Screening and early detection to prevent anal cancer; development of a biomarker screening tool.
SEPAC is an observational anal pre-cancer screening study.
The study aims to develop and evaluate a primary screening tool for anal pre-cancer that would allow the identification and treatment of early disease, to reduce the morbidity and mortality associated with anal cancer.
We will recruit 1000 HIV-positive MSM aged 40 years or older from five participating HIV clinics across England. All participants will undergo high resolution anoscopy examination and have samples taken for biomarker analyses.
Links to other research
Other research from the UCL Centre for Clinical Research in Infection and Sexual Health
Other research from IGH in the UK