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Digital persuasive game innovation to improve patient management of UTIs in the NHS and Africa

Transformative Technology funding awarded in 2023-24

variety of different pills

28 October 2024

Grant


Grant: Special Initiative - Research Innovation Award
Year awarded: 2023-24
Amount awarded: £19,872

Academics 


  • Prof Patty Kostkova, Institute of Risk and Disaster Reduction, Mathematical & Physical Sciences
  • Dr Ai-Nee Lim, Whittington Health NHS Trust

Urinary Track infections (UTI) are one of the most prevalent bacterial infections treated in the NHS affecting mostly women. Traditionally, UTI are treated using antibiotics prescribed by GPs and nurses in primary care, however, recently, to alleviate the pressure on the NHS prescribers, registered healthcare professionals are authorized to prescribe and manage UTI in the community. Subsequently, evidence shows that following the guidelines by non-prescribers is a major concern.

Mobile serious persuasive games are a cutting-edge digital decision support intervention that demonstrated the potential to change antibiotics prescription behaviour and educate healthcare professionals at the point of care. They could provide much needed reassurance in complex UTI management decisions, and successfully address guideline adherence gap in the NHS.

The award-winning Centre for Digital Public Health in Emergencies, with years of digital innovation expertise, leads this multi-disciplinary cross-boundary international team including a consultant pharmacist and antibiotic stewardship (AMS) lead in the NHS, and a clinical microbiologist in Nigeria who will ensure the prototype designed for the NHS could be easily adapted and localised for UTI management. This seed project has the potential to make a truly global long-term impact while also contributing to the fight against antimicrobial resistance.

Digital persuasive serious games technology has demonstrated high effectiveness in enabling behaviour change and holds great potential in educating healthcare professionals on UTI management and addressing guideline adherence gaps (Luedtke 2023). UTI transformative technology will also support training, supervision of non-prescribers through a dashboard, deliver audit of quality of care, demonstrate AMR prescription decision behaviour change, increase compliance and provide seamlessly app-collected data for robust evaluation of effectiveness.

This project consortium builds of a fruitful interdisciplinary collaboration between UCL dPHE Centre and the Whittington Health NHS Trust having identified a unique synergic opportunity for digital intervention to transform pressing challenges around prescribing and management of UTI by non-prescribers that could improve the quality of care for thousands of patients in North Centre London through Dr Lim’s leadership on AMS in this area. A specification and a mock-up serious game app was successfully presented to consultants and pharmacists in Whittington Health NHS Trust in autumn 2023 and enthusiastically received.

Through this funding, this research aims to roll out a large sustainable digital innovation initiative, leveraging the perfect consortium at UCL, NHS and Africa, enhanced by the new social enterprise, dramatically transforming the management of UTI and AMR UTI prescribing for thousands of patients in high and LMIC settings on two continents over the next decade.

This project addresses this hidden gender aspect of this common debilitating condition improving quality of care and preventing recurrence of UTI for thousands of female patients in the NHS and in Africa. While the NHS has been subject to drastic cuts, this project when scaled up will improve the quality of patient care delivered in the community by non-prescribers saving valuable consultants time for more complex cases and conditions. This will address inequality, gaps in care, and challenges in guidelines compliance witnessed at the moment. In Africa, the project will bring the importance of UTI management to the forefront of community care and dramatically improve the training and prescription compliance in line with local UTI guidelines appropriate for resource constrained settings. Finally, this project addresses one of the most pressing global societal challenges faced by humanity today – antimicrobial resistance (AMR) expected to amount to 10 million deaths and cost the global economy £66 trillion by 2025, according to WHO.

 

Outputs and Impacts

  • The project developed the first prototype of the GADSA (Gamified Antimicrobial Stewardship Decision Support App) UTI decision support app and successfully presented it to the key stakeholders in NHS Whittington and UCH. This is in line with the new government strategy for a Digital NHS and focus on prevention rather than cure.
  • The project team have advanced their collaboration with Infection Control African Network (ICAN) involving over 30 African countries and plan to scale up the technology in Africa in the next stage.
  • Prof Patty Kostkova is setting up a Social Venture supported by UCLB to sustainably support the maintenance of the UTI apps on a long term basis.
  • The project strengthened interdisciplinary cross-sectoral collaboration and enabled a technology transfer opportunity between UCL and the NHS.For example, a fruitful interdisciplinary collaboration was gained between UCL Centre for Digital Public Health in Emergencies and the Whittington Health NHS Trust through a unique synergic opportunity for digital intervention to transform pressing challenges around prescribing and management of UTI by non-prescribers, that could improve the quality of care for thousands of patients in North Centre London through Dr Lim’s leadership on AMS in this area.
  • Large research funding grants were submitted and further funding is being sought for a full development and pilot testing in the NHS. Research bids have been submitted for: NIHR Programme Development Grants (PDG), pilot NIHR Programme Grants for Applied Research (PGfAR), scale up deployment with several NHS Trusts Wellcome Trust and international scale up to Africa.

Looking forward

  • The project team are working on further funding applications to secure resources for a full pilot deployment in the Whittington Trust. In the next stage, the plan is to scale up the apps across more NHS Trusts, including UCH who expressed interest, and develop a dashboard for the supervisors for audit and reporting. The aim is to get it approved by the Medicines and Healthcare products Regulatory Agency (MHRA) and roll out across the NHS.
  • Long term impacts will include successful management of UTI across the NHS and in the community, reaching out to thousands of patients.

A phone showing the UTI app developed
a smartphone open on the UTI app

Photo: GADSA UTI app demo