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Institute for Global Health

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Diarmuid Nugent

Diarmuid's thesis title is "Human papillomavirus (HPV) infection in men who have sex with men (MSM): optimisation of prevalence monitoring and treatment."

His primary supervisor is Dr Richard Gilson.

To get in touch with Diarmuid, please email him at d.nugent@ucl.ac.uk.

About Diarmuid

Diarmuid is a Speciality Registrar in Sexual Health and HIV Medicine based at the Mortimer Market Centre in London.  As an NIHR funded clinical academic trainee he has worked on many clinical trials of HIV treatment and prevention alongside being a clinician in genitourinary medicine. He is interested in sexual healthcare issues affecting men who have sex with men (MSM) including human papillomavirus (HPV), pre-exposure prophylaxis (PrEP) for HIV and viral hepatitis. He is co-author of the forthcoming updated European Guideline for the Management of Anogenital Warts (in press).

Thesis summary

Human papillomavirus (HPV) is a common, sexually transmitted viral infection which can cause warts and cancer.  Men who have sex with men are at high risk of both HPV infection and HPV-related disease, particularly anal cancer.  Vaccination against HPV has been available to MSM at selected sexual health clinics in the UK since 2016.  My MD thesis explores the indicators that may be used to monitor the impact of this vaccination programme.  I will evaluate through a cross sectional observational study whether residual specimens from sexual health screens can be used for this purpose.  I will also carry out a sub-analysis of a large clinical trial (HIPvac) which compares topical treatments and HPV vaccine/placebo for the treatment of anogenital warts to evaluate the study outcomes in MSM.