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Gee Research Blog

Write About Research – A GEE Research Blog Competition

Tue, 03 Mar 2015 15:28:43 +0000

The GEE Research blog communicates UCL science with a wider, non-specialist audience, by providing short summaries of recent research in the department of UCL Genetics, Evolution and Environment. This provides an opportunity to engage with a broad audience, including other academics, students, members of the public, and even businesses and policy-makers. It is a great […]

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Was Fermentation Key to Yeast Diversification?

Tue, 17 Feb 2015 15:30:43 +0000

From bread to beer, yeast has shaped our diets and our recreation for centuries. Recent research in GEE shows how humans have shaped the evolution of this important microorganism. As well as revealing the evolutionary origins of modern fission yeast, the new study published in Nature Genetics this month shows how techniques developed for detecting […]

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Planning for the Future – Resilience to Extreme Weather

Thu, 15 Jan 2015 15:13:14 +0000

As climate change progresses, extreme weather events are set to increase in frequency, costing billions and causing immeasurable harm to lives and livelihoods. GEE’s Professor Georgina Mace contributed to the recent Royal Society report on “Resilience to Extreme Weather”, which predicts the future impacts of increasing extreme weather events, and evaluates potential strategies for improving […]

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Forecasting Extinction

Mon, 05 Jan 2015 11:33:21 +0000

Classifying a species as either extinct or extant is important if we are to quantify and monitor current rates of biodiversity loss, but it is rare that a biologist is handy to actually observe an extinction event. Finding the last member of a species is difficult, if not impossible, so extinction classifications are usually estimates […]

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Changing Perspectives in Conservation

Thu, 18 Dec 2014 12:15:44 +0000

Our views of the importance of nature and our place within have changed dramatically over the the last century, and the prevailing paradigm has profound influences on conservation from the science that is conducted to the policies that are enacted. In a recent perspectives piece for Science, GEE’s Professor Georgina Mace considered the impacts that […]

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Prof Jürg Bähler publishes lead article on Fission Yeast in Cell journal

1 November 2012

Quantitative Analysis of Fission Yeast Transcriptomes and Proteomes in Proliferating and Quiescent Cells

Samuel Marguerat, Alexander Schmidt, Sandra Codlin, Wei Chen, Ruedi Aebersold, and Jürg Bähler

This article reports cellular numbers for all RNAs and most proteins in proliferating and non-dividing cells of fission yeast. Most mRNAs are expressed at only 1-10 copies/cell, while corresponding proteins show greater abundance and range, from less than 100 to over 1 million copies/cell. Only a minority of long non-coding RNAs are expressed at >1 copy/cell. In the smaller non-dividing cells, the protein content changes substantially and RNA concentrations greatly decrease. These RNA and protein concentrations inform about cell regulation and function.

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