Research output

Research activities - in progress

BRHS Publications

2024: Ganbavale SG, Papachristou E, Mathers JC, Papacosta AO, Whincup PH, Wannamethee SG, Ramsay SE. Neighborhood Deprivation and Changes in Oral Health in Older Age: A Longitudinal Population-Based Study. Journal of Dental Research OnlineFirst Feb 2024 https://doi.org/10.1177/00220345231224337

2023

Ahmed A, Ambler G, Pinto Pereira SM, Lennon L, Papacosta O, Whincup P, et al. Stroke risk in older British men: Comparing performance of stroke-specific and composite-CVD risk prediction tools. Prev Med Rep. 2023;31:102098.

Bush KJ, Papacosta AO, Lennon LT, Rankin J, Whincup PH, Wannamethee SG, et al. Influence of neighborhood-level socioeconomic deprivation and individual socioeconomic position on risk of developing type 2 diabetes in older men: a longitudinal analysis in the British Regional Heart Study cohort. BMJ Open Diabetes Res Care. 2023;11(5).

Chen A, Lennon L, Papacosta O, Wannamethee SG. Association of night-time sleep duration and daytime napping with all-cause and cause-specific mortality in older British men: from the British Regional Heart Study. Sleep Medicine. 2023;109:32-9.

Global Cardiovascular Risk C, Magnussen C, Ojeda FM, Leong DP, Alegre-Diaz J, Amouyel P, et al. Global Effect of Modifiable Risk Factors on Cardiovascular Disease and Mortality. N Engl J Med. 2023;389(14):1273-85.

Kaptoge S, Sun L, Walker M, Spackman S, Pennells L, Seshasai SRK, et al. Life expectancy associated with different ages at diagnosis of type 2 diabetes in high-income countries: 23 million person-years of observation. Lancet Diabetes Endo. 2023;11(10):731-42.

Kimble R, McLellan G, Lennon LT, Papacosta AO, Mathers JC, Wannamethee SG, et al. Cohort Profile Update: The British Regional Heart Study 1978-2018: 40 years of follow-up of older British men. Int J Epidemiol. 2023;52(3):e187-e94.

Kimble R, Papacosta AO, Lennon LT, Whincup PH, Weyant RJ, Mathers JC, et al. The Relationships of Dentition, Use of Dental Prothesis and Oral Health Problems with Frailty, Disability and Diet Quality: Results from Population-Based Studies of Older Adults from the UK and USA. J Nutr Health Aging. 2023;27(8):663-72.

Kimble R, Papacosta AO, Lennon LT, Whincup PH, Weyant RJ, Mathers JC, et al. The Relationship of Oral Health with Progression of Physical Frailty among Older Adults: A Longitudinal Study Composed of Two Cohorts of Older Adults from the United Kingdom and United States. J Am Med Dir Assoc. 2023;24(4):468-74 e3.

Mitchell JJ, Hamer M, Blodgett JM, Wannamethee GS, Jefferis BJ. Associations between sporting physical activity and cognition in mid and later-life: Evidence from two cohorts. Scand J Med Sci Sports. 2023;33(8):1570-5.

Paluch AE, Bajpai S, Ballin M, Bassett DR, Buford TW, Carnethon MR, Chernofsky A... Steps for Health Collaborative. Prospective Association of Daily Steps With Cardiovascular Disease: A Harmonized Meta-Analysis.. Circulation, 2023;147 (2):122-131

Schmidt AF, Joshi R, Gordillo-Maranon M, Drenos F, Charoen P, Giambartolomei C, et al. Biomedical consequences of elevated cholesterol-containing lipoproteins and apolipoproteins on cardiovascular and non-cardiovascular outcomes. Commun Med-London. 2023;3(1).

Wang Q, Schmidt AF, Lennon LT, Papacosta O, Whincup PH, Wannamethee SG. Prospective associations between diet quality, dietary components, and risk of cardiometabolic multimorbidity in older British men. Eur J Nutr. 2023;62(7):2793-804.

Wannamethee SG, Atkins JL. Sarcopenic Obesity and Cardiometabolic Health and Mortality in Older Adults: a Growing Health Concern in an Ageing Population. Curr Diab Rep. 2023.

Zhou B, Sheffer KE, Bennett JE, Gregg EW, Danaei G, Singleton RK, et al. Global variation in diabetes diagnosis and prevalence based on fasting glucose and hemoglobin A1c. Nat Med. 2023.

2022

Coyte A, Perry R, Papacosta AO, Lennon L, Whincup PH, Wannamethee SG, et al. Social relationships and the risk of incident heart failure: results from a prospective population-based study of older men. Eur Heart J Open. 2022;2(1):oeab045.

Gaziano L, Sun L, Arnold M, Bell S, Cho K, Kaptoge SK et al. Emerging Risk Factors Collaboration/EPIC-CVD/Million Veteran Program. Mild-to-Moderate Kidney Dysfunction and Cardiovascular Disease: Observational and Mendelian Randomization Analyses. Circulation. 2022 Nov 15;146(20):1507-1517. doi: 10.1161/CIRCULATIONAHA.122.060700. Epub 2022 Oct 31. PMID: 36314129; PMCID: PMC9662821.

Kimble R, McLellan G, Lennon LT, Papacosta AO, Mathers JC, Wannamethee SG, Whincup PH, Ramsay SE. Cohort Profile Update: The British Regional Heart Study 1978-2018: 40 years of follow-up of older British men. Int J Epidemiol. 2022 Jun 3:dyac122. doi: 10.1093/ije/dyac122. Epub ahead of print. PMID: 35656703.

Kimble R, Papacosta AO, Lennon LT, Whincup PH, Weyant RJ, Mathers JC, Wannamethee SG, Ramsay SE. The Relationship of Oral Health With Progression of Physical Frailty Among Older Adults: A Longitudinal Study Composed of Two Cohorts of Older Adults From the United Kingdom and United States. J Am Med Dir Assoc. 2022 Dec 27:S1525-8610(22)00919-7. doi: 10.1016/j.jamda.2022.11.022. Epub ahead of print. PMID: 36584971.

Kotronia E, Brown H, Papacosta O, Lennon LT, Weyant RJ, Whincup PH, et al. Oral health problems and risk of incident disability in two studies of older adults in the United Kingdom and the United States. Journal of the American Geriatrics Society. 2022.

McKechnie DGJ, Patel M, Papacosta AO, Lennon LT, Ellins EA, Halcox JPJ, et al. Associations between inflammation, coagulation, cardiac strain and injury, and subclinical vascular disease with frailty in older men: a cross-sectional study. BMC Geriatr. 2022;22(1):405.

Paluch AE, Bajpai S, Bassett DR, Carnethon MR, Ekelund U, Evenson KR, et al. Daily steps and all-cause mortality: a meta-analysis of 15 international cohorts. Lancet Public Health. 2022;7(3):e219-e28.

Schutte R, Smith L, Wannamethee G. Alcohol-The myth of cardiovascular protection. Clinical Nutrition. 2022;41(2):348-55.

Tarp J, Fagerland MW, Dalene KE, Johannessen JS, Hansen BH, Jefferis BJ, et al. Device-measured physical activity, adiposity and mortality: a harmonised meta-analysis of eight prospective cohort studies. Br J Sports Med. 2022;56(13):725-32.

Wannamethee SG. Frailty and increased risk of cardiovascular disease: are we at a crossroad to include frailty in cardiovascular risk assessment in older adults? Eur Heart J. 2022;43(8):827-9.

Wannamethee SG, Papacosta O, Lennon L, Whincup PH, Rumley A, Lowe GDO. Haematological variables and risk of future venous thromboembolism in the British Regional Heart Study on men. Combined D-dimer and APTT as a predictive test for thromboembolism? Br J Haematol. 2022;198(3):587-94.

2021

Ahluwalia TS, Prins BP, Abdollahi M, et al. Genome-wide association study of circulating interleukin 6 levels identifies novel loci. Hum Mol Genet 2021; 30(5): 393-409. doi: 10.1093/hmg/ddab023. https://www.ncbi.nlm.nih.gov/pubmed/33517400

Gilani A, De Caterina R, Papacosta O, Lennon LT, Whincup PH, Wannamethee SG. Excessive Orthostatic Changes in Blood Pressure Are Associated With Incident Heart Failure in Older Men: A Prospective Analysis From the BRHS. Hypertension 2021; 77(5): 1481-9. doi: 10.1161/HYPERTENSIONAHA.120.15817. Epub 2021 Mar 15.

Gilani A, Ramsay SE, Welsh P, et al. Vitamin D deficiency is associated with orthostatic hypotension in older men: a cross-sectional analysis from the British Regional Heart Study. Age Ageing 2021; 50(1): 198-204. doi: 10.1093/ageing/afaa146.

Gordillo-Maranon M, Zwierzyna M, Charoen P, et al. Validation of lipid-related therapeutic targets for coronary heart disease prevention using human genetics. Nat Commun 2021; 12(1): 6120. doi: 10.1038/s41467-021-25731-z.

Joshi R, Wannamethee G, Engmann J, et al. Establishing reference intervals for triglyceride-containing lipoprotein subfraction metabolites measured using nuclear magnetic resonance spectroscopy in a UK population. Ann Clin Biochem 2021; 58(1): 47-53. doi: 10.1177/0004563220961753. Epub 2020 Oct 21.

Kotronia E, Brown H, Papacosta AO, et al. Oral health and all-cause, cardiovascular disease, and respiratory mortality in older people in the UK and USA. Sci Rep 2021; 11(1): 16452. doi: 10.1038/s41598-021-95865-z.

Kotronia E, Brown H, Papacosta AO, et al. Poor oral health and the association with diet quality and intake in older people in two studies in the UK and USA. Br J Nutr 2021; 126(1): 118-30. doi: 10.1017/S0007114521000180. Epub 2021 Jan 20. (Kotronia E, Brown H, Olia Papacosta A, et al. Poor oral health and the association with diet quality and intake in older people in two studies in the UK and USA - CORRIGENDUM. Br J Nutr 2021; 126(1): 160. doi: 10.1017/S0007114521000878. Epub 2021 Mar 22.)

Kotronia E, Wannamethee SG, Papacosta AO, et al. Poor Oral Health and Inflammatory, Hemostatic, and Cardiac Biomarkers in Older Age: Results From Two Studies in the UK and USA. J Gerontol A Biol Sci Med Sci 2021; 76(2): 346-51. doi: 10.1093/gerona/glaa096

McKechnie DG, Papacosta AO, Lennon LT, Ramsay SE, Whincup PH, Wannamethee SG. Frailty and incident heart failure in older men: the British Regional Heart Study. Open Heart 2021; 8(1). doi: 10.1136/openhrt-2021-001571

McKechnie DG, Papacosta AO, Lennon LT, Welsh P, Whincup PH, Wannamethee SG. Inflammatory markers and incident heart failure in older men: the role of NT-proBNP. Biomark Med 2021; 15(6): 413-25. doi: 10.2217/bmm-2020-0669. Epub 2021 Mar 12.

McKechnie DGJ, Papacosta AO, Lennon LT, et al. Subclinical cardiovascular disease and risk of incident frailty: The British Regional Heart Study. Exp Gerontol 2021; 154: 111522. doi: 10.1016/j.exger.2021.111522. Epub 2021 Aug 21.

McKechnie DGJ, Papacosta AO, Lennon LT, Ramsay SE, Whincup PH, Wannamethee SG. Associations between inflammation, cardiovascular biomarkers and incident frailty: the British Regional Heart Study. Age Ageing 2021; 50(6): 1979-87. doi: 10.1093/ageing/afab143

Schmidt AF, Hunt NB, Gordillo-Maranon M, et al. Cholesteryl ester transfer protein (CETP) as a drug target for cardiovascular disease. Nat Commun 2021; 12(1): 5640. doi: 10.1038/s41467-021-25703-3

Wannamethee SG, Papacosta O, Lennon L, Hingorani A, Whincup P. Adult height and incidence of atrial fibrillation and heart failure in older men: The British Regional Heart Study. Int J Cardiol Heart Vasc 2021; 35: 100835. doi: 10.1016/j.ijcha.2021.100835. eCollection 2021 Aug.

2020

Aggio D, Papachristou E, Papacosta O, Lennon LT, Ash S, Whincup P, Wannamethee SG, Jefferis BJ.Trajectories of physical activity from midlife to old age and associations with subsequent cardiovascular disease and all-cause mortality. J Epidemiol Community Health. 2020 Feb;74(2):130-136. doi: 10.1136/jech-2019-212706. Epub 2019 Nov 8. PMID: 31704805

Ahmed A, Pinto Pereira SM, Lennon L, Papacosta O, Whincup P, Wannamethee G. Cardiovascular Health and Stroke in Older British Men: Prospective Findings From the British Regional Heart Study. Stroke. 2020;51(11):3286-94. DOI: 10.1161/STROKEAHA.120.030546

Borges MC, Schmidt AF, Jefferis B, Wannamethee SG, Lawlor DA, Kivimaki M, et al. Circulating Fatty Acids and Risk of Coronary Heart Disease and Stroke: Individual Participant Data Meta-Analysis in Up to 16 126 Participants. J Am Heart Assoc. 2020;9(5):e013131.PMCID: PMC7335585 DOI: 10.1161/JAHA.119.013131

Brunner FJ, Waldeyer C, Ojeda F, Salomaa V, Kee F, Sans S, Thorand B, Giampaoli S, Brambilla P, Tunstall-Pedoe H, Moitry M, Iacoviello L, Veronesi G, Grassi G, Mathiesen EB, Söderberg S, Linneberg A, Brenner H, Amouyel P, Ferrières J, Tamosiunas A, Nikitin YP, Drygas W, Melander O, Jöckel KH, Leistner DM, Shaw JE, Panagiotakos DB, Simons LA, Kavousi M, Vasan RS, Dullaart RPF, Wannamethee SG, Risérus U, Shea S, de Lemos JA, Omland T, Kuulasmaa K, Landmesser U, Blankenberg S; Multinational Cardiovascular Risk Consortium. Application of non-HDL cholesterol for population-based cardiovascular risk stratification: results from the Multinational Cardiovascular Risk Consortium. Lancet. 2019 Dec 14;394(10215):2173-2183. doi: 10.1016/S0140-6736(19)32519-X. Epub 2019 Dec 3. Erratum in: Lancet. 2019 Dec 6 Lancet. 2020 Jan 4;395(10217):32. PMID: 31810609

Ekelund U, Tarp J, Fagerland MW, Johannessen JS, Hansen BH, Jefferis BJ, et al. Joint associations of accelero-meter measured physical activity and sedentary time with all-cause mortality: a harmonised meta-analysis in more than 44 000 middle-aged and older individuals. Br J Sports Med. 2020;54(24):1499-506. PMCID: PMC7719907 DOI: 10.1136/bjsports-2020-103270

Gilani A, Ramsay S, Welsh P, Papacosta O, Lennon L, Whincup P, et al. Vitamin D deficiency is associated with increased risk of postural hypotension in older men: a cross-sectional analysis from The British Regional Heart Study. Br J Gen Pract. 2020;70(suppl 1). DOI: 10.3399/bjgp20X711209

Gilani A, Ramsay SE, Juraschek SP, Papacosta O, Lennon LT, Whincup PH, et al. Associations of the systolic and diastolic components of orthostatic hypotension with markers of cardiovascular risk in older men: A cross-sectional analysis from The British Regional Heart Study. J Clin Hypertens (Greenwich). 2020;22(10):1892-901. PMCID: PMC8029713 DOI: 10.1111/jch.13996

Joshi R, Wannamethee SG, Engmann J, Gaunt T, Lawlor DA, Price J, Papacosta O, Shah T, Tillin T, Chaturvedi N, Kivimaki M, Kuh D, Kumari M, Hughes AD, Casas JP, Humphries S, Hingorani AD, Schmidt AF. Triglyceride-containing lipoprotein sub-fractions and risk of coronary heart disease and stroke: A prospective analysis in 11,560 adults. Eur J Prev Cardiol. 2020 Jan 29:2047487319899621. doi: 10.1177/2047487319899621. [Epub ahead of print] PMID: 31996015

Liljas AEM, Walters K, de Oliveira C, Wannamethee SG, Ramsay SE, Carvalho LA. Self-Reported Sensory Impairments and Changes in Cognitive Performance: A Longitudinal 6-Year Follow-Up Study of English Community-Dwelling Adults Aged 50 Years. J Aging Health. 2020;32(5-6):243-51.PMCID: PMC7221867 DOI: 10.1177/0898264318815391

2019

Aggio D, Papachristou E, Papacosta O, et al. Twenty-Year Trajectories of Physical Activity Types from Midlife to Old Age. Med Sci Sports Exerc 2019; 51(3): 481-9.

Eng, J., Drabwell., Stevenson, F., King, M., Osborn, D., Pitman, A. (2019). Use of Alcohol and Unprescribed Drugs after Suicide Bereavement: Qualitative Study. Int J Environ Res Public Health 16, 4093. https://doi.org/10.3390/ijerph16214093

Jefferis BJ, Parsons TJ, Sartini C, et al. Does total volume of physical activity matter more than pattern for onset of CVD? A prospective cohort study of older British men. Int J Cardiol 2019; 278: 267-72.

Parsons TJ, Papachristou E, Atkins JL, et al. Physical frailty in older men: prospective associations with diet quality and patterns. Age Ageing 2019; 48(3): 355-60.

Rankin NJ, Burgess K, Weidt S, Wannamethee G, Sattar N, Welsh P. High-throughput quantification of carboxymethyl lysine in serum and plasma using high-resolution accurate mass Orbitrap mass spectrometry. Ann Clin Biochem 2019; 56(3): 397-407.

Welsh P, Papacosta O, Ramsay S, et al. High-Sensitivity Troponin T and Incident Heart Failure in Older Men: British Regional Heart Study. J Card Fail 2019; 25(4): 230-7.

Zonoozi S, Ramsay SE, Papacosta O, et al. Chronic kidney disease, cardiovascular risk markers and total mortality in older men: cystatin C versus creatinine. J Epidemiol Community Health 2019; 73(7): 645-51.

2018

Aggio D, Papachristou E, Papacosta O, Lennon L, Ash S, Whincup PH, Wannamethee SG, Jefferis1 BJ. Association Between Twenty-year Trajectories Of Physical Activity From Midlife To Old Age And Biomarkers of CVD: A 20-Year Longitudinal Study Of British Men. American J Epidemiology 2018 Nov 1:187:2315-2323

Aggio D, Papachristou E, Papacosta O, Lennon LT, Ash S, Whincup PH, et al. Trajectories of self-reported physical activity and predictors during the transition to old age: a 20-year cohort study of British men. The International Journal of Behavioral Nutrition and Physical Activity 2018;15(1):14 Epub 2018/02/09

Aggio D, Papacosta O, Lennon LT, Ash S, Whincup PH, Goya Wannamethee S, Jefferis BJ. Tracking of sport and exercise types from midlife to old age: a 20-year cohort study of British men. Eur Rev Aging Phys Act. 2018 Dec 7;15:16.

Hawkesworth S, Silverwood RJ, Armstrong B, Pliakas T, Nanchalal K, Jefferis BJ, et al. Investigating associations between the built environment and physical activity among older people in 20 UK towns. Journal of Epidemiology and Community Health. 2018;72(2):121-31. Epub 2017/11/28

Jefferis BJ, Parsons TJ, Sartini C, Ash S, Lennon LT, Papacosta O, et al. Objectively measured physical activity, sedentary behaviour and all-cause mortality in older men: does volume of activity matter more than pattern of accumulation? British Journal of Sports Medicine. 2018. Epub 2018/02/15

Parsons TJ, Sartini C, Welsh P, Sattar N, Ash S, Lennon LT, et al. Objectively measured physical activity and cardiac biomarkers: A cross sectional population based study in older men International Journal of Cardiology. 2018;254:322-7. Epub 2018/02/07

Parsons TJ, Papachristou E , Atkins JL, Papacosta O, Ash S, Lennon L, Whincup PH, Ramsay SE, Wannamethee SG. Healthier diet quality and dietary patterns are associated with lower risk of mobility limitation in older men. European Journal of Nutrition 2018; Epub Jul 23

Ramsay SE, Papachristou E, Watt RG, Lennon LT, Papacosta AO, Whincup PH, Wannamethee SG. Socioeconomic disadvantage across the life-course and oral health in older age: findings from a longitudinal study of older British men. J Public Health (Oxf). 2018 Apr 19. doi: 10.1093/pubmed/fdy068. [Epub ahead of print]

Sartini C, Tammes P, Hay AD, Preston I, Lasserson D, Whincup PH, et al. Can we identify older people most vulnerable to living in cold homes during winter? Annals of Epidemiology. 2018;28(1):1-7 e3 Epub 2018/02/10

Wannamethee SG, Papacosta O, Lennon L, Whincup PH. Serum magnesium and risk of incident heart failure in older men: The British Regional Heart Study. Eur J Epidemiol. 2018 Apr 17. doi: 10.1007/s10654-018-0388-6. [Epub ahead of print]

Wannamethee SG, Jefferis BJ, Lennon L, Papacosta O, Whincup PH, Hingorani AD. Serum Conjugated Linoleic Acid and Risk of Incident Heart Failure in Older Men: The British Regional Heart Study. Journal of the American Heart Association 2018;7(1).

Wannamethee SG, Papacosta O, Lennon L, Whincup PH. Serum uric acid as a potential marker for heart failure risk in men on antihypertensive treatment: The British Regional Heart Study. International Journal of Cardiology. 2018;252:187-92.

Welsh P, Papacosta O, Ramsay S, Whincup P, McMurray J, WannametheeG, Sattar N. High-Sensitivity Troponin T and Incident Heart Failure in Older Men: British Regional Heart Study. J Card Fail. 2018 Aug 11.

NCD Risk Factor Collaboration (NCD-RisC) Contributions of mean and shape of blood pressure distribution to worldwide trends and variations in raised blood pressure: a pooled analysis of 1018 population-based measurement studies with 88.6 million participants. Int J Epidemiol. 2018 Mar 19. doi: 10.1093/ije/dyy016. [Epub ahead of print]

Prospective Studies Collaboration and Asia Pacific Cohort Studies Collaboration Sex-specific relevance of diabetes to occlusive vascular and other mortality: a collaborative meta-analysis of individual data from 980 793 adults from 68 prospective studies. Lancet Diabetes Endocrinol. 2018 Jul;6(7):538-546. doi: 10.1016/S2213-8587(18)30079-2. Epub 2018 May 8.

Franceschini N, Giambartolomei C, de Vries PS et al. GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes. Nat Commun. 2018 Dec 3;9(1):5141.

2017

Aggio D, Papacosta O, Lennon L, Whincup P, Wannamethee G, Jefferis BJ. Association between physical activity levels in mid-life with physical activity in old age: a 20-year tracking study in a prospective cohort. BMJ Open. 2017;7(8):e017378.

Beaney KE, Smith AJP, Folkersen L, Palmen J, Wannamethee SG, Jefferis BJ, et al. Functional Analysis of the Coronary Heart Disease Risk Locus on Chromosome 21q22. Disease markers. 2017;2017:1096916.

Ellins EA, Smith KE, Lennon LT, Papacosta O, Wannamethee SG, Whincup PH, et al. Arterial pathophysiology and comparison of two devices for pulse wave velocity assessment in elderly men: the British regional heart study. Open Heart. 2017;4(2):e000645.

Fairoozy RH, Cooper J, White J, Giambartolomei C, Folkersen L, Wannamethee SG, et al. Identifying low density lipoprotein cholesterol associated variants in the Annexin A2 (ANXA2) gene. Atherosclerosis. 2017;261:60-8.

Hawkesworth S, Silverwood RJ, Armstrong B, Pliakas T, Nanchahal K, Sartini C, et al. Investigating the importance of the local food environment for fruit and vegetable intake in older men and women in 20 UK towns: a cross-sectional analysis of two national cohorts using novel methods. The International Journal of Behavioral Nutrition and Physical Activity. 2017;14(1):128.

Liljas AEM, Carvalho LA, Papachristou E, De Oliveira C, Wannamethee SG, Ramsay SE, et al. Self-reported vision impairment and incident prefrailty and frailty in English community-dwelling older adults: findings from a 4-year follow-up study. Journal of Epidemiology and Community Health. 2017;71(11):1053-8. Epub 2017/08/12

Liljas AEM, Carvalho LA, Papachristou E, Oliveira C, Wannamethee SG, Ramsay SE, et al. Self-Reported Hearing Impairment and Incident Frailty in English Community-Dwelling Older Adults: A 4-Year Follow-Up Study. Journal of the American Geriatrics Society. 2017;65(5):958-65. Epub 2016/12/20

Papachristou E, Wannamethee SG, Lennon LT, Papacosta O, Whincup PH, Iliffe S, et al. Ability of Self-Reported Frailty Components to Predict Incident Disability, Falls, and All-Cause Mortality: Results From a Population-Based Study of Older British Men. Journal of the American Medical Directors Association. 2017;18(2):152-7.

Parsons TJ, Sartini C, Ash S, Lennon LT, Wannamethee SG, Lee IM, et al. Objectively measured physical activity and kidney function in older men; a cross-sectional population-based study Age and Ageing. 2017;46(6):1010-4

Parsons TJ, Sartini C, Welsh P, Sattar N, Ash S, Lennon LT, et al. Physical Activity, Sedentary Behavior, and Inflammatory and Hemostatic Markers in Men. Medicine and Science in Sports and Exercise. 2017;49(3):459-65.

Ramsay SE, Papachristou E, Watt RG, Tsakos G, Lennon LT, Papacosta AO, et al. Influence of Poor Oral Health on Physical Frailty: A Population-Based Cohort Study of Older British Men Journal of the American Geriatrics Society. 2017.

Sartini C, Barry SJ, Whincup PH, Wannamethee SG, Lowe GD, Jefferis BJ, et al. Relationship between outdoor temperature and cardiovascular disease risk factors in older people. European journal of preventive cardiology. 2017;24(4):349-56.

Sartini C, Morris RW, Whincup PH, Wannamethee SG, Ash S, Lennon L, et al. Association of Maximum Temperature With Sedentary Time in Older British Men. Journal of Physical Activity & Health. 2017;14(4):265-9.

Sartini C, Whincup PH, Wannamethee SG et al. Associations of time of day with cardiovascular disease risk factors measured in older men: results from the British Regional Heart Study. BMJ Open 2017;7(11):e018264

Schutte R, Whincup PH, Papacosta O, Lennon LT, Macfarlane PW, Wannamethee G. Liver enzymes are not directly involved in atrial fibrillation: a prospective cohort study. European Journal of Clinical Investigation. 2017;47(8):583-90

Wannamethee SG, Welsh P, Papacosta O, Ellins EA, Halcox JPJ, Whincup PH, et al. Circulating soluble receptor for advanced glycation end product: Cross-sectional associations with cardiac markers and subclinical vascular disease in older men with and without diabetes. Atherosclerosis. 2017;264:36-43 Epub 2017/08/02

Wannamethee SG, Whincup PH, Papacosta O, Lennon L, Lowe GD. Associations between blood coagulation markers, NT-proBNP and risk of incident heart failure in older men: The British Regional Heart Study. International Journal of Cardiology. 2017;230:567-71.

NCD Risk Factor Collaboration (NCD-RisC). Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128·9 million children, adolescents, and adults. Lancet. 2017 Dec 16;390(10113):2627-2642.

NCD Risk Factor Collaboration (NCD-RisC). Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants. Lancet. 2017 Jan 7;389(10064):37-55.

2016

Aggio DA, Sartini C, Papacosta O, Lennon LT, Ash S, Whincup PH, et al. Cross-sectional associations of objectively measured physical activity and sedentary time with sarcopenia and sarcopenic obesity in older men. Preventive medicine. 2016;91:264-72. Epub 2016/08/31.

Atkins JL, Whincup PH, Morris RW, Lennon LT, Papacosta O, Wannamethee SG. Dietary patterns and the risk of CVD and all-cause mortality in older British men. The British journal of nutrition. 2016;116(7):1246-55. Epub 2016/09/14.

Beaney KE, Cooper JA, McLachlan S, Wannamethee SG, Jefferis BJ, Whincup P, et al. Variant rs10911021 that associates with coronary heart disease in type 2 diabetes, is associated with lower concentrations of circulating HDL cholesterol and large HDL particles but not with amino acids. Cardiovascular diabetology. 2016;15(1):115. Epub 2016/08/24.

Charoen P, Nitsch D, Engmann J, Shah T, White J, Zabaneh D, et al. Mendelian Randomisation study of the influence of eGFR on coronary heart disease. Scientific reports. 2016;6:28514. Epub 2016/06/25.

Jefferis BJ, Parsons TJ, Sartini C, Ash S, Lennon LT, Wannamethee SG, et al. Does duration of physical activity bouts matter for adiposity and metabolic syndrome? A cross-sectional study of older British men. The international journal of behavioural nutrition and physical activity. 2016;13:36. Epub 2016/03/17.

Jefferis BJ, Sartini C, Ash S, Lennon LT, Wannamethee SG, Whincup PH. Validity of questionnaire-based assessment of sedentary behaviour and physical activity in a population-based cohort of older men; comparisons with objectively measured physical activity data. The international journal of behavioural nutrition and physical activity. 2016;13:14. Epub 2016/02/06.

Liljas AE, Carvalho LA, Papachristou E, Oliveira C, Wannamethee SG, Ramsay SE, et al. Self-Reported Hearing Impairment and Incident Frailty in English Community-Dwelling Older Adults: A 4-Year Follow-Up Study. Journal of the American Geriatrics Society. 2016. Epub 2016/12/20.

Liljas AE, Wannamethee SG, Whincup PH, Papacosta O, Walters K, Iliffe S, et al. Hearing impairment and incident disability and all-cause mortality in older British community-dwelling men. Age and ageing. 2016;45(5):662-7. Epub 2016/05/06.

Liljas AE, Wannamethee SG, Whincup PH, Papacosta O, Walters K, Iliffe S, et al. Sensory Impairments and Cardiovascular Disease Incidence and Mortality in Older British Community-Dwelling Men: A 10-Year Follow-Up Study. Journal of the American Geriatrics Society. 2016;64(2):442-4. Epub 2016/02/20.

Liljas AE, Wannamethee SG, Whincup PH, Papacosta O, Walters K, Iliffe S, et al. Socio-demographic characteristics, lifestyle factors and burden of morbidity associated with self-reported hearing and vision impairments in older British community-dwelling men: a cross-sectional study. J Public Health (Oxf). 2016;38(2):e21-8. Epub 2015/07/17.

Morris RW, Cooper JA, Shah T, Wong A, Drenos F, Engmann J, et al. Marginal role for 53 common genetic variants in cardiovascular disease prediction. Heart. 2016;102(20):1640-7. Epub 2016/07/02.

Papachristou E, Ramsay SE, Papacosta O, Lennon LT, Iliffe S, Whincup PH, et al. The Test Your Memory cognitive screening tool: sociodemographic and cardiometabolic risk correlates in a population-based study of older British men. International journal of geriatric psychiatry. 2016;31(6):666-75. Epub 2015/10/23.

Parsons TJ, Sartini C, Ellins EA, Halcox JP, Smith KE, Ash S, et al. Objectively measured physical activity, sedentary time and subclinical vascular disease: Cross-sectional study in older British men. Preventive medicine. 2016;89:194-9. Epub 2016/06/05.

Parsons TJ, Sartini C, Ellins EA, Halcox JP, Smith KE, Ash S, et al. Objectively measured physical activity and sedentary behaviour and ankle brachial index: Cross-sectional and longitudinal associations in older men. Atherosclerosis. 2016;247:28-34. Epub 2016/02/09.

Sartini C, Barry SJ, Wannamethee SG, Whincup PH, Lennon L, Ford I, et al. Effect of cold spells and their modifiers on cardiovascular disease events: Evidence from two prospective studies. International journal of cardiology. 2016;218:275-83. Epub 2016/05/31.

Sartini C, Morris RW, Whincup PH, Wannamethee SG, Ash S, Lennon L, et al. Association of Maximum Temperature With Sedentary Time in Older British Men. Journal of physical activity & health. 2016:1-18. Epub 2016/12/30.

Wannamethee SG, Papacosta O, Lennon L, Whincup PH. Self-Reported Sleep Duration, Napping, and Incident Heart Failure: Prospective Associations in the British Regional Heart Study. Journal of the American Geriatrics Society. 2016;64(9):1845-50. Epub 2016/06/29.

Wannamethee SG, Shaper AG, Lennon L, Papacosta O, Whincup P. Mild hyponatremia, hypernatremia and incident cardiovascular disease and mortality in older men: A population-based cohort study. Nutrition, metabolism, and cardiovascular diseases : NMCD. 2016;26(1):12-9. Epub 2015/08/25.

Wannamethee SG, Shaper AG, Papacosta O, Lennon L, Welsh P, Whincup PH. Lung function and airway obstruction: associations with circulating markers of cardiac function and incident heart failure in older men-the British Regional Heart Study. Thorax. 2016;71(6):526-34. Epub 2016/01/27.

Wannamethee SG, Welsh P, Lennon L, Papacosta O, Whincup PH, Sattar N. Copeptin and the risk of incident stroke, CHD and cardiovascular mortality in older men with and without diabetes: The British Regional Heart Study. Diabetologia. 2016;59(9):1904-12. Epub 2016/06/18.

Welsh P, Hart C, Papacosta O, Preiss D, McConnachie A, Murray H, et al. Prediction of Cardiovascular Disease Risk by Cardiac Biomarkers in 2 United Kingdom Cohort Studies: Does Utility Depend on Risk Thresholds For Treatment? Hypertension. 2016;67(2):309-15. Epub 2015/12/17.

White J, Sofat R, Hemani G, Shah T, Engmann J, Dale C, et al. Plasma urate concentration and risk of coronary heart disease: a Mendelian randomisation analysis. The lancet Diabetes & endocrinology. 2016;4(4):327-36. Epub 2016/01/20.

2015

Atkins JL, Ramsay SE, Whincup PH, Morris RW, Lennon LT, Wannamethee SG. Diet quality in older age: the influence of childhood and adult socio-economic circumstances. The British journal of nutrition. 2015;113(9):1441-52. Epub 2015/04/02.

Herbert, A., Gilbert, R., Gonzalez-Izquierdo, A., Pitman, A., Li, L. (2015). Ten-year risks of death and emergency re-admission in adolescents hospitalised with violent, drug- or alcohol-related, or self-inflicted injury: a population-based analysis. PLoS MEdicine 12(12): e1001931. DOI: 10.1371/journal.pmed.1001931 (runner-up in UCL Excellence in Health Research Prize Dr Annie Herbert)

Jefferis BJ, Merom D, Sartini C, Wannamethee SG, Ash S, Lennon LT, et al. Physical Activity and Falls in Older Men: The Critical Role of Mobility Limitations. Medicine and science in sports and exercise. 2015;47(10):2119-28. Epub 2015/02/11.

Jefferis BJ, Sartini C, Ash S, Lennon LT, Wannamethee SG, Lee IM, et al. Trajectories of objectively measured physical activity in free-living older men. Medicine and science in sports and exercise. 2015;47(2):343-9. Epub 2014/07/06.

Jefferis BJ, Sartini C, Shiroma E, Whincup PH, Wannamethee SG, Lee IM. Duration and breaks in sedentary behaviour: accelerometer data from 1566 community-dwelling older men (British Regional Heart Study). British journal of sports medicine. 2015;49(24):1591-4. Epub 2014/09/19.

Lennon LT, Ramsay SE, Papacosta O, Shaper AG, Wannamethee SG, Whincup PH. Cohort Profile Update: The British Regional Heart Study 1978-2014: 35 years follow-up of cardiovascular disease and ageing. International journal of epidemiology. 2015;44(3):826-g. Epub 2015/08/02.

Linneberg A, Jacobsen RK, Skaaby T, Taylor AE, Fluharty ME, Jeppesen JL, et al. Effect of Smoking on Blood Pressure and Resting Heart Rate: A Mendelian Randomization Meta-Analysis in the CARTA Consortium. Circulation Cardiovascular genetics. 2015;8(6):832-41. Epub 2015/11/06.

Morris RW, Taylor AE, Fluharty ME, Bjorngaard JH, Asvold BO, Elvestad Gabrielsen M, et al. Heavier smoking may lead to a relative increase in waist circumference: evidence for a causal relationship from a Mendelian randomisation meta-analysis. The CARTA consortium. BMJ open. 2015;5(8):e008808. Epub 2015/08/13.

Nuesch E, Dale C, Palmer TM, White J, Keating BJ, van Iperen EP, et al. Adult height, coronary heart disease and stroke: a multi-locus Mendelian randomization meta-analysis. International journal of epidemiology. 2015. Epub 2015/05/17.

Owen CG, Kapetanakis VV, Rudnicka AR, Wathern AK, Lennon L, Papacosta O, et al. Body mass index in early and middle adult life: prospective associations with myocardial infarction, stroke and diabetes over a 30-year period: the British Regional Heart Study. BMJ open. 2015;5(9):e008105. Epub 2015/09/17.

Papachristou E, Ramsay SE, Lennon LT, Papacosta O, Iliffe S, Whincup PH, et al. The relationships between body composition characteristics and cognitive functioning in a population-based sample of older British men. BMC geriatrics. 2015;15:172. Epub 2015/12/23.

Ramsay SE, Arianayagam DS, Whincup PH, Lennon LT, Cryer J, Papacosta AO, et al. Cardiovascular risk profile and frailty in a population-based study of older British men. Heart. 2015;101(8):616-22. Epub 2014/12/07.

Ramsay SE, Morris RW, Whincup PH, Subramanian SV, Papacosta AO, Lennon LT, et al. The influence of neighbourhood-level socioeconomic deprivation on cardiovascular disease mortality in older age: longitudinal multilevel analyses from a cohort of older British men. Journal of epidemiology and community health. 2015;69(12):1224-31. Epub 2015/08/20.

Ramsay SE, Whincup PH, Watt RG, Tsakos G, Papacosta AO, Lennon LT, et al. Burden of poor oral health in older age: findings from a population-based study of older British men. BMJ open. 2015;5(12):e009476. Epub 2015/12/31.

Sartini C, Wannamethee SG, Iliffe S, Morris RW, Ash S, Lennon L, et al. Diurnal patterns of objectively measured physical activity and sedentary behaviour in older men. BMC public health. 2015;15:609. Epub 2015/07/05.

Swerdlow DI, Preiss D, Kuchenbaecker KB, Holmes MV, Engmann JE, Shah T, et al. HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials. Lancet. 2015;385(9965):351-61. Epub 2014/09/30.

Talmud PJ, Cooper JA, Morris RW, Dudbridge F, Shah T, Engmann J, et al. Sixty-five common genetic variants and prediction of type 2 diabetes. Diabetes. 2015;64(5):1830-40. Epub 2014/12/06.

Wade KH, Forouhi NG, Cook DG, Johnson P, McConnachie A, Morris RW, et al. Variation in the SLC23A1 gene does not influence cardiometabolic outcomes to the extent expected given its association with L-ascorbic acid. The American journal of clinical nutrition. 2015;101(1):202-9. Epub 2014/12/21.

Wannamethee SG, Atkins JL. Muscle loss and obesity: the health implications of sarcopenia and sarcopenic obesity. The Proceedings of the Nutrition Society. 2015;74(4):405-12. Epub 2015/04/29.

Wannamethee SG, Welsh P, Papacosta O, Lennon L, Whincup PH, Sattar N. Copeptin, Insulin Resistance, and Risk of Incident Diabetes in Older Men. The Journal of clinical endocrinology and metabolism. 2015;100(9):3332-9. Epub 2015/07/15.

Wannamethee SG, Whincup PH, Lennon L, Papacosta O, Shaper AG. Alcohol consumption and risk of incident heart failure in older men: a prospective cohort study. Open heart. 2015;2(1):e000266. Epub 2015/08/21.

2014

Atkins JL, Whincup PH, Morris RW, Lennon LT, Papacosta O, Wannamethee SG. High diet quality is associated with a lower risk of cardiovascular disease and all-cause mortality in older men. J Nutr. 2014 May;144(5):673-80. doi: 10.3945/jn.113.186486. Epub 2014 Feb 26.

Atkins JL, Whincup PH, Morris RW, Lennon LT, Papacosta O, Wannamethee SG. Sarcopenic obesity and risk of cardiovascular disease and mortality: a population-based cohort study of older men. Journal of the American Geriatrics Society. J Am Geriatr Soc. 2014 Feb;62(2):253-60. doi: 10.1111/jgs.12652. Epub 2014 Jan 15.

Atkins JL, Whincup PH, Morris RW, Wannamethee SG. Low muscle mass in older men: the role of lifestyle, diet and cardiovascular risk factors. J Nutr Health Aging. 2014 Jan;18(1):26-33. doi: 10.1007/s12603-013-0336-9.

Jefferis BJ, Whincup PH, Papacosta O, Wannamethee SG. Protective effect of time spent walking on risk of stroke in older men. Stroke 2014; 45(1):194-9.

Jefferis BJ, Sartini C, Lee IM, Choi M, Amuzu A, Gutierrez C, Casas JP, Ash S, Lennnon LT, Wannamethee SG, Whincup PH. Adherence to physical activity guidelines in older adults, using objectively measured physical activity in a population-based study. BMC Public Health. 2014 Apr 19;14(1):382. doi: 10.1186/1471-2458-14-382.

Jefferis BJ, Whincup PH, Lennon LT, Papacosta O, Goya Wannamethee S.

Physical activity in older men: longitudinal associations with inflammatory and hemostatic biomarkers, N-terminal pro-brain natriuretic Peptide, and onset of coronary heart disease and mortality. J Am Geriatr Soc. 2014 Apr;62(4):599-606. doi: 10.1111/jgs.12748. Epub 2014 Mar 17.

Ramsay SE, Whincup PH, Papacosta O, Morris R, Lennon L, Wannamethee SG. Inequalities in heart failure in older men: prospective associations between socioeconomic measures and heart failure incidence in a 10-year follow-up study. Eur Heart J. 2014 Feb;35(7):442-7. doi: 10.1093/eurheartj/eht449. Epub 2013 Oct 18.

Wannamethee SG, Welsh P, Whincup PH, Lennon L, Papacosta O, Sattar N. NT-proBNP but not copeptin improves prediction of heart failure over other routine clinical risk parameters in older men with and without cardiovascular disease: population based study. Eur J Heart Fail. 2014 Jan;16(1):25-32. doi: 10.1093/eurjhf/hft124. Epub 2013 Dec 3.

Wannamethee SG, Shaper AG, Whincup PH, Lennon L, Papacosta O, Sattar N. The obesity paradox in men with coronary heart disease and heart failure: the role of muscle mass and leptin. Int J Cardiol. 2014 Jan 15;171(1):49-55. doi: 10.1016/j.ijcard.2013.11.043. Epub 2013 Nov 23.

2013

Holmes MV, Simon T, Exeter HJ, Folkersen L, Asselbergs FW, Guardiola M, Cooper JA, Palmen J, Hubacek JA, Carruthers KF, Horne BD, Brunisholz KD, Mega JL, van Iperen EP, Li M, Leusink M, Trompet S, Verschuren JJ, et al. Secretory Phospholipase A2-IIA and Cardiovascular Disease: a Mendelian randomization study. J Am Coll Cardiol. 2013 Jul 19 S0735-1097(13)02778-2. PMID: 23916927

Jefferis BJ, Whincup PH, Welsh P, Wannamethee SG, Rumley A, Ebrahim S, Lawlor DA,Lowe GD. Prospective study of IL-18 and risk of MI and stroke in men and women aged 60-79 years: a nested case-control study. Cytokine. 2013 Feb;61(2):513-20.

Khan TA, Shah T, Prieto D, Zhang W, Price J, Fowkes GR, Cooper J, Talmud PJ, Humphries SE, Sundstrom J, Hubacek JA, Ebrahim S, Lawlor DA, Ben-Shlomo Y, Abdollahi MR, Slooter AJ, Szolnoki Z, Sandhu M, Wareham N, Frikke-Schmidt R, Tybjærg-Hansen A, Fillenbaum G, Heijmans BT, Katsuya T, Gromadzka G, Singleton A, Ferrucci L, Hardy J, Worrall B, Rich SS, Matarin M, Whittaker J, Gaunt TR, Whincup P, Morris R, Deanfield J, Donald A, Davey Smith G, Kivimaki M, Kumari M, Smeeth L, Khaw KT, Nalls M, Meschia J, Sun K, Hui R, Day I, Hingorani AD, Casas JP. Apolipoprotein E genotype, cardiovascular biomarkers and risk of stroke: systematic review and meta-analysis of 14,015 stroke cases and pooled analysis of primary biomarker data from up to 60,883 individuals. Int J Epidemiol. 2013 Apr;42(2):475-92. PMID: 23569189

Rutter MK, Sattar N, Tajar A, O'Neill TW, Lee DM, Bartfai G et al. Epidemiological evidence against a role for C-reactive protein causing leptin resistance. Eur J Endocrinol 2013; 168(1):101-106.

Singh GM, Danaei G, Farzadfar F, Stevens GA, Woodward M, Wormser D, Kaptoge S, Whitlock G, Qiao Q, Lewington S, Di Angelantonio E, Vander Hoorn S, Lawes CM, Ali MK, Mozaffarian D, Ezzati M; Global Burden of Metabolic Risk Factors of Chronic Diseases Collaborating Group; Asia-Pacific Cohort Studies Collaboration (APCSC); Diabetes Epidemiology: Collaborative analysis of Diagnostic criteria in Europe (DECODE); Emerging Risk Factor Collaboration (ERFC); Prospective Studies Collaboration (PSC). The age-specific quantitative effects of metabolic risk factors on cardiovascular diseases and diabetes: a pooled analysis. PLoS One. 2013 Jul 30;8(7):e65174. PMID: 23935815

Shah T, Engmann J, Dale C, Shah S, White J, Giambartolomei C, McLachlan S, Zabaneh D, Cavadino A, Finan C, Wong A, Amuzu A, Ong K, Gaunt T, Holmes MV, Warren H, Davies TL, Drenos F, Cooper J, Sofat R, Caulfield M, Ebrahim S, Lawlor DA, Talmud PJ, Humphries SE, Power C, Hypponen E, Richards M, Hardy R, Kuh D, Wareham N, Ben-Shlomo Y, Day IN, Whincup P, Morris R, Strachan MW, Price J, Kumari M, Kivimaki M, Plagnol V, Dudbridge F, Whittaker JC, Casas JP, Hingorani AD; UCLEB Consortium. Population Genomics of Cardiometabolic Traits: Design of the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) Consortium. PLoS One. 2013 Aug 20;8(8):e71345. PMID: 23977022

Wannamethee SG, Sattar N, Papcosta O, Lennon L, Whincup PH. Alkaline phosphatase, serum phosphate, and incident cardiovascular disease and total mortality in older men. Arterioscler Thromb Vasc Biol 2013; 33(5):1070-1076.

Wannamethee SG, Shaper AG, Whincup PH, Lennon L, Sattar N. Adiposity, adipokines, and risk of incident stroke in older men. Stroke 2013; 44(1):3-8.

Wannamethee SG, Bruckdorfer KR, Shaper AG, Papacosta O, Lennon L, Whincup PH. Plasma vitamin C, but not vitamin E, is associated with reduced risk of heart failure in older men. Circ Heart Fail. 2013 Jul;6(4):647-54.

Wannamethee SG. Significance of frequency patterns in 'moderate' drinkers for low-risk drinking guidelines. Addiction. 2013 Sep;108(9):1545-7.

2012

Angelakopoulou A, Shah T, Sofat R, Shah S, Berry DJ, Cooper J et al. Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration. Eur Heart J 2012; 33(3):393-407.

Di AE, Gao P, Pennells L, Kaptoge S, Caslake M, Thompson A et al. Lipid-related markers and cardiovascular disease prediction. JAMA 2012; 307(23):2499-2506.

Ghebre MA, Wannamethee SG, Rumley A, Whincup PH, Lowe GD, Morris RW. Prospective study of seasonal patterns in hemostatic factors in older men and their relation to excess winter coronary heart disease deaths. J Thromb Haemost 2012; 10(3):352-358.

Emerging Risk Factors Collaboration. Adult height and the risk of cause-specific death and vascular morbidity in 1 million people: individual participant meta-analysis. Int J Epidemiol 2012; 41(5):1419-1433.

Hingorani AD, Sofat R, Morris RW, Whincup P, Lowe GD, Mindell J et al. Is it important to measure or reduce C-reactive protein in people at risk of cardiovascular disease? Eur Heart J 2012; 33(18):2258-2264

Interleukin-6 Receptor Mendelian Randomisation Analysis (IL6R MR) Consortium, Hingorani AD, Casas JP. The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis. Lancet 2012; 379(9822):1214-1224.

Jefferis BJ, Whincup PH, Lennon L, Wannamethee SG. Longitudinal associations between changes in physical activity and onset of type 2 diabetes in older British men: the influence of adiposity. Diabetes Care 2012; 35(9):1876-1883.

Kaptoge S, Di AE, Pennells L, Wood AM, White IR, Gao P et al. C-reactive protein, fibrinogen, and cardiovascular disease prediction. N Engl J Med 2012; 367(14):1310-1320.

Munafo MR, Timofeeva MN, Morris RW, Prieto-Merino D, Sattar N, Brennan P et al. Association between genetic variants on chromosome 15q25 locus and objective measures of tobacco exposure. J Natl Cancer Inst 2012; 104(10):740-748.

Rutter MK, Sattar N, Tajar A, O'Neill TW, Lee DM, Bartfai G et al. Epidemiological evidence against a role for C-reactive protein causing leptin resistance. Eur J Endocrinol 2013; 168(1):101-106.

Sarwar N, Butterworth AS, Freitag DF, Gregson J, Willeit P, Gorman DN et al. Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies. Lancet 2012; 379(9822):1205-1213.

Wannamethee SG, Whincup PH, Lennon L, Rumley A, Lowe GD. Fibrin D-dimer, tissue-type plasminogen activator, von Willebrand factor, and risk of incident stroke in older men. Stroke 2012; 43(5):1206-1211.

Wannamethee SG, Papacosta O, Lawlor DA, Whincup PH, Lowe GD, Ebrahim S et al. Do women exhibit greater differences in established and novel risk factors between diabetes and non-diabetes than men? The British Regional Heart Study and British Women's Heart Health Study. Diabetologia 2012; 55(1):80-87.

Wannamethee SG, Whincup PH, Shaper AG, Lennon L, Sattar N. Gamma-glutamyltransferase, hepatic enzymes, and risk of incident heart failure in older men. Arterioscler Thromb Vasc Biol 2012; 32(3):830-835.

2011

Angelakopoulou A, Shah T, Sofat R, Shah S, Berry DJ, Cooper J et al. Comparative analysis of genome-wide-association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration. Eur Heart J 2011 July 30.

Artigas MS, Loth DW, Wain LV, Gharib SA, Obeidat M, Tang W et al. Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. Nat Genet 2011;43(11):1082-90.

Dudina A, Cooney MT, Bacquer DD, Backer GD, Ducimetiere P, Jousilahti P et al. Relationships between body mass index, cardiovascular mortality, and risk factors: a report from the SCORE investigators. Eur J Cardiovasc Prev Rehabil 2011 October;18(5):731-42.

Ehret GB, Munroe PB, Rice KM, Bochud M, Johnson AD, Chasman DI et al. Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature 2011 October 6;478(7367):103-9.

Freathy RM, Kazeem GR, Morris RW, Johnson PC, Paternoster L, Ebrahim S et al. Genetic variation at CHRNA5-CHRNA3-CHRNB4 interacts with smoking status to influence body mass index. Int J Epidemiol 2011 May 18.

Hardoon SL, Morris RW, Whincup PH, Shipley MJ, Britton AR, Masset G et al. Rising adiposity curbing decline in the incidence of myocardial infarction: 20-year follow-up of British men and women in the Whitehall II cohort. Eur Heart J 2011 June 8.

Hardoon SL, Whincup PH, Petersen I, Capewell S, Morris RW. Trends in longer-term survival following an acute myocardial infarction and prescribing of evidenced-based medications in primary care in the UK from 1991: a longitudinal population-based study. J Epidemiol Community Health 2011 September;65(9):770-4.

Jefferis BJ, Papacosta O, Owen CG, Wannamethee SG, Humphries SE, Woodward M et al. Interleukin 18 and coronary heart disease: prospective study and systematic review. Atherosclerosis 2011 July;217(1):227-33.

Jefferis BJ, Whincup PH, Welsh P, Wannamethee SG, Rumley A, Lawlor DA et al. Prospective study of circulating soluble CD40 ligand concentrations and the incidence of cardiovascular disease in a nested prospective case-control study of older men and women. J Thromb Haemost 2011 August;9(8):1452-9.

Johnson T, Gaunt TR, Newhouse SJ, Padmanabhan S, Tomaszewski M, Kumari M et al. Blood Pressure Loci Identified with a Gene-Centric Array. Am J Hum Genet 2011 November 16.

Jones IR, Papacosta O, Whincup PH, Wannamethee SG, Morris RW. Class and lifestyle 'lock-in' among middle-aged and older men: a Multiple Correspondence Analysis of the British Regional Heart Study. Sociol Health Illn 2011 March;33(3):399-419.

Lawlor DA, Kim L, Morris R, Amuzu A, Whincup P, Ebrahim S. Survival with treated and well-controlled blood pressure: findings from a prospective cohort study. PLoS One 2011;6(4):e17792.

Ramsay SE, Whincup PH, Lennon LT, Morris RW, Wannamethee SG. Longitudinal associations of socioeconomic position in childhood and adulthood with decline in lung function over 20 years: results from a population-based cohort of British men. Thorax 2011 December;66(12):1058-64.

Ramsay SE, Morris RW, Whincup PH, Papacosta AO, Thomas MC, Wannamethee SG. Prediction of coronary heart disease risk by Framingham and SCORE risk assessments varies by socioeconomic position: results from a study in British men. Eur J Cardiovasc Prev Rehabil 2011 April;18(2):186-93.

Ramsay SE, Whincup PH, Hardoon SL, Lennon LT, Morris RW, Wannamethee SG. Social class differences in secular trends in established coronary risk factors over 20 years: a cohort study of British men from 1978-80 to 1998-2000. PLoS One 2011;6(5):e19742.

Soler AM, Wain LV, Repapi E, Obeidat M, Sayers I, Burton PR et al. Effect of five genetic variants associated with lung function on the risk of chronic obstructive lung disease, and their joint effects on lung function. Am J Respir Crit Care Med 2011 October 1;184(7):786-95.

Wannamethee SG, Welsh P, Whincup PH, Sawar N, Thomas MC, Gudnarsson V et al. High adiponectin and increased risk of cardiovascular disease and mortality in asymptomatic older men: does NT-proBNP help to explain this association? Eur J Cardiovasc Prev Rehabil 2011 February;18(1):65-71.

Wannamethee SG, Shaper AG, Whincup PH, Lennon L, Sattar N. Impact of diabetes on cardiovascular disease risk and all-cause mortality in older men: influence of age at onset, diabetes duration, and established and novel risk factors. Arch Intern Med 2011 March 14;171(5):404-10.

Wannamethee SG, Welsh P, Lowe GD, Gudnason V, Di AE, Lennon L et al. N-terminal pro-brain natriuretic Peptide is a more useful predictor of cardiovascular disease risk than C-reactive protein in older men with and without pre-existing cardiovascular disease. J Am Coll Cardiol 2011 June 28;58(1):56-64.

Wannamethee SG, Shaper AG, Whincup PH, Lennon L, Sattar N. Obesity and risk of incident heart failure in older men with and without pre-existing coronary heart disease: does leptin have a role? J Am Coll Cardiol 2011 October 25;58(18):1870-7.

Wannamethee SG, Papacosta O, Whincup PH, Thomas MC, Carson C, Lawlor DA et al. The potential for a two-stage diabetes risk algorithm combining non-laboratory-based scores with subsequent routine non-fasting blood tests: results from prospective studies in older men and women. Diabet Med 2011 January;28(1):23-30.

Zabaneh D, Gaunt TR, Kumari M, Drenos F, Shah S, Berry D et al. Genetic variants associated with Von Willebrand factor levels in healthy men and women identified using the HumanCVD BeadChip. Ann Hum Genet 2011 July;75(4):456-67.

2010

Hardoon SL, Morris RW, Thomas MC, Wannamethee SG, Lennon LT, Whincup PH. Is the recent rise in type 2 diabetes incidence from 1984 to 2007 explained by the trend in increasing BMI?: evidence from a prospective study of British men. Diabetes Care 2010;33(7):1494-6.

Hardoon SL, Whincup PH, Wannamethee SG, Lennon LT, Capewell S, Morris RW. Assessing the impact of medication use on trends in major coronary risk factors in older British men: a cohort study. Eur J Cardiovasc Prev Rehabil 2010;17(5):502-8.

Jefferis BJ, Lawlor DA, Ebrahim S, Wannamethee SG, Feyerabend C, Doig M, McMeekin L, Cook DG, Whincup PH. Cotinine-assessed second-hand smoke exposure and risk of cardiovascular disease in older adults. Heart. 2010;96(11):854-9.

Ramsay S, Morris R, Whincup P, Papacosta A, Thomas M, Wannamethee S. Prediction of coronary heart disease risk by Framingham and SCORE risk assessments varies by socioeconomic position: results from a population-based study in British men. Eur J Cardiovasc Prev Rehab. In Press.

Shaper AG. Alcohol consumption decreases with the development of disease. AIM (Alcohol in Moderation) Digest Online. 2010;29(2):9.

Taylor AE, Ebrahim S, Ben-Shlomo Y, Martin RM, Whincup PH, Yarnell JW, Wannamethee SG, Lawlor DA. Comparison of the associations of body mass index and measures of central adiposity and fat mass with coronary heart disease, diabetes, and all-cause mortality: a study using data from 4 UK cohorts. Am J Clin Nutr. 2010 Mar;91(3):547-56. Epub 2010 Jan 20.

Timpson NJ, Forouhi NG, Brion MJ, Harbord RM, Cook DG, Johnson P, McConnachie A, Morris RW, Rodriguez S, Luan J, et al. Genetic variation at the SLC23A1 locus is associated with circulating concentrations of L-ascorbic acid (vitamin C): evidence from 5 independent studies with > 15,000 participants. Am J Clin Nutrition 2010;92(2):375-382.

Wannamethee SG, Shaper AG, Rumley A, Sattar N, Whincup PH, Thomas MC, Lowe GD. Lung function and risk of type 2 diabetes and fatal and nonfatal major coronary heart disease events: possible associations with inflammation. Diabetes Care. 2010;33(9):1990-6.

Wannamethee SG, Shaper AG. Cigarette smoking and serum liver enzymes: the role of alcohol and inflammation. Ann Clin Biochem. 2010;47(Pt 4):321-6.

Wannamethee SG, Welsh P, Whincup PH, Sawar N, Thomas MC, Gudnarsson V, Sattar N. High adiponectin and increased risk of cardiovascular disease and mortality in asymptomatic older men: does NT-proBNP help to explain this association? Eur J Cardiovasc Prev Rehabil. 2010 May 25th epub ahead of publication.

Wannamethee SG, Papacosta O, Whincup PH, Carson C, Thomas MC, Lawlor DA, Ebrahim S, Sattar N. Assessing prediction of diabetes in older adults using different adiposity measures: a 7 year prospective study in 6,923 older men and women. Diabetologia. 2010;53(5):890-8.

Wannamethee SG, Shaper AG, Whincup PH, Lennon L, Sattar N. Type 2 diabetes in older age and risk of coronary heart disease and all cause mortality: impact of age at onset, diabetes duration and established and novel risk factors. Arch Intern Med. In press.

Emerging Risk Factors Collaboration, Sarwar N, Gao P, Seshasai SR, Gobin R, Kaptoge S, Di Angelantonio E, Ingelsson E, Lawlor DA, Selvin E, Stampfer M, Stehouwer CD, Lewington S, Pennells L, Thompson A, Sattar N, White IR, Ray KK, Danesh J. Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies. Lancet. 2010;375(9733):2215-22.

Emerging Risk Factors Collaboration, Thompson S, Kaptoge S, White I, Wood A, Perry P, Danesh J. Statistical methods for the time-to-event analysis of individual participant data from multiple epidemiological studies. Int J Epidemiol. 2010;39(5):1345-59.

Emerging Risk Factors Collaboration, Kaptoge S, Di Angelantonio E, Lowe G, Pepys MB, Thompson SG, Collins R, Danesh J. C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: an individual participant meta-analysis. Lancet. 2010;375(9709):132-40.

Triglyceride Coronary Disease Genetics Consortium and Emerging Risk Factors Collaboration, Sarwar N, Sandhu MS, Ricketts SL, Butterworth AS, Di Angelantonio E, Boekholdt SM, Ouwehand W, Watkins H, Samani NJ, et al. Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies. Lancet. 2010;375(9726):1634-1639.

2009

Emerging Risk Factors Collaboration, Di Angelantonio E, Sarwar N, Perry P, Kaptoge S, Kausik KR, Thompson A, Wood AM, Lewington S, Sattar N, Packard CJ, Collins R,.Thompson SG, Danesh J. Major Lipids, Apolipoproteins, and Risk of Vascular Disease. JAMA. 2009;302(18):1993-2000.

Jefferis BJ, Whincup PH, Welsh P, Wannamethee SG, Rumley A, Lennon LT, Thomson AG, Carson C, Ebrahim S, Lowe GDO. Circulating TNFa? levels in older men and women do not show independent prospective relations with MI or stroke. Atherosclerosis. 2009; 205(1): 302-308

Jefferis BJ, Lowe GD, Welsh P, Rumley A, Lawlor DA, Ebrahim S, Carson C, Doig M, Feyerabend C, McMeekin L, Wannamethee SG, Cook DG, Whincup PH. Secondhand smoke (SHS) exposure is associated with circulating markers of inflammation and endothelial function in adult men and women. Atherosclerosis. In Press, Available online 30 Jul 2009 [Epub ahead of print]

Jefferis BJ, Whincup PH, Welsh P, Wannamethee SG, Rumley A, Lennon LT, Thomson AG, Lawlor D, Carson C, Ebrahim S, Lowe GDO Prospective study of matrix metalloproteinase-9 and risk of myocardial infarction and stroke in older men and womenAtherosclerosis, In Press, Available online 19 August 2009 [Epub ahead of print]

Jefferis BJ, Thomson AG, Lennon LT, Feyerabend C, Doig M, McMeekin L, Wannamethee SG, Cook DG, Whincup PH. Changes in environmental tobacco smoke (ETS) exposure over a 20 year period: cross-sectional and longitudinal analyses. Addiction. 2009 Mar;104(3):496-503.

Ramsay SE, Morris RW, Whincup PH, Papacosta O, Rumley A, Lennon L, Lowe GDO, Wannamethee SG. Socioeconomic inequalities in coronary heart disease risk in older age: contribution of established and novel coronary risk factors. Journal of Thrombosis and Haemostasis. 2009;7:1779-1786

Sattar N, Wannamethee G, Sarwar N, Chernova J, Lawlor DA, Kelly A, Wallace AM, Danesh J, Whincup PH. Leptin and coronary heart disease: prospective study and systematic review. Journal of the American College of Cardiology. 2009;53(2):167-75.

Thomas MC, Hardoon SL, Papacosta AO, Morris RW, Wannamethee SG, Sloggett A, Whincup PH. Evidence of an accelerating increase in prevalence of diagnosed Type 2 diabetes in British men, 1978-2005. Diabetic Medicine. 2009;26(8):766-72.

Wannamethee SG. Interventions to increase adiponectin may be associated with increased coronary heart disease in older adults. Future Cardiol. 2009;5(1):19-22.

Wannamethee SG, Whincup PH, Shaper AG, Rumley A, Lennon LT, Lowe GDO. Circulating inflammatory and hemostatic biomarkers are associated with risk of myocardial infarction and coronary death, but not angina pectoris, in older men. J Thrombosis and Haemostasis. 2009;7(10):1605-11.

Wannamethee SG, Whincup PH, Thomas MC, Sattar N. Associations between dietary fibre and inflammation, hepatic function, and risk of type 2 diabetes in older men: potential mechanisms for the benefits of fibre on diabetes risk. Diabetes Care. 2009;32(10):1823-5.

Prospective Studies Collaboration: Whitlock G, Lewington S, Sherliker P, Clarke R, Emberson J, Halsey J, Qizilbash N, Collins R, Peto R. Body-mass index and cause-specific mortality in 900 000 adults: collaborative analyses of 57 prospective studies. Lancet 2009 28;373(9669):1083-96.

2008

CRP CHD Genetics Collaboration. Collaborative pooled analysis of data on C-reactive protein gene variants and coronary disease: judging causality by Mendelian randomisation. Eur J Epidemiol. 2008;23(8):531-40.

Danesh J, Kaptoge S, Mann AG, Sarwar N, Wood A, Angleman S, Wensley F, Higgins JPT, Lennon L, Eiriksdottir G, Rumley A, Whincup PH, Lowe GDO, Gudnason V. Long-term interleukin-6 levels and subsequent risk of coronary heart disease: Two new prospective studies and a systematic review. PLoS Medicine. 5(4): e78. doi:10.1371/journal.pmed.0050078

Hardoon SL, Whincup PH, Lennon LT, Wannamethee SG, Capewell S, Morris RW. How much of the recent decline in the incidence of myocardial infarction in British men can be explained by changes in cardiovascular risk factors? Evidence from a prospective population based study. Circulation. 2008;117:598-604

Morris RW, Walker MK, Lennon LT, Shaper AG, Whincup PH. Hard drinking water does not protect against cardiovascular disease. New evidence from the British Regional Heart Study. European Journal of Cardiovascular Prevention and Rehabilitation. 2008;15(2):185-189.

Morris RW, Wannamethee G, Lennon LT, Thomas MC, Whincup PH. Do socioeconomic characteristics of neighbourhood of residence independently influence incidence of coronary heart disease and all-cause mortality in older British men? European Journal of Cardiovascular Prevention and Rehabilitation. 2008; 15(1):19-25.

Ramsay SE, Lowe GDO, Whincup PH, Rumley A, Morris RW, Wannamethee SG. Relationships of inflammatory and haemostatic markers with social class: results from a population-based study of older men. Atherosclerosis 2008; 197(2): 654-661

Ramsay SE, Morris RW, Whincup PH, Lennon LT, Wannamethee SG. Are social inequalities in mortality in Britain narrowing? Time trends from 1978 to 2005 in a population-based study of older men. Journal of Epidemiology and Community Health. 2008;62:75-80.

Ramsay SE, Whincup PH, Morris RW, Lennon LT; Wannamethee SG. Extent of Social Inequalities in Disability in the Elderly: Results from a Population-based Study of British Men Annals of Epidemiology 2008 ;18(12):896-903.

Ramsay SE, Ebrahim S; Whincup PH; Papacosta O; Morris RW; Lennon LT; Wannamethee SG. Social engagement and the risk of cardiovascular disease mortality: results of a prospective population-based study of older men. Annals of Epidemiology. 2008;18(6):479-483.

Ramsay SE, Whincup PH, Morris R, Lennon L, Wannamethee SG. Is socioeconomic position related to the prevalence of metabolic syndrome?: influence of social class across the life course in a population-based study of older men. Diabetes Care. 2008 Dec;31(12):2380-2.

Sattar N, McConnachie A, Shaper AG, Blauw GJ, Buckley BM, de Craen AJ, PhD, Ford I, Forouhi NG, Freeman DJ, Jukema JW, Lennon L , Macfarlane PW, Murphy MB, Packard CJ, Stott DJ, Westendorp RG, Whincup PH, Shepherd J, Wannamethee SG. Can metabolic syndrome usefully predict cardiovascular disease and diabetes? Outcome data from two prospective studies. The Lancet. 2008;371(9628): 1927-1935.

Sattar N, Wannamethee SG, Forouhi NG. Novel biochemical risk factors for type 2 diabetes: pathogenic insights or prediction possibilities? Diabetologia. 2008;51(6):926-40.

Sohaib SMA, Papacosta O, Morris RW, Macfarlane PW, Whincup PH. Length of the qt interval: determinants and prognostic implications in a population-based prospective study of older men Journal of Electrocardiology. 2008;41(6):704-710.

Wannamethee SG. 2007. Book chapter: Beer and adiposity. In VR. Preedy,ed. Beer in Health and disease prevention. . Elsevier Press .

Wannamethee SG. The metabolic syndrome and cardiovascular risk in the British Regional Heart Study. Int J Obes (Lond). 2008;32 (2):S25-9.

Wannamethee SG. Adiponectin and cardiovascular risk prediction:can the ambiguities be resolved? Nutr Metab Cardiovasc Dis. 2008;18(9):581-4.

Wannamethee SG, Lowe GDO, Rumley A, Lennon L, Whincup PH. Tissue Plasminogen Activator, von Willebrand Factor, and Risk of Type 2 Diabetes in Older Men. Diabetes Care 2008;31:995-1000.

Wannamethee SG, Lennon LT, Shaper AG. The value of gamma-glutamyltransferase in cardiovascular risk prediction in men without diagnosed cardiovascular disease or diabetes. Atherosclerosis 2008; 201(1): 168-175

Welsh P, Whincup PH, Papacosta O, Wannamethee SG, Lennon L, Thomson A, Rumley A, Lowe GD. Serum matrix metalloproteinase-9 and coronary heart disease: a prospective study in middle-aged men. QJM. 2008;101(10):785-791.

2007

Ramsay SE, Whincup PH, Morris RW, Lennon LT, Wannamethee SG. Are childhood socio-economic circumstances related to coronary heart disease risk in older men? Findings from a population-based study. International Journal of Epidemiology 2007;36(3):560-6.

Ramsay SE; Whincup PH; Wannamethee SG; Papacosta O; Lennon, LT; Thomas MC; Morris RW. Missed opportunities for secondary prevention of cerebrovascular disease in elderly British men from 1999 to 2005: a population based study. Journal of Public Health 2007;29(3):251-257.

Shaper AG. New baseline needed for alcohol and mortality studies. Addiction Research and Theory 2007;15 (1):26-29.

Wannamethee SG, Shaper AG, Lennon L, Whincup PH. Decreased muscle mass and increased central adiposity are independently related to mortality in older men. Am J Clin Nutr. 2007;86(5):1339-46.

Wannamethee SG, Whincup P, Rumley A, Lowe GD. Inter-relationships of interleukin-6, cardiovascular risk factors and the metabolic syndrome among older men. J Thromb Haemost 2007;5:1637-1643.

Wannamethee SG, Whincup P, Lennon L, Sattar N. Circulating adiponectin levels and mortality in elderly men with and without cardiovascular disease and heart failure. Arch Intern Med. 2007;167:1510-1517.

Wannamethee SG, Tchernova J, Whincup P, Lowe GD, Rumley A, Brown K, Cherry L, Sattar N. Associations of adiponectin with metabolic and vascular risk parameters in the British Regional Heart Study reveal stronger links to insulin resistance-related than to coronory heart disease risk-related parameters. International Journal of Obesity. 2007; 31:1089 - 1098.

Wannamethee SG, Lowe GD, Rumley A, Cherry L, Whincup P, Sattar N. Adipokines and risk of type 2 diabetes in older men.Diabetes Care. 2007;30(5): 1200-1205.

Panel Discussion I: Does Alcohol Consumption Prevent Cardiovascular Disease?
Annals of Epidemiology 2007;17 (5):S37-S39.

Panel Discussion V: The Message on Moderate Drinking. Annals of Epidemiology. 2007;17 (5):S110-S111.

Prospective Studies Collaboration. Blood cholesterol and vascular mortality by age, sex, and blood pressure: a meta-analysis of individual data from 61 prospective studies with 55 000 vascular deaths. Lancet 2007;37:1829-39. (BRHS collaborator)

2006

Patel R, Lawlor DA, Whincup P, Montaner D, Papacosta O, Brindle P, Ebrahim S. The detection, treatment and control of high blood pressure in older British adults: cross-sectional findings from the British Women's Heart and Health Study and the British Regional Heart Study. Journal of Human Hypertension. 2006;20(10):733-41.

Ramsay SE, Whincup PH, Lawlor DA, Papacosta O, Lennon LT, Thomas MC, Ebrahim S, Morris RW. Secondary prevention of coronary heart disease in older patients - changes since the introduction of the National Service Framework: a population based study. BMJ. 2006;332(7534):144-5.

Ramsay SE, Whincup PH, Shaper AG, Wannamethee SG. The relations of body composition and adiposity measures to ill health and physical disability in elderly men. American Journal of Epidemiology. 2006;164(5):459-69.

Rumley A, Emberson JR, Wannamethee SG, Lennon L, Whincup PH, Lowe GD. Effects of older age on fibrin D-dimer, C-reactive protein, and other hemostatic and inflammatory variables in men aged 60-79 years. J Thromb Haemost. 2006;4(5):982-7

Sattar N, Wannamethee G, Sarwar N, Tchernova J, Cherry L, Wallace AM, Danesh J, Whincup PH. Adiponectin and coronary heart disease: a prospective study and meta-analysis. Circulation 2006;114(7):623-9.

Wannamethee SG, Lowe GDO, Rumley A, Bruckdorfer KR, Whincup PH. Associations of vitamin C status, fruit and vegetable intake, and markers of inflammation and haemostasis. Am J Clin Nutr. 2006;83(3):567-74.

Wannamethee SG, Tchernova J, Whincup P, Lowe GD, Kelly A, Rumley A, Wallace AM, Sattar N. Plasma leptin: associations with metabolic, inflammatory and haemostatic risk factors for cardiovascular disease. Atherosclerosis. 2006 May 17; [Epub ahead of print]

Wannamethee SG. Exercise really is good for you. Heart. 2006;92(9):1185-6.

Wannamethee SG, Shaper AG Lowe GD, Lennon L, Rumley A, Whincup PH. Renal function and cardiovascular mortality in elderly men: the role of inflammatory, procoagulant and endothelial biomarkers. European Heart Journal. 2006 Nov 28; [Epub ahead of print]

Wannamethee SG, Shaper AG, Lennon L, Whincup PH. Height Loss in older men: associations with total mortality and incidence of cardiovasular disease. Arch Intern Med. 2006; 166(22):2546-52.

Whincup PH, Papacosta O, Lennon LT, Haines AH. Carboxyhaemoglobin levels and their determinants in older British men. BMC Public Health 2006;6(1):189.

2005

Emberson JR, Shaper AG, Wannamethee SG, Morris RW, Whincup PH. Alcohol intake in middle age and risk of cardiovascular disease and mortality: accounting for intake variation over time. Am J Epidemiol. 2005;161(9):856-863.

Emberson JR, Whincup PH, Lawlor DA, Montaner D, Ebrahim S. Coronary Heart Disease prevention in clinical practice - are patients with diabetes special? Evidence from the British Regional Heart Study and the British Women's Heart Health Study. Heart. 2005;91:451-455.

Emberson JR, Whincup PH, Morris RW, Wannamethee SG, Shaper AG. Lifestyle and cardiovascular disease in middle-aged British men: the effect of adjusting for within-person variation. EHJ. 2005;26:1774-1782.

Lampe FC, Morris RW, Walker M, Shaper AG, Whincup PH. Trends in rates of different forms of diagnosed coronary heart disease, 1978 to 2000: Prospective population-based study of British men. BMJ. 2005;330:1046-1050.

Lowe GD, Rumley A, Wannamethee SG. Hemostatic abnormalities associated with obesity and the metabolic syndrome. J Thromb Haemost. 2005;3(5):1076-8.

Mendis S, Abegunde D, Yusuf S, Ebrahim S , Shaper G , Ghannem H , Shengelia B. WHO study on Prevention of REcurrence of Myocardial Infarction and Stroke (WHO-PREMISE). Bulletin of the World |Health Organisation November 2005;83(11):820-828.

Morris RW, Whincup PH, Papacosta O, Walker M, Thomson A. Inequalities in coronary revascularisation during the 1990s - evidence from the British Regional Heart Study. Heart. 2005;91:635-640.

Morris RW, Emberson JR. Commentary: Over-correction for regression dilution bias? Not for blood pressure vs coronary heart disease. International Journal of Epidemiology. 2005;34:1368-1369.

Ramsay S E, Morris R W, Papacosta O, Lennon L T, Thomas M C, Whincup P H. Secondary prevention of coronary heart disease in older British men: extent of inequalities before and after implementation of the National Service Framework. JPH 2005;27 (4):338-343.

Thomas MC, Walker MK, Emberson JR, Thomson AG, Lawlor DA, Ebrahim S, Whincup PH. Prevalence of undiagnosed Type 2 diabetes and impaired fasting glucose in older British men and women. Diabetic Medicine.2005;22:789-793.

Wannamethee SG, Ebrahim S, Papacosta O, Shaper AG. From a postal questionnaire of older men, healthy lifestyle factors reduced the onset of and may increased recovery from mobility limitation. Journal of Clinical Epidemiology. 2005;58:831-840.

Wannamethee SG, Shaper AG, Morris R, Whincup PH. Measures of adiposity in the identification of metabolic abnormalities in elderly men. American Journal of Clinical Nutrition. 2005; 81: 1313-1321.

Wannamethee SG, Lowe GDO, Shaper AG, Rumley A, Lennon L, Whincup PH. The metabolic syndrome and insulin resistance and their relationship to haemostatic and inflammatory markers in older non-diabetic men. Atherosclerosis.2005;181:101-108.

Wannamethee SG, Shaper AG, Lennon L. Reasons for intentional weight loss, unintentional weight loss and mortality in older men. Archives of Internal Medicine.2005;165(9): 1035-1040.

Wannamethee SG, Shaper AG, Whincup PH, Walker M. Overweight and obesity and weight change in middle-aged men: impact on cardiovascular disease and diabetes. Journal of Epidemiology and Community Health. 2005;59(2):134-9.

Wannamethee SG, Lowe GDO, Shaper AG, Rumley A, Lennon L, Whincup PH. Associations between cigarette smoking, pipe/cigar smoking, and smoking cessation, and haemostatic and inflammatory markers for cardiovascular disease. EHJ. 2005; 26:1765-1773.

Wannamethee SG, Shaper AG, Whincup PH. Alcohol and adiposity: Effects of quantity and type of drink and time relation with meals. International Journal of Obesity. 2005 2005; 29:1436-1444.

Wannamethee SG, Shaper AG, Whincup PH. Body fat distribution, body composition and respiratory function in elderly men. American Journal of Clinical Nutrition. 2005;82(5):996-1003.

Wannamethee SG. Serum uric acid and risk of coronary heart disease. Current Pharmaceutical Design 2005; 11 (32):4125-4132.

Wannamethee SG. Commentary: Alcohol and mortality: diminishing returns for benefits of alcohol. International Journal of Epidemiology. 2005 Feb;34(1):205-6

Wannamethee SG, Shaper AG, Whincup PH, Lennon L. Hepatic enzymes, the metabolic syndrome and the risk of type 2 diabetes in older men. Diabetes Care 2005;28: 2913-2918

Wannamethee SG, Shaper AG, Lennon L, Morris RW. Metabolic Syndrome vs Framingham Risk Score for Prediction of Coronary Heart Disease, Stroke and Type 2 Diabetes Mellitus. Archives of Internal Medicine. 2005;165:2651-2658

Whincup PH, Emberson J, Morris R, Shaper A.G. Risk factors for coronary heart disease (letter). Lancet.2005;365:117.

Pre 2005 Publications

2004

Ebrahim S, Papacosta O, Wannamethee G, Adamson J. Social inequalities and disability in older men: prospective findings from the British Regional Heart Study. Social Science and Medicine. 2004;59:2109-2120.

Emberson JR, Whincup PH, Morris RW, Walker M, Ebrahim S. Evaluating the impact of population and high risk strategies for the primary prevention of cardiovascular disease. Eur.Heart J. 2004;25(6):484-491.

Emberson JR, Whincup PH, Morris RW, Walker M, Lowe GDO, Rumley A. Extent of regression dilution for established and novel coronary risk factors: results from the British Regional Heart Study. Eur J Cardio Prev Rehab 2004; 11: 125-134.

Emberson JR, Whincup PH, Morris RW, Walker M. Social class differences in coronary heart disease in middle-aged British men implications for prevention. Int J Epidemiol 2004; 33: 289-296.

Lawlor DA, Whincup PH, Sterne J, Papacosta O, Wannamethee G, Dhanjil S, Griffin M, Nicolaides AN, Davey Smith G. Sex differences in body fat distribution and carotid intima media thickness: cross sectional survey using data from the British Regional Heart Study. Journal of Epidemiology & Community Health. 2004;58:700-704.

Lawlor DA, Whincup PH, Emberson JR, Rees K, Walker M, Ebrahim S. The challenge of secondary prevention for coronary heart disease in older patients: findings from the British Women’s Heart and Health Study and the British Regional Heart Study. Family Practice. 2004;21:582-586.

Lowe GDO, Danesh J, Lewington S, Walker M, Lennon L, Thomson A, Rumley A, Whincup PH. Tissue plasminogen activator antigen and coronary heart disease: prospective study and meta-analysis. Eur. Heart J. 2004;25:252-259.

Shaper AG, Wannamethee SG, Whincup PH. Serum albumin and risk of stroke, CHD and mortality: the role of cigarette smoking. J Clinical Epidemiology. 2004;57(2):195-202.

Walker M, Whincup PH, Shaper AG. Cohort Profile: The British Regional Heart Study 1975-2004. IJE. 2004;33:1185-1192.

Wannamethee SG and Shaper AG. Alcohol, Overweight and Obesity. Published in: Nutrition and Alcohol. Linking Nutrient Interactions and Dietary Intake. Edited by Ronald R Ross and Victor R Preedy. CRC Press, Florida. 2004 pp365-76. ISBN 0-8493-1680-4.

Wannamethee SG, Lawlor DA, Whincup PH, Walker M, Ebrahim S, Davey-Smith G. Birthweight of offspring and paternal insulin resistance and paternal diabetes in late adult hood: cross sectional survey. Diabetologia 2004; 47:12-18.

Wannamethee SG, Shaper AG, Whincup PH, Walker M. Overweight obesity and burden of disease and disability in elderly men. International Journal of Obesity. 2004;28:1374-1382.

Wannamethee SG, Shaper AG, Lennon LT. Cardiovascular disease incidence and mortality in older men with diabetes and in men with coronary heart disease. Heart. 2004;90:1398-1403.

Wannamethee SG, Lowe GDO, Rumley A, Lennon L, Whincup PH. Insulin resistance, haemostatic and inflammatory markers and coronary heart disease risk factors in type 2 diabetes with and without CHD. Diabetologia. 2004;47:1557-1565.

Whincup PH, Gilg JA, Emberson JR, Jarvis MJ, Feyerabend C, Bryant A, Walker M, Cook DG. Passive smoking and risk of coronary heart disease and stroke: prospective study using cotinine measurement. BMJ. 2004;329:200-205.

2003

Brindle P, Emberson JR, Lampe FC, Walker M, Whincup PH, Fahey T, Ebrahim SB. Coronary risk-assessment: Framingham-based methods over-estimate risk in British middle-aged men. BMJ 2003; 327:1267-1272.

Conroy RM, Pyorala K, Fitzgerald AP, Sans S, Menotti A, De Backer G et al. Estimation of ten-year risk of fatal cardiovascular disease in Europe: the SCORE project. European Heart Journal 2003; 24(11):987-1003.

Danesh J, Whincup P, Walker M. Chlamydia pneumoniae IgA titres and coronary heart disease: prospective study and meta-analysis (letter). European Heart Journal 2003; 24(9):881.

Emberson JR, Whincup PH, Morris RW, Walker M. Re-assessing the contribution of serum total cholesterol, blood pressure and cigarette smoking to the aetiology of coronary heart disease: impact of regression dilution bias. European Heart Journal 2003; 24(19):1719-1726.

Lawlor DA,Emberson JR, Ebrahim SE, Whincup PH, Wannamethee SG, Walker M, Davey-Smith G. Is the association between parity and coronary heart disease due to biological effects of pregnancy or adverse lifestyle risk factors associated with childrearing? Findings from the British Women's Heart and Health Study and the British Regional Heart Study. Circulation 2003;107:1254-58.

Lawlor DA, Davey Smith G, Whincup P, Wannamethee G, Papacosta O, Dhanjil S, Griffin M, Nicolaides AN, Ebrahim S. Association between offspring birth weight and atherosclerosis in middle aged men and women: British Regional Heart Study. J Epidemiol Community Health. 2003 Jun;57(6):462-3.

Morris RW, Whincup PH, Emberson JR, Lampe FC, Walker M, Shaper AG. North-South Gradients in Britain for Stroke and CHD. Are They Explained by the Same Factors? Stroke 2003;34:2604-2609.

Shaper A.G., Wannamethee S.G., Walker M. Pipe and cigar smoking and major cardiovascular events, cancer incidence and all-cause mortality in middle-aged British men. International Journal of Epidemiology 2003;32:802-808.

Wannamethee SG, Shaper AG. Alcohol, bodyweight and weight gain in middle-aged men. Am. J Clin Nutr 2003;77:1312-1

Wannamethee SG, Lowe GDO, Shaper AG, Whincup PH, Rumley A, Walker M, Lennon L. The effects of different alcoholic drinks on lipids, insulin and haemostatic and inflammatory markers in older men. Thrombosis and Haemostasis 2003;90:1080-7.

2002

Danesh J, Whincup P, Lewington S, Walker M, Lennon L, Thomson A et al. Chlamydia pneumoniae IgA titres and coronary heart disease; prospective study and meta-analysis. Eur Heart J 2002; 23(5):371-375.

Emberson JR, Whincup PH, Walker M, Thomas M, Alberti KG. Biochemical measures in a population-based study: effect of fasting duration and time of day. Annals of Clinical Biochemistry 2002;39(5):493-501.

Lennon L.T. Can the world wide web be used to improve health knowledge management in the British Regional Heart Study? Thesis: MSc. 2002 University of London.

Thomas MC, Walker M, Lennon LT, Thomson AG, Lampe FC, Shaper AG. Non-attendance at re-examination 20 years after screening in the British Regional Heart Study. Journal of Public Health Medicine 2002;24:285-291.

Wannamethee SG, Shaper AG. Physical activity and risk of coronary heart disease (review). Seminars in Vascular Medicine 2002;2(3): 257-265.

Wannamethee SG, Shaper AG. Taking up regular drinking in middle age: effect on major coronary heart disease events and mortality. Heart 2002;87(1):32-36.

Wannamethee SG, Shaper AG. Wine and lifestyle: role in CVD and premature death. In Alcohol and Heart Disease. Edited byWatson RR, Myers AK. Published by Taylor & Francis London. 2002 Chapter 3 p21-27.

Wannamethee SG, Lowe GD, Whincup PH, Rumley A, Walker M, Lennon L. Physical activity and hemostatic and inflammatory variables in elderly men. Circulation 2002;105(15):1785-1790.

Wannamethee SG, Shaper AG, Perry IJ, Alberti K-GMM. Alcohol consumption and the incidence of type II diabetes. J Epidemiol Community Health 2002;56(7):542-548.

Wannamethee SG, Shaper AG, Whincup PH, Walker M. Migration within Great Britain and cardiovascular disease: early life and adult environmental factors. International Journal of Epidemiology 2002;31:1054-1060.

Wannamethee SG, Shaper AG, Walker M. Weight Change, Weight Fluctuation, and Mortality.Archives of Internal Medicine. 2002;162:2575-2580.

Whincup PH, Danesh J, Walker M, Lennon L, Thomson A, Appleby P et al. von Willebrand factor and coronary heart disease. Prospective study and meta-analysis. Eur.Heart J. 2002;23:1764-1770.

Whincup PH, Emberson JR, Lennon L, Walker M, Papacosta O, Thomson A. Low prevalence of lipid lowering drug use in older men with established coronary heart disease. Heart 2002; 88(1):25-29.

Homocysteine Studies Collaboration. (Whincup PH). Homocysteine and risk of ischaemic heart disease and stroke: 6000 events in 30 observational studies. JAMA 2002;288:2015-22 .

Prospective Studies Collaboration (BRHS: PH Whincup et al). Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies. Lancet 2002;360:1903-13.

2001

Danesh J, Whincup P, Walker M, Lennon L, Thomson A, Appleby P et al. Fibrin D-dimer and coronary heart disease: prospective study and meta-analysis. Circulation 2001; 103(19):2323-2327. Dekou V, Whincup P, Papacosta O, Ebrahim S, Lennon L, Ueland PM et al. The effect of the C677T and A1298C polymorphisms in the methylenetetrahydrofolate reductase gene on homocysteine levels in elderly men and women from the British regional heart study. Atherosclerosis 2001; 154(3):659-666.

Ebrahim S, Shlomo YB, Smith GD, Whincup P, Emberson J. Dementia and statins (letter). Lancet 2001; 357(9259):822.

Lampe FC, Whincup PH, Shaper AG, Wannamethee SG, Walker M, Ebrahim S. Variability of angina symptoms and the risk of major ischemic heart disease events. American Journal of Epidemiology 2001; 153(12):1173-1182.

Lampe FC, Walker M, Shaper AG, Brindle PM, Whincup PH, Ebrahim S. End points for predicting coronary risk must be clarified (letter). British Medical Journal 2001; 323(7309):396-397.

Lampe FC, Morris RW, Whincup PH, Walker M, Ebrahim S, Shaper AG. Is the prevalence of coronary heart disease falling in British men? Heart 2001; 86(5):449-505.

Malik I, Danesh J, Whincup P, Bhatia V, Papacosta O, Walker M et al. Soluble adhesion molecules and prediction of coronary heart disease: a prospective study and meta-analysis. Lancet 2001; 358(9286):971-976.

Morris RW, Whincup PH, Lampe FC, Walker M, Wannamethee SG, Shaper AG. Geographic variation in incidence of coronary heart disease in Britain: the contribution of established risk factors. Heart 2001; 86(3):277-283.

Vass A, Leng G, Papacosta O, Walker M, Lennon L, Whincup PH. Secondary prevention may help intermittent claudication (letter). British Medical Journal 2001; 322(7287):673.

Walker M, Thomson A, Whincup PH. Screening for type 2 diabetes. Screening would have important resource implications for primary care (letter). British Medical Journal 2001; 323(7310):454-455.

Wannamethee SG, Shaper AG. Physical activity in the prevention of cardiovascular disease: an epidemiological perspective. [Review]. Sports Medicine 2001; 31(2):101-114.

Wannamethee SG, Shaper AG, Perry IJ. Smoking as a modifiable risk factor for type 2 diabetes in middle-aged men. Diabetes Care 2001; 24(9):1590-1595.

Wannamethee SG, Shaper AG, Walker M. Weight change, body weight and mortality: the impact of smoking and ill health. International Journal of Epidemiology 2001; 30(4):777-786.

Wannamethee SG. Serum uric acid is not an independent risk factor for coronary heart disease. [Review]. Current Hypertension Rep 2001; 3(3):190-196.

Wannamethee SG, Shaper AG, Walker M. Physical activity and risk of cancer in middle-aged men. British Journal of Cancer 2001; 85(9):1311-1316.

2000

Danesh J, Whincup P, Walker M, Lennon L, Thomson A, Appleby P et al. Chlamydia pneumoniae IgG titres and coronary heart disease: prospective study and meta-analysis. British Medical Journal 2000; 321(7255):208-213. Danesh J, Whincup P, Walker M, Lennon L, Thomson A, Appleby P et al. Low grade inflammation and coronary heart disease: prospective study and updated meta-analyses. British Medical Journal 2000; 321(7255):199-204.

Danesh J, Whincup P, Walker M, Lennon L, Thomson A, Appleby P et al. High prevalence of potentially virulent strains of Helicobacter pylori in the general male British population. Gut 2000; 47(1):23-25.

Ebrahim S, Wannamethee SG, Whincup P, Walker M, Shaper AG. Locomotor disability in a cohort of British men: the impact of lifestyle and disease. International Journal of Epidemiology 2000; 29(3):478-486.

Lampe FC, Whincup PH, Wannamethee SG, Shaper AG, Walker M, Ebrahim S. The natural history of prevalent ischaemic heart disease in middle-aged men. European Heart Journal 2000; 21(13):1052-1062.

Leng GC, Papacosta O, Whincup P, Wannamethee G, Walker M, Ebrahim S et al. Femoral atherosclerosis in an older British population: prevalence and risk factors. Atherosclerosis 2000; 152(1):167-174.

Shaper AG, Wannamethee SG. Epidemiological confounders in the relationship between alcohol and cardiovascular disease. In Moderate alcohol consumption and cardiovascular disease. Editors: Paoletti R, Klatsky AL, Poli A, Zakhari S. Publishers: Kluwer Academic Publishers, Dordrecht. 2000 105-112.

Shaper AG, Wannamethee SG. Alcohol intake and mortality in middle aged men with diagnosed coronary heart disease. Heart 2000; 83(4):394-399.

Walker M, Shaper AG, Lennon L, Whincup PH. Twenty year follow-up of a cohort based in general practice in 24 British towns. Journal of Public Health Medicine 2000; 22(4):479-485.

Wannamethee SG, Shaper AG, Alberti KGMM. Physical activity, metabolic factors, and the incidence of coronary heart disease and type 2 diabetes. Archives of Internal Medicine 2000; 160(14):2108-2116.

Wannamethee SG, Shaper AG, Walker M. Physical activity and mortality in older men with diagnosed coronary heart disease. Circulation 2000; 102(12):1358-1363.

Wannamethee SG, Shaper AG. HDL-cholesterol, total cholesterol and the risk of stroke in middle-aged British men. Stroke 2000; 31(8):1882-1888.

Wannamethee SG, Shaper AG, Whincup PH, Walker M. Characteristics of older men who lose weight intentionally or unintentionally. American Journal of Epidemiology 2000; 151(7):667-675.

Whincup P, Danesh J, Walker M, Lennon L, Thomson A, Appleby P et al. Prospective study of potentially virulent strains of Helicobacter pylori and coronary heart disease in middle-aged men. Circulation 2000; 101(14):1647-1652.

1999

Cook DG, Whincup PH, Miller G, Carey IM, Adshead FJ, Papacosta O et al. Fibrinogen and factor VII levels are related to adiposity but not to fetal growth or social class in children aged 10-11 years. American Journal of Epidemiology 1999; 150(7):727-736.

Ebrahim S, Papacosta O, Whincup P, Wannamethee G, Walker M, Nicolaides AN et al. Carotid plaque, intima media thickness, cardiovascular risk factors, and prevalent cardiovascular disease in men and women: the British Regional Heart Study. Stroke 1999; 30(4):841-850.

Lampe FC, Walker M, Lennon LT, Whincup PH, Ebrahim S. Validity of a self-reported history of doctor-diagnosed angina. Journal of Clinical Epidemiology 1999; 52(1):73-81.

Perry IJ, Wannamethee SG, Shaper AG, Alberti KG. Serum true insulin concentration and the risk of clinical non-insulin dependent diabetes during long-term follow-up. International Journal of Epidemiology 1999; 28(4):735-741.

Perry IJ. Homocysteine and risk of stroke. Journal of Cardiovascular Risk 1999; 6(4):235-240.

Shaper AG. Drinking after a heart attack (Editorial). Addiction 1999; 94(7):957-959.

Walker M, Shaper AG, Wannamethee SG, Whincup PH. Measuring the prevalence of disease in middle-aged British men. Journal of the Royal College of Physicians of London 1999; 33(4):351-358.

Wannamethee SG, Perry IJ, Shaper AG. Nonfasting serum glucose and insulin concentrations and the risk of stroke. Stroke 1999; 30(9):1780-1786.

Wannamethee SG, Shaper AG. Weight change and duration of overweight and obesity in the incidence of type 2 diabetes. Diabetes Care 1999; 22(8):1266-1272.

Wannamethee SG, Shaper AG. Physical activity and the prevention of stroke. Journal of Cardiovascular Risk 1999; 6(4):213-216.

Wannamethee SG, Shaper AG. Type of alcoholic drink and risk of major coronary heart disease events and all-cause mortality. American Journal of Public Health 1999; 89(5):685-690.

Wannamethee SG. Overview risk factors for stroke. Journal of Cardiovascular Risk 1999; 6(4):199-202.

Wannamethee SG. Is serum uric acid a risk factor for coronary heart disease?. [Review]. Journal of Human Hypertension 1999; 13(3):153-156.

Wannamethee SG, Shaper AG, Whincup PH, Walker M. Role of risk factors for major coronary heart disease events with increasing length of follow up. Heart 1999; 81(4):374-379.

Whincup PH, Refsum H, Perry IJ, Morris R, Walker M, Lennon L et al. Serum total homocysteine and coronary heart disease: prospective study in middle aged men. Heart 1999; 82(4):448-454.

1998

Lampe FC, Whincup PH, Wannamethee SG, Ebrahim S, Walker M, Shaper AG. Chest pain on questionnaire and prediction of major ischaemic heart disease events in men. European Heart Journal 1998; 19(1):63-73.

Perry IJ, Wannamethee SG, Shaper AG. Prospective study of serum gamma-glutamyltransferase and risk of NIDDM. Diabetes Care 1998; 21(5):732-737.

Shaper AG, Wannamethee SG. The J-shaped curve and changes in drinking habit. [Review]. Novartis Foundation Symposium 216. 1998;173-188.

Taylor SJ, Hird K, Whincup P, Cook D. Relation between birth weight and blood pressure is independent of maternal blood pressure [letter]. British Medical Journal 1998; 317(7159):680.

Walker MK, Whincup PH, Shaper AG, Lennon LT, Thomson AG. Validation of patient recall of doctor-diagnosed heart attack and stroke: a postal questionnaire and record review comparison. American Journal of Epidemiology 1998; 148(4):355-361.

Wannamethee SG, Shaper AG, Walker M, Ebrahim S. Lifestyle and 15-year survival free of heart attack, stroke, and diabetes in middle-aged British men. Archives of Internal Medicine 1998; 158(22):2433-2440.

Wannamethee SG, Shaper AG, Durrington PN, Perry IJ. Hypertension, serum insulin, obesity and the metabolic syndrome. Journal of Human Hypertension 1998; 12(11):735-741.

Wannamethee SG, Shaper AG, Whincup PH, Walker M. Adult height, stroke, and coronary heart disease. American Journal of Epidemiology 1998; 148(11):1069-1076.

Wannamethee SG, Shaper AG. Alcohol, coronary heart disease and stroke: an examination of the J-shaped curve. [Review]. Neuroepidemiology 1998; 17(6):288-295.

Wannamethee SG, Shaper AG, Walker M. Changes in physical activity, mortality, and incidence of coronary heart disease in older men. Lancet 1998; 351(9116):1603-1608.

Whincup PH. Fetal origins of cardiovascular risk: evidence from studies in children. [Review]. Proceedings of the Nutrition Society 1998; 57(1):123-127.

1997

Cook DG, Carey IM, Whincup PH, Papacosta O, Chirico S, Bruckdorfer KR et al. Effect of fresh fruit consumption on lung function and wheeze in children. Thorax 1997; 52(7):628-633. Leeson CP, Whincup PH, Cook DG, Donald AE, Papacosta O, Lucas A et al. Flow-mediated dilation in 9- to 11-year-old children: the influence of intrauterine and childhood factors. Circulation 1997; 96(7):2233-2238.

McCallum AK, Whincup PH, Morris RW, Thomson A, Walker M, Ebrahim S. Aspirin use in middle-aged men with cardiovascular disease: are opportunities being missed? British Journal of General Practice 1997; 47(420):417-421.

Perry IJ, Wannamethee SG, Shaper AG. Serum insulin and risk of coronary heart disease. Nutrition Metabolism and Cardiovascular Diseases 1997; 7:63-69.

Shaper AG, Wannamethee SG, Walker M. Body weight: implications for the prevention of coronary heart disease, stroke, and diabetes mellitus in a cohort study of middle aged men. British Medical Journal 1997; 314(7090):1311-1317.

Taylor SJ, Whincup PH, Cook DG, Papacosta O. Blood pressure in pregnancy and fetal growth [letter]. Lancet 1997; 349(9054):802-803.

Taylor SJ, Whincup PH, Cook DG, Papacosta O, Walker M. Size at birth and blood pressure: cross sectional study in 8-11 year old children. British Medical Journal 1997; 314(7079):475-480.

Wannamethee SG, Shaper AG. Lifelong teetotallers, ex-drinkers and drinkers: mortality and the incidence of major coronary heart disease events in middle-aged British men. International Journal of Epidemiology 1997; 26(3):523-531.

Wannamethee SG, Shaper AG, Whincup PH. Serum urate and the risk of major coronary heart disease events. Heart 1997; 78(2):147-153.

Wannamethee SG, Shaper AG. Socioeconomic status within social class and mortality: a prospective study in middle-aged British men. International Journal of Epidemiology 1997; 26(3):532-541.

Wannamethee SG, Shaper AG, Perry IJ. Serum creatinine concentration and risk of cardiovascular disease: a possible marker for increased risk of stroke. Stroke 1997; 28(3):557-563.

Wannamethee SG, Lever AF, Shaper AG, Whincup PH. Serum potassium, cigarette smoking, and mortality in middle-aged men. American Journal of Epidemiology 1997; 145(7):598-606.

Whincup PH, Cook DG, Adshead F, Taylor SJ, Walker M, Papacosta O et al. Childhood size is more strongly related than size at birth to glucose and insulin levels in 10-11-year-old children. Diabetologia 1997; 40(3):319-326.

1996

Griffin M. High resolution ultrasound increasing the predictive value of the British Regional Heart Study risk score. Thesis: MSc. 1996 University of London. Morris RW, McCallum AK, Walker M, Whincup PH, Ebrahim S, Shaper AG. Cigarette smoking in British men and selection for coronary artery bypass surgery. Heart 1996; 75(6):557-562.

Perry IJ. Risk factors for non-insulin dependent diabetes mellitus in middle-aged men. Thesis: PhD. 1996 University of London.

Perry IJ, Wannamethee SG, Whincup PH, Shaper AG, Walker MK, Alberti KG. Serum insulin and incident coronary heart disease in middle-aged British men. American Journal of Epidemiology 1996; 144(3):224-234.

Phillips AN, Wannamethee SG, Walker M, Thomson A, Smith GD. Life expectancy in men who have never smoked and those who have smoked continuously: 15 year follow up of large cohort of middle aged British men. British Medical Journal 1996; 313(7062):907-908.

Shaper AG. Obesity and cardiovascular disease. [Review]. Ciba Foundation Symposium 201 1996;90-103.

Shaper AG. Sensible but not particularly logical. (Commentary on Guidelines on sensible drinking). Addiction 1996; 91(1):29-31.

Wannamethee G, Shaper AG. Blood pressure and cancer in middle-aged British men. International Journal of Epidemiology 1996; 25(1):22-31.

Wannamethee SG, Perry IJ, Shaper AG. Hematocrit and risk of NIDDM. Diabetes 1996; 45(5):576-579.

Wannamethee SG, Shaper AG. Patterns of alcohol intake and risk of stroke in middle-aged British men. Stroke 1996; 27(6):1033-1039.

Wannamethee SG, Whincup PH, Shaper G, Walker M. Influence of fathers' social class on cardiovascular disease in middle-aged men. Lancet 1996; 348(9037):1259-1263.

Wannamethee SG, Shaper AG, Ebrahim S. History of parental death from stroke or heart trouble and the risk of stroke in middle-aged men. Stroke 1996; 27(9):1492-1498.

Whincup PH, Mendall MA, Perry IJ, Strachan DP, Walker M. Prospective relations between Helicobacter pylori infection, coronary heart disease, and stroke in middle aged men. Heart 1996; 75(6):568-572.

Whincup PH, Cook DG, Adshead F, Taylor S, Papacosta O, Walker M et al. Cardiovascular risk factors in British children from towns with widely differing adult cardiovascular mortality. British Medical Journal 1996; 313(7049):79-84.

1995

Breimer LH, Wannamethee G, Ebrahim S, Shaper AG. Serum bilirubin and risk of ischemic heart disease in middle-aged British men. Clinical Chemistry 1995; 41(10):1504-1508. Coppola WG, Whincup PH, Papacosta O, Walker M, Ebrahim S. Scoring system to identify men at high risk of stroke: a strategy for general practice. British Journal of General Practice 1995; 45(393):185-189.

Ebrahim S, Wannamethee G, McCallum A, Walker M, Shaper AG. Marital status, change in marital status, and mortality in middle-aged British men. American Journal of Epidemiology 1995; 142(8):834-842.

Perry IJ, Wannamethee SG, Walker MK, Thomson AG, Whincup PH, Shaper AG. Prospective study of risk factors for development of non-insulin dependent diabetes in middle aged British men. British Medical Journal 1995; 310(6979):560-564.

Perry IJ, Refsum H, Morris RW, Ebrahim SB, Ueland PM, Shaper AG. Prospective study of serum total homocysteine concentration and risk of stroke in middle-aged British men. Lancet 1995; 346(8987):1395-1398.

Prospective Studies Collaboration. Cholesterol, diastolic blood pressure, and stroke: 13,000 strokes in 450,000 people in 45 prospective cohorts. Lancet 1995; 346(8991-8992):1647-1653.

Shaper AG. Alcohol and coronary heart disease. [Review]. European Heart Journal 1995; 16(12):1760-1764.

Shaper AG. Alcohol and uricaemia [letter]. Alcohol & Alcoholism 1995; 30(2):263.

Shaper AG. Mortality and alcohol consumption. Non-drinkers shouldn't be used as baseline [letter]. British Medical Journal 1995; 310(6975):325.

Shaper AG. The "unhealthy abstainers" question is still important. Addiction 1995; 90(4):488-490.

Walker M, Wannamethee G, Whincup PH, Shaper AG. Weight change and risk of heart attack in middle-aged British men. International Journal of Epidemiology 1995; 24(4):694-703.

Wannamethee G, Shaper AG, Whincup PH, Walker M. Low serum total cholesterol concentrations and mortality in middle aged British men. British Medical Journal 1995; 311(7002):409-413.

Wannamethee G, Shaper AG, Macfarlane PW, Walker M. Risk factors for sudden cardiac death in middle-aged British men. Circulation 1995; 91(6):1749-1756.

Wannamethee G, Whincup PH, Shaper AG, Walker M, Macfarlane PW. Factors determining case fatality in myocardial infarction "who dies in a heart attack"? British Heart Journal 1995; 74(3):324-331.

Wannamethee G, Ebrahim S, Shaper AG. Gamma-glutamyltransferase: determinants and association with mortality from ischemic heart disease and all causes. American Journal of Epidemiology 1995; 142(7):699-708.

Wannamethee SG, Shaper AG, Ebrahim S. Respiratory function and risk of stroke. Stroke 1995; 26(11):2004-2010.

Wannamethee SG, Shaper AG, Whincup PH, Walker M. Smoking cessation and the risk of stroke in middle-aged men. JAMA 1995; 274(2):155-160.

Whincup P, Cook D, Papacosta O, Walker M. Birth weight and blood pressure: cross sectional and longitudinal relations in childhood. British Medical Journal 1995; 311(7008):773-776.

Whincup PH, Wannamethee G, Macfarlane PW, Walker M, Shaper AG. Resting electrocardiogram and risk of coronary heart disease in middle-aged British men. Journal of Cardiovascular Risk 1995; 2(6):533-543.

1994

Cook DG, Whincup PH, Jarvis MJ, Strachan DP, Papacosta O, Bryant A. Passive exposure to tobacco smoke in children aged 5-7 years: individual, family, and community factors. British Medical Journal 1994; 308(6925):384-389. Geroulakos G, O'Gorman D, Nicolaides A, Sheridan D, Elkeles R, Shaper AG. Carotid intima-media thickness: correlation with the British Regional Heart Study risk score. Journal of Internal Medicine 1994; 235(5):431-433.

Morris JK, Cook DG, Shaper AG. Loss of employment and mortality. British Medical Journal 1994; 308(6937):1135-1139.

Morris RW, Walker M, McCallum AK, Whincup PH, Ebrahim S. Access to cardiac catheterization. Access to surgery linked to social class (letter). British Medical Journal 1994; 308(6925):410.

Perry IJ, Whincup PH, Shaper AG. Environmental factors in the development of essential hypertension. [Review]. British Medical Bulletin 1994; 50(2):246-259.

Perry IJ, Wannamethee SG, Whincup PH, Shaper AG. Asymptomatic hyperglycaemia and major ischaemic heart disease events in Britain. Journal of Epidemiology & Community Health 1994; 48(6):538-542.

Shaper AG, Perry IJ. Screening people with diabetes for risk of coronary heart disease in general practice. Practical Diabetes 1994; 11:228-231.

Shaper AG, Wannamethee G, Walker M. Physical activity, hypertension and risk of heart attack in men without evidence of ischaemic heart disease. Journal of Human Hypertension 1994; 8(1):3-10.

Shaper AG, Wannamethee SG. Physical activity and cerebrovascular risk. In Neurocardiology Update: Proceedings of the III National Congress Italian Society of Cardiology. Editors: Nappi G, Richichi I, Michieli G, Friedman M. Publishers: Smith-Gordon London 1994;(2) 7-12.

Shaper AG, Wannamethee G, Walker M. Alcohol and coronary heart disease: a perspective from the British Regional Heart Study. International Journal of Epidemiology 1994; 23(3):482-494.

Shaper AG. Water hardness and coronary heart disease. In Water and Public Health. Editors: Golding, AMB., Noah N, Stanwell-Smith R. Publishers: Smith-Gordon London 1994;155-170.

Wannamethee G, Whincup PH, Shaper AG, Lever AF. Serum sodium concentration and risk of stroke in middle-aged males. Journal of Hypertension 1994; 12(8):971-979.

Wannamethee G, Shaper AG. The association between heart rate and blood pressure, blood lipids and other cardiovascular risk factors. Journal of Cardiovascular Risk 1994; 1(3):223-230.

Wannamethee G, Perry IJ, Shaper AG. Haematocrit, hypertension and risk of stroke. Journal of Internal Medicine 1994; 235(2):163-168.

Wannamethee G, Shaper AG. Haematocrit: relationships with blood lipids, blood pressure and other cardiovascular risk factors. Thrombosis & Haemostasis 1994; 72(1):58-64.

Wannamethee G, Shaper AG, Whincup PH. Ischaemic heart disease: association with haematocrit in the British Regional Heart Study. Journal of Epidemiology & Community Health 1994; 48(2):112-118.

Whincup P, Cook D, Papacosta O, Walker M, Perry I. Maternal factors and development of cardiovascular risk: evidence from a study of blood pressure in children. Journal of Human Hypertension 1994; 8(5):337-343.

Whincup PH, Perry IJ, Shaper AG. Regional differences in blood pressure in developed countries: Fetal influences. In Factors acting in early life. Editor: Swales JD. Publishers: Blackwell Scientific London, 1994; Chapter 2: 36-45.

1993

Bruce NG, Wannamethee G, Shaper AG. Lifestyle factors associated with geographic blood pressure variations among men and women in the UK. Journal of Human Hypertension 1993; 7(3):229-238. Cook DG, Whincup PH, Papacosta O, Strachan DP, Jarvis MJ, Bryant A. Relation of passive smoking as assessed by salivary cotinine concentration and questionnaire to spirometric indices in children. Thorax 1993; 48(1):14-20.

Perry IJ, Wannamethee SG, Walker MK, Shaper AG. Sporting activity and hyperglycemia in middle-aged men. Diabetes Care 1993; 16(4):581-583.

Shaper AG, Wannamethee G, Macfarlane PW, Walker M. Heart rate, ischaemic heart disease, and sudden cardiac death in middle-aged British men. British Heart Journal 1993; 70(1):49-55.

Shaper AG. Alcohol, the Heart, and Health [editorial]. American Journal of Public Health 1993; 83(6):799-801.

Shaper AG. Alcohol and Coronary Heart Disease. Cardiovascular Risk Factors 1993; 3(4):207-214.

Wannamethee G, Shaper AG, Macfarlane PW. Heart rate, physical activity, and mortality from cancer and other non-cardiovascular diseases. American Journal of Epidemiology 1993; 137(7):735-748.

Whincup PH, Papacosta O, Cook DG. Initiation of hypertension in utero [letter]. British Medical Journal 1993; 306(6877):584.

Whincup PH, Cook DG, Strachan DP, Papacosta O. Time trends in respiratory symptoms in childhood over a 24 year period. Archives of Disease in Childhood 1993; 68(6):729-734.

1992

Bruce NG, Cook DG, Shaper AG, Ratcliffe JG, Thomson AG. Casual urine concentrations of sodium and potassium and geographic blood pressure variations in Great Britain. Journal of Human Hypertension 1992; 6(2):157-164. Elford J, Shaper AG, Whincup P. Early life experience and cardiovascular disease--ecological studies. [Review]. Journal of Epidemiology & Community Health 1992; 46(1):1-8.

Morris J. Loss of employment and ill health. Thesis: PhD. 1992 University of London.

Morris JK, Cook DG, Shaper AG. Non-employment and changes in smoking, drinking, and body weight. British Medical Journal 1992; 304(6826):536-541.

Morris JK, Cook DG, Walker M, Shaper AG. Non-consulters and high consulters in general practice: cardio-respiratory health and risk factors. Journal of Public Health Medicine 1992; 14(2):131-137.

Phillips AN, Neaton JD, Cook DG, Grimm RH, Shaper AG. Leukocyte count and risk of major coronary heart disease events. American Journal of Epidemiology 1992; 136(1):59-70.

Phillips AN, Neaton JD, Cook DG, Grimm RH, Shaper AG. The leukocyte count and risk of lung cancer. Cancer 1992; 69(3):680-684.

Shaper AG, Elford J. Regional variations in coronary heart disease in Great Britain: risk factors and changes in environment. In Coronary Heart Disease Epidemiology. From Aetiology to Public Health. Editors: Marmot M, Elliott P. Publishers: Oxford University Press Oxford 1992;(9):129-141.

Shaper AG. Stroke [letter]. Lancet 1992;339 (8795):750.

Tang JL, Cook DG, Shaper AG. Giving up smoking: How rapidly does the excess risk of ischaemic heart disease disappear? Journal of Smoking-Related Diseases 1992; 3(3):203-215.

Wannamethee SG. Alcohol, cardiovascular disease and all cause mortality in British middle-aged men. Thesis: PhD. 1992 University of London.

Wannamethee G, Shaper AG. Physical activity and stroke in British middle aged men. British Medical Journal 1992; 304(6827):597-601.

Wannamethee G, Shaper AG. Alcohol and sudden cardiac death. British Heart Journal 1992; 68(5):443-448.

Wannamethee G, Shaper AG. Blood lipids: the relationship with alcohol intake, smoking, and body weight. Journal of Epidemiology & Community Health 1992; 46(3):197-202.

Whincup PH, Cook DG, Papacosta O, Walker M. Childhood blood pressure, body build, and birthweight: geographical associations with cardiovascular mortality. Journal of Epidemiology & Community Health 1992; 46(4):396-402.

Whincup PH, Cook DG, Papacosta O. Do maternal and intrauterine factors influence blood pressure in childhood? Archives of Disease in Childhood 1992; 67(12):1423-1429.

Whincup PH, Bruce NG, Cook DG, Shaper AG. The Dinamap 1846SX automated blood pressure recorder: comparison with the Hawksley random zero sphygmomanometer under field conditions. Journal of Epidemiology & Community Health 1992; 46(2):164-169.

1991

Bruce NG. An investigation of geographic blood pressure variations among men and women in Great Britain. Thesis: PhD. 1991 University of London. Bruce N, Elford J, Wannamethee G, Shaper AG. The contribution of environmental temperature and humidity to geographic variations in blood pressure. Journal of Hypertension 1991; 9(9):851-858.

Elford J, Whincup P, Shaper AG. Early life experience and adult cardiovascular disease: longitudinal and case-control studies. [Review]. International Journal of Epidemiology 1991; 20(4):833-844.

Phillips AN, Smith GD. How independent are "independent" effects? Relative risk estimation when correlated exposures are measured imprecisely. Journal of Clinical Epidemiology 1991; 44(11):1223-1231.

Phillips AN, Shaper AG. Serum calcium and blood pressure. Journal of Human Hypertension 1991; 5(6):479-484.

Shaper AG, Wannamethee G, Walker M. Milk, butter, and heart disease [letter]. British Medical Journal 1991; 302(6779):785-786.

Shaper AG, Wannamethee G, Walker M. Calf pain on walking, risk factors and cardiovascular outcome in middle-aged British men. In Epidemiology of Peripheral Vascular Disease. Editor: Fowkes F. G. R. Publishers: Springer Verlag, London 1991;(11) 127-135.

Shaper AG. Screening for men at high-risk of coronary heart disease. Journal of the Society of Occupational Medicine 1991;41(2): 65-67.

Shaper AG, Wannamethee G, Weatherall R. Physical activity and ischaemic heart disease in middle-aged British men. British Heart Journal 1991; 66(5):384-394. (published erratum appears in Br Heart J 1992;67(2):209).

Shaper AG, Elford J. Place of birth and adult cardiovascular disease: the British Regional Heart Study. Acta Paediatrica Scandinavica - Supplement 1991; 373:73-81.

Shaper AG, Phillips AN, Pocock SJ, Walker M, Macfarlane PW. Risk factors for stroke in middle aged British men. British Medical Journal 1991; 302(6785):1111-1115.

Shaper AG, Walker M. Estimating the risk of heart attack (letter). British Medical Journal 1991; 303(6813): 1333-1334.

Tang JL. Giving up smoking and the risk of ischaemic heart disease. Thesis: PhD. 1991 University of London.

Wannamethee G, Shaper AG. Self-assessment of health status and mortality in middle-aged British men. International Journal of Epidemiology 1991; 20(1):239-245.

Wannamethee G, Shaper AG. Alcohol intake and variations in blood pressure by day of examination. Journal of Human Hypertension 1991; 5(2):59-67.

Whincup PH. A study of blood pressure in children in nine British towns. Thesis: PhD. 1991 University of London.

1990

Bruce NG, Cook DG, Shaper AG, Thomson AG. Geographical variations in blood pressure in British men and women. Journal of Clinical Epidemiology 1990; 43(4):385-398.

Bruce NG, Cook DG, Shaper AG. Differences between observers in blood pressure measurement with an automatic oscillometric recorder. Journal of Hypertension 1990; 8(4):S11-S13.

Bruce NG, Cook DG, Shaper AG, Ratcliffe JG. Casual urine concentrations of sodium, potassium, and creatinine in population studies of blood pressure. Journal of Human Hypertension 1990; 4(6):597-602.

Cook DG, Morris JK, Walker M, Shaper AG. Consultation rates among middle aged men in general practice over three years. British Medical Journal 1990; 301(6753):647-650.

Cook DG, Shaper AG. Re: "Pulmonary function as a predictor of coronary heart disease" [letter]. American Journal of Epidemiology 1990; 132(3):587-588.

Cook DG, Kussick SJ, Shaper AG. The respiratory benefits of stopping smoking. Journal of Smoking-Related Diseases 1990; 1(1):45-58.

Elford J, Phillips A, Thomson AG, Shaper AG. Migration and geographic variations in blood pressure in Britain. British Medical Journal 1990; 300(6720):291-295.

Griffioen A. Alcohol and blood pressure: a cross sectional study of relationships in men and women. Thesis: MSc. 1990 University of London.

Perry IJ. Obesity, physical activity, alcohol intake and the prevalence of non-insulin dependent diabetes mellitus. Thesis: MSc. 1990 University of London.

Phillips AN, Thompson SG, Pocock SJ. Prognostic scores for detecting a high risk group: estimating the sensitivity when applied to new data. Statistics in Medicine 1990; 9(10):1189-1198.

Shaper AG. Alcohol and mortality: a review of prospective studies. British Journal of Addiction 1990; 85(7):837-847.

Walker M, Phillips A, Shaper AG. Blood cholesterol, social class and height [letter]. Journal of Public Health Medicine 1990; 12(2):142-143.

Wannamethee G, Shaper AG. Weight change in middle-aged British men: implications for health. European Journal of Clinical Nutrition 1990; 44(2):133-142.

Wannamethee G, Shaper AG. Weight change, perceived health status and mortality in middle-aged British men. Postgraduate Medical Journal 1990; 66(781):910-913.

Whincup PH, Cook DG, Phillips AN, Shaper AG. ABO blood group and ischaemic heart disease in British men. British Medical Journal 1990; 300(6741):1679-1682.

1989

Cook DG, Shaper AG. Breathlessness, angina pectoris and coronary artery disease. American Journal of Cardiology 1989; 63(13):921-924.

Cook DG, Shaper AG, Macfarlane PW. Using the WHO (Rose) angina questionnaire in cardiovascular epidemiology. International Journal of Epidemiology 1989; 18(3):607-613.

Elford J, Phillips AN, Thomson AG, Shaper AG. Migration and geographic variations in ischaemic heart disease in Great Britain. Lancet 1989; 1(8634):343-346.

Elford J, Shaper AG. Heart disease risks [letter]. Nature 1989; 340(6234):514.

Elford J. Migration and ischaemic heart disease in the British Regional Heart Study. Thesis: PhD. 1989 University of London.

Phillips A, Shaper AG, Whincup PH. Association between serum albumin and mortality from cardiovascular disease, cancer, and other causes. Lancet 1989; 2(8677):1434-1436. (published erratum appears in Lancet 1990;335(8682):180).

Phillips A, Shaper AG. Relative weight and major ischaemic heart disease events in hypertensive men. [Review]. Lancet 1989; 1(8645):1005-1008.

Phillips AN, Shaper AG. Secondary prevention of coronary heart disease (letter). Lancet 1989;71-72.

Phillips AN, Pocock SJ. Sample size requirements for prospective studies, with examples for coronary heart disease. Journal of Clinical Epidemiology 1989; 42(7):639-648.

Pocock SJ, Ashby D, Shaper AG, Walker M, Broughton PM. Diurnal variations in serum biochemical and haematological measurements. Journal of Clinical Pathology 1989; 42(2):172-179.

Pocock SJ, Shaper AG, Phillips AN. Concentrations of high density lipoprotein cholesterol, triglycerides, and total cholesterol in ischaemic heart disease. British Medical Journal 1989; 298(6679):998-1002.

Shaper AG, Phillips AN, Pocock SJ. Plasma cholesterol, coronary heart disease and cancer (letter). British Medical Journal 1989; 298:1381.

Walker M, Shaper AG, Phillips AN, Cook DG. Short stature, lung function and risk of a heart attack. International Journal of Epidemiology 1989; 18(3):602-606.

Wannamethee G, Shaper AG. Body weight and mortality in middle aged British men: impact of smoking. British Medical Journal 1989; 299(6714):1497-1502.

Whincup PH, Cook DG, Shaper AG. Early influences on blood pressure: a study of children aged 5-7 years. British Medical Journal 1989; 299(6699):587-591.

Whincup PH, Cook DG, Shaper AG. Blood pressure measurement in children: the importance of cuff bladder size. Journal of Hypertension 1989; 7(10):845-850.

1988

Bruce NG, Shaper AG, Walker M, Wannamethee G. Observer bias in blood pressure studies. Journal of Hypertension 1988; 6(5):375-380.

Cook DG, Shaper AG. Breathlessness, lung function and the risk of heart attack. European Heart Journal 1988; 9(11):1215-1222.

Phillips AN, Shaper AG, Pocock SJ, Walker M, Macfarlane PW. The role of risk factors in heart attacks occurring in men with pre-existing ischaemic heart disease. British Heart Journal 1988; 60(5):404-410.

Phillips AN, Shaper AG, Pocock SJ, Walker M. Parental death from heart disease and the risk of heart attack. European Heart Journal 1988; 9(3):243-251.

Pocock SJ, Shaper AG, Ashby D, Delves HT, Clayton BE. The relationship between blood lead, blood pressure, stroke, and heart attacks in middle-aged British men. Environmental Health Perspectives 1988; 78:23-30.

Pocock SJ, Delves HT, Ashby D, Shaper AG, Clayton BE. Blood cadmium concentrations in the general population of British middle-aged men. Human Toxicology 1988; 7(2):95-103.

Pocock SJ, Shaper AG, Phillips AN, Walker M. Prediction of men at high risk of heart attack and its relevance to pilots. European Heart Journal 1988; 9 Suppl G:25-30.

Shaper AG, Wannamethee G, Whincup P. Alcohol and blood pressure in middle-aged British men. Journal of Human Hypertension 1988; 2(2):71-78.

Shaper AG, Ashby D, Pocock SJ. Blood pressure and hypertension in middle-aged British men. Journal of Hypertension 1988; 6(5):367-374.

Shaper AG, Wannamethee G, Walker M. Alcohol and mortality in British men: explaining the U-shaped curve. Lancet 1988; 2(8623):1267-1273.

Walker M, Shaper AG, Wannamethee G. Height and social class in middle-aged British men. Journal of Epidemiology & Community Health 1988; 42(3):299-303.

Wannamethee G, Shaper AG. Changes in drinking habits in middle-aged British men. Journal of the Royal College of General Practitioners 1988; 38(315):440-442.

Wannamethee G, Shaper AG. Men who do not drink: a report from the British Regional Heart Study. International Journal of Epidemiology 1988; 17(2):307-316.

Weatherall R, Shaper AG. Overweight and obesity in middle-aged British men. European Journal of Clinical Nutrition 1988; 42(3):221-231.

Whincup PH, Cook DG, Shaper AG. Social class and height [letter]. British Medical Journal 1988; 297(6654):980-981.

Whincup PH, Cook DG, Shaper AG, Macfarlane DJ, Walker M. Blood pressure in British children: associations with adult blood pressure and cardiovascular mortality. Lancet 1988; 2(8616):890-893.

1987

Cook DG. Respiratory function, smoking and coronary heart disease in British men. Thesis: PhD. 1987 University of London.

Flegel KM, Shipley MJ, Rose G. Risk of stroke in non-rheumatic atrial fibrillation. Lancet 1987; 1(8532):526-529. (published erratum appears in Lancet 1987; 1(8537)::878).

Johnston DW, Cook DG, Shaper AG. Type A behaviour and ischaemic heart disease in middle aged British men. British Medical Journal 1987; 295(6590):86-89.

Macfarlane PW. British Regional Heart Study: the electrocardiogram and risk of myocardial infarction on follow-up. Journal of Electrocardiology 1987; 20 Suppl:53-56.

Pocock SJ, Shaper AG, Cook DG, Phillips AN, Walker M. Social class differences in ischaemic heart disease in British men. Lancet 1987; 2(8552):197-201.

Shaper AG, Phillips AN, Pocock SJ, Walker M. Systolic and diastolic blood pressures in the prediction of heart attacks and stroke. Journal of Hypertension 1987; 5(6):41.

Shaper AG, Pocock SJ. Risk factors for ischaemic heart disease in British men [editorial]. British Heart Journal 1987; 57(1):11-16.

Shaper AG, Phillips AN, Pocock SJ, Walker M. Alcohol and ischaemic heart disease in middle aged British men. British Medical Journal 1987; 294(6574):733-737.

Shaper AG, Pocock SJ, Phillips AN, Walker M. A scoring system to identify men at high risk of a heart attack. Health Trends 1987; 19(2):37-39.

Shaper AG. Risk factors for ischaemic heart disease. Health Trends 1987; 19:3-8.

Walker M. Mortality and social class [letter]. Lancet 1987; 2(8561):746.

Walker M, Shaper AG, Cook DG. Non-participation and mortality in a prospective study of cardiovascular disease. Journal of Epidemiology & Community Health 1987; 41(4):295-299.

Whincup PH, Cook DG, Shaper AG. Alcohol consumption in England and Wales (letter). British Medical Journal 1987; 295(6608): 1278-1279.

1986

Ashby D, Pocock SJ, Shaper AG. Ordered polytomous regression: An example relating serum biochemistry and haematology to alcohol consumption. The Journal of the Royal Statistical Society 1986; 35(3):289-301. Broughton PM, Holder R, Ashby D. Long-term trends in biochemical data obtained from two population surveys. Annals of Clinical Biochemistry 1986; 23(4):474-486.

Cook DG, Shaper AG, Pocock SJ, Kussick SJ. Giving up smoking and the risk of heart attacks. A report from The British Regional Heart Study. Lancet 1986; 2(8520):1376-1380.

Cook DG, Shaper AG, Thelle DS, Whitehead TP. Serum uric acid, serum glucose and diabetes: relationships in a population study. Postgraduate Medical Journal 1986; 62(733):1001-1006.

Cook DG. Can we detect an effect of unemployment on cardiovascular morbidity or mortality? Postgraduate Medical Journal 1986; 62(730):801-804.

Phillips AN. Statistical issues in prospective studies of risk factors for ischaemic heart disease. Thesis: PhD. 1986 University of London.

Pocock SJ, Shaper AG, Phillips AN, Walker M, Whitehead TP. High density lipoprotein cholesterol is not a major risk factor for ischaemic heart disease in British men. British Medical Journal 1986; 292(6519):515-519.

Shaper AG. Identification of risk factors for coronary heart disease. In Proceedings of the Glasgow heart disease symposium: Lipoproteins and coronary heart disease. Editors: Shepherd J, Packard CJ, Lorimer AR, Lawrie TDV, Morgan HG, Brownlie SM. Publishers: Blantyre Printing London & Glasgow 1986; 77-86.

Shaper AG, Pocock SJ, Phillips AN, Walker M. Identifying men at high risk of heart attacks: strategy for use in general practice. British Medical Journal 1986; 293(6545):474-479.

1985

Cook DG. A critical view of the unemployment and health debate. The Statistician 1985;34(1): 73-82. Pocock SJ, Shaper AG, Ashby D, Delves HT. Blood lead and blood pressure in middle-aged men. In Lead Environmental Health - The Current Issues. Publishers: Division of Occupational Medicine Duke University, Durham North Carolina, USA. 1985; 75-80.

Pocock SJ, Shaper AG, Powell P. The British Regional Heart Study: cardiovascular disease and water quality. In Drinking Water and Cardiovascular Disease. Publishers: Water Research Centre, Marlow, England. 1985; Chapter 12: 111-127.

Shaper AG, Pocock SJ. British blood cholesterol values and the American consensus [letter]. British Medical Journal 1985;291(6493): 480-481.

Shaper AG, Pocock SJ, Ashby D, Walker M, Whitehead TP. Biochemical and haematological response to alcohol intake. Annals of Clinical Biochemistry 1985;22 (1): 50-61.

Shaper AG, Pocock SJ, Walker M, Phillips AN, Whitehead TP, Macfarlane PW. Risk factors for ischaemic heart disease: the prospective phase of the British Regional Heart Study. Journal of Epidemiology & Community Health 1985; 39(3):197-209.

Shaper AG, Pocock SJ. Blood lead and blood pressure [editorial]. British Medical Journal 1985; 291(6503):1147-1149.

Walker M. A comparative study of non-responders and responders in health research. Thesis: MA. 1985 University of Leeds.

1984

Ashby D. A Statistical investigation of the relationship of serum biochemistry and haematology to alcohol consumption. Thesis: PhD. 1984 University of London. Cook DG, Shaper AG. Unemployment and health. In Recent Advances in Occupational Health. Editors: Harrington, J. M. Publishers: Churchill Livingstone, London 1984; Chapter 18, 233-249.

Kussick S. The prevalence of chronic bronchitis in a cohort of 7735 middle-aged British men. Thesis: MSc. 1984. University of London.

Pocock SJ, Shaper AG, Ashby D, Delves T, Whitehead TP. Blood lead concentration, blood pressure, and renal function. BMJ 1984; 289(6449): 872-874.

Shaper AG, Cook DG, Walker M, Macfarlane PW. Recall of diagnosis by men with ischaemic heart disease. British Heart Journal 1984; 51(6): 606-611.

Shaper AG, Cook DG, Walker M, Macfarlane PW. Prevalence of ischaemic heart disease in middle aged British men. British Heart Journal 1984; 51(6): 595-605.

Shaper AG. Geographic variations in cardiovascular mortality in Great Britain. [Review]. British Medical Bulletin 1984; 40(4): 366-373.

Walker M, Shaper AG. Follow-up of subjects in prospective studies based in general practice. Journal of the Royal College of General Practitioners 1984;34(264): 365-370.

1983

Broughton PMG, Holder R, Anglesea J. Long term trends in biochemical data. In Proceedings of the Medinfo 83 Seminars. Editor: Fokkens O. 1983; 288-289. Cook DG, Pocock SJ. Multiple Regression in geographical mortality studies, with allowance for spatially correlated errors. Biometrics 1983; 39(2): 361-371.

Pocock SJ, Shaper AG, Walker M, Wale CJ, Clayton B, Delves T et al. Effects of tap water lead, water hardness, alcohol, and cigarettes on blood lead concentrations. Journal of Epidemiology & Community Health 1983; 37(1): 1-7.

Shaper AG, Pocock SJ, Packham RF, Lacey RF, Powell P. Softness of drinking water and cardiovascular disease - practical implications of recent research. Health Trends 1983;15: 22-24.

Thelle DS, Shaper AG, Whitehead TP, Bullock DG, Ashby D, Patel I. Blood lipids in middle-aged British men. British Heart Journal 1983; 49(3): 205-213.

1982

Cook DG, Cummins RO, Bartley MJ, Shaper AG. Health of unemployed middle-aged men in Great Britain. Lancet 1982; 1(8284):1290-1294. Cripps P. Alcohol and disease: an investigation into the health of non-drinkers. Thesis: MSc. 1982 University of London.

Cummins RO, Cook DG, Hume RC, Shaper AG. Tranquillizer use in middle-aged British men. Journal of the Royal College of General Practitioners 1982; 32(245):745-752.

Pocock SJ, Cook DG, Shaper AG. Analysing geographic variation in cardiovascular mortality: Methods and results. The Journal of the Royal Statistical Society 1982; 145(3): 313-341.

Shaper AG, Pocock SJ, Walker M, Wale CJ, Clayton B, Delves HT et al. Effects of alcohol and smoking on blood lead in middle-aged British men. BMJ 1982; 284(6312):299-302.

1981

Cummins RO, Shaper AG, Walker M, Wale CJ. Smoking and drinking by middle-aged British men: effects of social class and town of residence. BMJ 1981; 283(6305):1497-1502. Cummins RO, Shaper AG, Walker M. Methodological problems with estimation of salt intake (letter). Lancet 1981; 1(8234):1373-1374.

Masironi R, Shaper AG. Epidemiological studies of health effects of water from different sources. Annual Review of Nutrition 1981; 1:390-400.

Pocock SJ, Shaper AG, Packham RF. Studies of water quality and cardiovascular disease in the United Kingdom. Science of the Total Environment 1981; 18:25-34.

Pocock SJ, Cook DG, Beresford SAA. Regression of area mortality rates on explanatory variables: What weighting is appropriate? The Journal of the Royal Statistical Society 1981; 30(3):286-295.

Shaper AG, Pocock SJ, Walker M, Cohen NM, Wale CJ, Thomson AG. British Regional Heart Study: cardiovascular risk factors in middle-aged men in 24 towns. BMJ 1981; 283(6285):179-186.

1980

Pocock SJ, Shaper AG, Cook DG, Packham RF, Lacey RF, Powell P et al. British Regional Heart Study: geographic variations in cardiovascular mortality, and the role of water quality. BMJ 1980; 280 (6226):1243-1249.

Shaper AG, Packham RF, Pocock SJ. The British Regional Heart Study: cardiovascular mortality and water quality. Journal of Environmental Pathology & Toxicology 1980; 4(2-3):89-111

Doctoral Degrees

Aggio D. Longitudinal patterns of physical activity from midlife to old age: predictors and consequences for cardiovascular disease morbidity and mortality risks. 2020. University College London

Ashby D. A statistical investigation of the relationship of serum biochemistry and haematology to alcohol consumption. 1984. University of London.

Atkins JL. Body composition, dietary patterns, cardiovascular disease and mortality in older age. 2016. University College London

Bruce N.G. An investigation of geographic blood pressure variations among men and women in Great Britain. 1991. University of London.

Cook D.G. Respiratory function, smoking and coronary heart disease in British men. 1987. University of London.

Elford J. Migration and ischaemic heart disease in the British Regional Heart Study. 1989. University of London.

Emberson J. Re-assessing the role of major coronary risk factors: implications of measurement imprecision and changes over time. 2004. University of London.

Hardoon SL. Analysing recent time trends in coronary heart disease and type 2 diabetes. 2011. University College London

Lampe F.C. Chest pain on questionnaire and coronary heart disease in British men. 2003. University of London.

Liljas AEM. The relationship of sensory impairments with cardiovascular disease and mortality, disability and frailty in older age: longitudinal cohort studies using the British Regional Heart Study and the English Longitudinal Study of Ageing. 2017. University College London

Morris J. Loss of employment and ill health. 1992 University of London.

Perry I.J. Risk factors for non-insulin dependent diabetes mellitus in middle-aged men. 1996. University of London.

Phillips A.N. Statistical issues in prospective studies of risk factors for ischaemic heart disease. 1986. University of London.

Ramsay S.E. Health inequalities in British men: the impact of socio-economic circumstances at different stages of the life-course. 2009. University College London.

Sartini C. Seasonal and diurnal variations in cardiovascular risk factors and cardiovascular disease in older British men. 2019. University College London.

Tang J.L. Giving up smoking and the risk of ischaemic heart disease. 1991. University of London.

Wannamethee S.G. Alcohol, cardiovascular disease and all cause mortality in British middle-aged men. 1992. University of London

Whincup P.H. A study of blood pressure in children in nine British towns. 1991 University of London.

PhD Thesis in progess:

Ahmed A. Primary prevention of stroke in older populations in the UK . University College London.

Master Degrees

Cripps P. Alcohol and disease: an investigation into the health of non-drinkers. MSc. 1982 University of London.

Griffin M. High resolution ultrasound increasing the predictive value of the British Regional Heart Study risk score. MSc. 1996 University of London.

Griffioen A. Alcohol and blood pressure: a cross sectional study of relationships in men and women. MSc. 1990 University of London.

Kussick S. The prevalence of chronic bronchitis in a cohort of 7735 middle-aged British men. MSc. 1984 University of London.

Lennon L.T. Can the world wide web be used to improve health knowledge management in the British Regional Heart Study? MSc. 2002 University College London.

Perry I.J. Obesity, physical activity, alcohol intake and the prevalence of non-insulin dependent diabetes mellitus. MSc. 1990 University of London.

Thomas M.C. Changing prevalence of self-reported type 2 diabetes in older British men, 1978-2005. MSc 2006 London School of Hygiene & Tropical Medicine.

Walker M. A comparative study of non-responders and responders in health research. MA.1986 University of Leeds.