on cross-disciplinary global disability research.
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Members of the department contribute to IGH public meetings which bring
together expertise on global health issues from all faculties within
Contact: Sarah Ball, Tel: (internal x82 72 2352)
2012 Seminar Series
Title: 'Risk factors for CVD: 3 decades of findings from the British Regional Heart Study'
Speaker: S Goya Wannamethee, Professor in Epidemiology, Co-director of the British Regional Heart Study. Dept Primary Care and Population Health, UCL
The British Regional Heart Study (BRHS) is a large prospective study of cardiovascular disease (CVD) involving 7735 men aged 40-59 years drawn from general practices in 24 towns in the UK. The men were initially screened and examined in 1978-1980. The men were re-examined in detailed 20 years later in 1998-2000 when aged 60-79 and are currently undergoing a third re-examination 30 years after the initial screening (2010-2012). The men have been followed up since screening for cardiovascular morbidity, diabetes and all-cause mortality for over 30 years. The talk will focus on key findings (past and present) from the BRHS on on-going challenges and debates on risk factors in CVD over the last 30 years. This ranges from U-shaped curves in CVD epidemiology to the conjoined epidemic of obesity and the metabolic syndrome to the use of novel biomarkers in identifying people at high risk of developing CVD. We will focus in particular on the clinical use of the novel biomarkers C-reactive protein (CRP) and NT-proBNP in identifying those at high risk of CVD. I will also provide a brief overview of the future research of the BRHS.
Goya Wannamethee is Professor of Epidemiology in the Department of Primary Care and Population Health at UCL. She is co-director of the British Regional Heart Study (BRHS) a large UK prospective study of cardiovascular disease. Her research focuses on the causes, prediction and prevention of cardiovascular disease (CVD) and diabetes. Her primary interest has been on modifiable lifestyle factors including the associations between alcohol, physical activity, obesity, smoking and CVD and diabetes and on pathways linking these factors to outcome.
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