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Farr Institute London Short Courses

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Genetic Association Studies and Mendelian Randomisation

Mendelian randomisation studies have become increasingly popular in the past decade following the growth in availability of genome-wide data.

Initially this two-day course will cover basic concepts behind genetic association studies with focus on Genome-Wide Association Studies (GWAS).

The practical component will take participants through quality controlling genetic datasets as well as using the latest statistical methods and software to analyse and visualise results for genome-wide data.

The second part of the course will then focus on Mendelian Randomisation (MR), and more specifically using genetic variants identified through GWAS to estimate the causal relationship of a non-genetic risk factor on an outcome of interest.

The practicals will be implemented in PLINK, HAPLOVIEW, R and Stata.

Course Team

Dr Ghazaleh Fatemifar (Lead Tutor)
Dr Michail Katsoulis (Lead Tutor)
Dr Tom Palmer (Lead Tutor)
Dr Caroline Dale
Mr Okezie Uche-Ikonne