain tumour research activity with colleagues at the ICH, nationally and internationally."

Darren Hargrave joined GOSH in 2011 as Consultant paediatric oncologist having previously worked at the Royal Marsden Hospital in London. He specialises in paediatric neuro-oncology and the development of new anti-cancer drugs for children and adolescents. He trained in the UK and Canada and is a member of both national and international groups in the fields of paediatric neuro-oncology and drug development. He will be the next Chair of the European SIOPE Paediatric Brain Tumour Group and is a Chief Investigator of several completed, on-going and planned clinical trials in paediatric cancer.


For media enquiries, please contact:

Ruth Maurice Tel: 0207 239 3125 Email: ruth.maurice@GOSH.org

Notes to Editor

About Great Ormond Street Hospital for Children NHS Foundation Trust

Great Ormond Street Hospital is one of the world’s leading children’s hospitals with the broadest range of dedicated, children’s healthcare specialists under one roof in the UK. The hospital’s pioneering research and treatment gives hope to children from across the UK with the rarest, most complex and often life-threatening conditions. Our patients and families are central to everything we do – from the moment they come through the door and for as long as they need us.

About Great Ormond Street Hospital Children’s Charity

Great Ormond Street Hospital Children’s Charity needs to raise money to support the hospital to give children who need help the most, the best chance for life. The charity funds research into pioneering new treatments for children, provides the most up to date medical equipment, funds support services for children and their families and supports the essential rebuilding and refurbishment of the hospital. You can help us to provide world class care for our patients and families. For more information visit www.gosh.org

About the UCL Great Ormond Street Institute of Child Health (ICH)
The UCL Great Ormond Street Institute of Child Health is part of the Faculty of Population Health Sciences within the School of Life and Medical Sciences at UCL. Together with its clinical partner Great Ormond Street Hospital for Children (GOSH), it forms the largest concentration of children's health research in Europe.
For more information visit www.ucl.ac.uk/ich