UCL Events


Lunch Hour Lecture: Why do people with Down syndrome develop dementia and what can we do about it?

1:00 pm to 2:00 pm, 26 March 2019

Lunch Hour Lectures

Event Information

Open to

All | UCL staff | UCL students | UCL alumni | Invitation Only




Emma Hart


Darwin Lecture Theatre
044: Darwin Building
Gower Street
United Kingdom

About the lecture: In the lecture, Dr. Wiseman will explain what we know about the development of dementia in people who have Down syndrome and what still needs to be understood. She will discuss the genetic cause of Down syndrome, and how this predisposes someone to develop early onset dementia. In particular, how researchers use cell and animal models and clinical data to workout which genes cause the early onset of dementia in people who have Down syndrome, and how this knowledge is being used to develop dementia treatments.

Link to Live Stream

About the Speaker

Dr. Wiseman

Dr. Wiseman, completed her PhD at the University of Edinburgh in 20017. Since then she has worked at UCL researching the early onset of Alzheimer’s disease-dementia in people who have Down syndrome (AD-DS). Down syndrome is a genetic condition, caused by having three copies of chromosome 21 rather than the two copies found in the general population. Dr. Wiseman’s research focuses how the extra copy of the genes cause the early onset of AD-DS. Her group uses a range of model systems to do this and they work closely with a number of other research groups (LonDownS Consortium) who undertake genetic and clinical AD-DS research. Dr. Wiseman also holds an Alzheimer’s Research Trust UK Senior Fellowship.