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Can Large MPAs Protect Tuna and Sharks?

Thu, 04 Jun 2015 14:04:29 +0000

a guest blog by David Curnick, written for the 2015 Write About Research Competition. With a global human population of over 7 billion it is becoming ever more important to manage our natural resources effectively. For centuries, the oceans have been seen as an endless bounty, ripe for harvesting. However, this simply isn’t the case […]

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Prof Jürg Bähler publishes lead article on Fission Yeast in Cell journal

1 November 2012

Quantitative Analysis of Fission Yeast Transcriptomes and Proteomes in Proliferating and Quiescent Cells

Samuel Marguerat, Alexander Schmidt, Sandra Codlin, Wei Chen, Ruedi Aebersold, and Jürg Bähler

This article reports cellular numbers for all RNAs and most proteins in proliferating and non-dividing cells of fission yeast. Most mRNAs are expressed at only 1-10 copies/cell, while corresponding proteins show greater abundance and range, from less than 100 to over 1 million copies/cell. Only a minority of long non-coding RNAs are expressed at >1 copy/cell. In the smaller non-dividing cells, the protein content changes substantially and RNA concentrations greatly decrease. These RNA and protein concentrations inform about cell regulation and function.

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