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Screening and early detection to prevent anal cancer; development of a biomarker screening tool.
Project Summary
SEPAC is an observational anal pre-cancer screening study.
The study aims to develop and evaluate a primary screening tool for anal pre-cancer that would allow the identification and treatment of early disease, to reduce the morbidity and mortality associated with anal cancer.
We will recruit 1000 HIV-positive MSM aged 40 years or older from five participating HIV clinics across England. All participants will undergo high resolution anoscopy examination and have samples taken for biomarker analyses.