NIHR Health Protection Research Unit in Evaluation of Interventions


HPRU Co-Directors
Professor Matt Hickmann and Dr Isabel Oliver, University of Bristol
UCL team members
Professor Susan Michie, Dr Annegret Schneider
Start and end dates
2014 - 2019
Funder National Institute for Health Research (NIHR)


Project details

The NIHR Health Protection Research Unit (HPRU) in Evaluation of Interventions uses a multi-disciplinary research team to undertake applied research on the development and evaluation of interventions, focusing on infection. It is a partnership between University of Bristol and Public Health England (PHE) in collaboration with UCL, Cambridge Medical Research Council (MRC) Biostatistics Unit and University of the West of England.

The Behavioural Science workstream of the HPRU applies empirical evidence and theory to identify key behaviours, barriers and facilitators, intervention components, and hypothesised mechanisms of action for proposed interventions. The current research priorities for the Behavioural Science workstream are to design and evaluate interventions to reduce:

  • Inappropriate antibiotics prescribing in primary care settings;
  • Unnecessary visits by carers/parent to GPs with children with respiratory tract infections; and
  • Visits to primary care settings for self-limiting conditions.

The Behavioural Science workstream of the HPRU also provides advice for reactive evaluation projects. Two current reactive projects are:

  • A mixed method evaluation of the UK Ebola screening programme and returning health care worker scheme; and
  • A rapid evaluation of the acute trust toolkit for the early detection, management and control of Carbapenemase-producing Enterobacteriaceae.