Institute of Epidemiology & Health Care



List of Whitehall II publications by Whitehall II researchers, ordered alphabetically by first author. Please see below Consortium papers where Whitehall II data were used.

  • The Beck Depression Inventory and General Health Questionnaire as measures of depression in the general population: A validation study with the Composite International Diagnostic Interview as the gold standard. Aalto, A.-M., Elovainio, M., Kivimäki, M., Uutela, A., Pirkola, S. Psychiatry Research, 197, 163-171, 2012 (PMID: 22365275)
  • Does Framingham stroke risk profile predict white-matter changes in late-life depression? Allan, C., Sexton, C., Kalu, U., McDermott, L., Kivimäki, M., Singh-Manoux, A., Mackay, C., Ebmeier, K. International Psychogeriatrics, 24, 524-531, 2012 (PMID: 22088779)
  • Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration. Angelakopoulou A, […] Marmot M, […] Kivimaki M, Kumari M, […] Hingorani AD et al. Eur Heart J. 2012 Feb;33(3):393-407. (PMID: 21804106)
  • Bidirectional association between physical activity and symptoms of anxiety and depression: the Whitehall II study. Azevedo Da Silva M, Singh-Manoux A, Brunner EJ, Kaffashian S, Shipley MJ, Kivimäki M, Nabi H.  Eur J Epidemiol (2012) Jul;27(7):537-46, 2012 (PMID: 22623145)
  • Validating self-reported strokes in a longitudinal UK cohort study (Whitehall II): Extracting information from hospital medical records versus the Hospital Episode Statistics database. Britton A, Milne B, Butler T, Sanchez-Galvez A, Shipley M, Rudd A, Wolfe CD, Bhalla A, Brunner EJ.  BMC Med Res Methodology 21;12:83, 2012 (PMID: 22720999)
  • Hostility and cellular aging in men from the Whitehall II cohort. Brydon L, Lin J, Butcher L, Hamer M, Erusalimsky JD, Blackburn EH, Steptoe A.  Biol Psychiatry. 2012 May 1;71(9):767-73. (PMID: 21974787)
  • Gene-targeted analysis of copy number variants identifies 3 novel associations with coronary heart disease traits. Costelloe SJ, El-Sayed Moustafa JS, Drenos F, Palmen J, Qiao L, Whiting S, Thomas M, Kivimaki M, Kumari M, Hingorani AD, Tzoulaki I, Marjo-Riitta J, Aimo R, Hartikainen AL, Pouta A, Walters RG, Blakemore AI, Humphries SE, Coin LJ, Talmud PJ.  Circ Cardiovasc Genet 5(5):555-60, 2012 (PMID: 22972876)
  • Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. Dastani Z et al. PLoS Genet. 2012 Mar;8(3):e1002607. (PMID: 22479202)
  • Organisational justice and cognitive function in middle-aged employees: the Whitehall II study. Elovainio M, Singh-Manoux A, Ferrie JE, Shipley M, Gimeno D, De Vogli R, Vahtera J, Virtanen M, Jokela M, Marmot MG, Kivimäki M.  J Epidemiol Community Health. 2012 Jun;66(6):552-6. (PMID: 21084589)
  • Cross-cultural comparison of correlates of quality of life and health status: the Whitehall II Study (UK) and the Western New York Health Study (US). Franco OH, Wong YL, Kandala NB, Ferrie JE, Dorn JM, Kivimäki M, Clarke A, Donahue RP, Manoux AS, Freudenheim JL, Trevisan M, Stranges S. Eur J Epidemiol. 2012 Mar 4 [Epub ahead of print]. (PMID: 22392587)
  • Integration of genetics into a systems model of electrocardiographic traits using HumanCVD BeadChip. Gaunt TR, Shah S, Nelson CP, Drenos F, Braund PS et al. Circulation Cardiovascular Genetics, 5(6):630-8, 2012 (PMID: 23139254)
  • Early-life stress and recurrent psychological distress over the lifecourse predict divergent cortisol reactivity patterns in adulthood. Goldman-Mellor S, Hamer M, Steptoe A. Psychoneuroendocrinology 37(11):1755-68, 2012 (PMID: 22475549)
  • Loneliness and stress-related inflammatory and neuroendocrine responses in older men and women. Hackett RA, Hamer M, Endrighi R, Brydon L, Steptoe A. Psychoneuroendocrinology, 37(11):1801-1809,  2012 (PMID: 22503139)
  • Low conscientiousness and risk of all-cause, cardiovascular and cancer mortality over 17 years: Whitehall II cohort study. Hagger-Johnson G, Sabia S, Nabi H, Brunner E, Kivimaki M, Shipley M, Singh-Manoux A. J Psychosom Res 73(2):98-103, 2012 (PMID: 22789411)
  • Physical Activity, Sedentary Time, and Pericardial Fat in Healthy Older Adults. Hamer M, Venuraju SM, Urbanova L, Lahiri A, Steptoe A. Obesity 2012 Mar 8 [epub ahead of print] (PMID: 22402739)
  • Cortisol responses to mental stress and the progression of coronary artery calcification in healthy men and women. Hamer M, Endrighi R, Venuraju SM, Lahiri A, Steptoe A. PLoS One. 2012;7(2):e31356. (PMID: 22328931)
  • Objectively assessed physical activity, sedentary time, and coronary artery calcification in healthy older adults. Hamer M, Venuraju SM, Lahiri A, Rossi A, Steptoe A. Arterioscler Thromb Vasc Biol. 2012 Feb;32(2):500-5. (PMID: 22075247)
  • Cortisol Responses to Mental Stress and Incident Hypertension in Healthy Men and Women. Hamer M, Steptoe A. J Clin Endocrinol Metab. 2012 Jan; 97(1):E29-34 (PMID: 22031509)
  • Longitudinal patterns in physical activity and sedentary behaviour from mid-life to early old age: a substudy of the Whitehall II cohort. Hamer M, Kivimaki M, Steptoe A. J Epidemiol Community Health, 66(12):1110-5, 2012 (PMID: 22791800)
  • Physical activity and inflammatory markers over 10 years: follow-up in men and women from the Whitehall II cohort study. Hamer M, Sabia S, Batty GD, Shipley MJ, Tabák AG, Singh-Manoux A, Kivimaki M.  Circulation 126(8):928-33, 2012 (PMID: 22891048)
  • Psychological distress as a risk factor for cerebrovascular disease mortality: A population study in 68,652 adults. Hamer, M., Kivimäki, M., Stamatakis, E., Batty, G. D. Canadian Medical Association Journal, 184, 1461-1466, 2012 (PMID: 22711734)
  • Longitudinal patterns in physical activity and sedentary behaviour from mid-life to early old age: a substudy of the Whitehall II cohort. Hamer M, Kivimaki M, Steptoe A.  Journal of Epidemiology and Community Health, 66(12):1110-5, 2012 (PMID: 22791800)
  • Rising adiposity curbing decline in the incidence of myocardial infarction: 20-year follow-up of British men and women in the Whitehall II cohort. Hardoon SL, Morris RW, Whincup PH, Shipley MJ, Britton AR, Masset G, Stringhini S, Sabia S, Kivimaki M, Singh-Manoux A, Brunner EJ. Eur Heart J. 2012 Feb; 33(4):478-85, 2012 (21653562)
  • Work Stress, Obesity and the Risk of Type 2 Diabetes: Gender-Specific Bidirectional Effect in the Whitehall II Study. Heraclides AM, Chandola T, Witte DR, Brunner EJ. Obesity (Silver Spring). Feb; 20(2):428-33, 2012 (PMID: 21593804)
  • Evaluation of common genetic variants identified by GWAS for early onset and morbid obesity in population-based samples. den Hoed M, Luan J, Langenberg C, Cooper C, Sayer AA, Jameson K, Kumari M, Kivimaki M, Hingorani AD, Grøntved A, Khaw KT, Ekelund U, Wareham NJ, Loos RJ.  Int J Obes. 2012 Mar 20 [Epub ahead of print]. (PMID: 22430306)
  • The association between waist circumference and risk of mortality considering body mass index in 65-74 year olds: a meta-analysis of 29 cohorts involving more than 58 000 elderly. de Hollander, E. et al. International Journal of Epidemiology, 41, 805-817, 2012 (PMID: 22467292)
  • Short sleep duration is associated with shorter telomere length in healthy men: findings from the Whitehall II cohort study. Jackowska M, Hamer M, Carvalho LA, Erusalimsky JD, Butcher L, Steptoe A. PLoS One, 7(10):e47292, 2012 (PMID: 23144701)
  • Differential associations of job control components with mortality: A cohort study, 1986-2006. Joensuu, M., Kivimäki, M., Koskinen, A., Kouvonen, A., Pulkki-Råback, L., Vahtera, J., Virtanen, M., Väänänen, A. American Journal of Epidemiology, 175, 609-619, 2012 (PMID: 22392475)
  • Determinants of aortic stiffness: 16-year follow-up of the Whitehall II study. Johansen NB, Vistisen D, Brunner EJ, Tabák AG, Shipley MJ, Wilkinson IB, McEniery CM, Roden M, Herder C, Kivimäki M, Witte DR. PLoS One 2012;7(5):e37165, 2012 (PMID: 22629363)
  • A genetic instrument for Mendelian randomization of fibrinogen. Ken-Dror G, Humphries SE, Kumari M, Kivimaki M, Drenos F. Eur J Epidemiol. 2012 Mar 3 (PMID: 22388766)
  • Vascular Risk Status as a Predictor of Later-Life Depressive Symptoms: A Cohort Study. Kivimaki M, Shipley MJ, Allan CL, Sexton CE, Jokela M, Virtanen M, et al. Biol Psychiatry. 2012 Mar 16 [Epub ahead of print] (PMID: 22425413)
  • Antidepressant drug use and future diabetes risk. Kivimäki M, Batty GD. Diabetologia. 2012 Jan; 55(1):10-2 (PMID: 22038524)
  • Social support and the likelihood of maintaining and improving levels of physical activity: the Whitehall II Study. Kouvonen A, De Vogli R, Stafford M, Shipley MJ, Marmot MG, Cox T, Vahtera J, Väänänen A, Heponiemi T, Singh-Manoux A, Kivimäki M. . Eur J Public Health. 2012 Aug;22(4):514-8.(PMID: 21750013)
  • A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Manning A […] Brunner E, […], Hingorani A, […], Kivimaki M, […], Kumari M, […]. Marmot M, […], Langenberg C et al. Nat Genet. 13;44(6):659-69, 2012 (PMID: 22581228)
  • Economic difficulties and subsequent sleep problems: evidence from British and Finnish occupational cohorts. Lallukka, T., Ferrie, J, Kivimäki, M., Shipley, M. J., Rahkonen, O., Lahelma, E. Sleep Medicine, 13, 680-685, 2012 (PMID: 22445231)
  • Why do males in Scotland die younger than those in England? Evidence from three prospective cohort studies. McCartney, G., Shipley, M., Hart, C., Davey Smith, G., Kivimäki, M., Walsh, D., Watt, G. C., Batty, G. D. PLoS ONE, 7, e38860, 2012 (PMID: 22808017)
  • Consent to DNA collection in epidemiological studies: findings from the Whitehall II cohort and the English Longitudinal Study of Ageing. Meisel SF, Shankar A, Kivimaki M, Wardle J. Genet Med. 2012 Feb;14(2):201-6. (PMID: 22261757)
  • Altruism and participation in longitudinal health research? Insights from the Whitehall II Study. Mein G, Seale C, Rice H, Johal S, Ashcroft RE, Ellison G, Tinker A. Soc Sci Med [Epub ahead of print], 2012 (PMID: 23031604)
  • Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Morris, A. P. et al Nature Genetics, 44, 981-990, 2012 (PMID: 22885922)
  • Bidirectional association between depression and obesity in middle-aged and older women. Pan A, Sun Q, Czernichow S, Kivimaki M, Okereke OI, Lucas M, et al. Int J Obes (Lond). 2012 Apr;36(4):595-602. (PMID: 21654630)
  • Cholesteryl Ester Transfer Protein (CETP) polymorphisms affect mRNA splicing, HDL levels, and sex-dependent cardiovascular risk. Papp AC, Pinsonneault JK, Wang D, Newman LC, Gong Y, Johnson JA, Pepine CJ, Kumari M, Hingorani AD, Talmud PJ, Shah S, Humphries SE, Sadee W. PLoS One. 2012;7(3):e31930. (PMID: 22403620)
  • Association between psychological distress and mortality: an individual participant pooled analysis of ten prospective cohort studies. Russ, T. C., Stamatakis, E., Hamer, M., Starr, J. M., Kivimäki, M., Batty G. D. British Medical Journal, 345, e4933, 2012 (PMID: 22849956)
  • Effect of Intensity and Type of Physical Activity on Mortality: Results From the Whitehall II Cohort Study. Sabia S, Dugravot A, Kivimaki M, Brunner E, Shipley MJ, Singh-Manoux A. American journal of public health, 2012 Apr; 102(4):698-704 (PMID: 21940933)
  • Impact of smoking on cognitive decline in early old age: the Whitehall II cohort study. Sabia S, Elbaz A, Dugravot A, Head J, Shipley M, Hagger-Johnson G, Kivimaki M, Singh-Manoux A. Arch Gen Psychiatry (2012) Jun;69(6):627-35, 2012 (PMID: 22309970)
  • Influence of individual and combined healthy behaviours on successful aging. Sabia S, Singh-Manoux A, Hagger-Johnson G, Cambois E, Brunner EJ, Kivimaki M. Canadian Medical Association Journal, 184(18):1985-92, 2012 (PMID: 23091184)
  • Large-Scale Gene-Centric Meta-Analysis across 39 Studies Identifies Type 2 Diabetes Loci. Saxena R, [...], Drenos F, [...], Humphries SE, [...], Kivimaki M, [...], Kumari M, [...], Shah S, [...], Casas JP, [...], Hingorani AD, [...], Talmud PJ, […], Keating BJ.  Am J Hum Genet. 3012 Mar 9;90(3):410-425 (PMID: 22325160)
  • Trajectories of sleep complaints from early mid-life to old age: Longitudinal modeling study. Salo, P., Vahtera, J., Ferrie, J. E., Akbaraly, T., Goldberg, M., Zins, M., Pentti, J., Virtanen, M., Shipley, M. J., Singh-Manoux, A., Dauvilliers, Y., Kivimäki, M. Sleep, 35, 559-569, 2012 (PMID: 22467994)
  • Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Scott, R.A. et al. Nature Genetics, 44, 991-1005, 2012 (PMID: 22885924)
  • No Interactions Between Previously Associated 2-Hour Glucose Gene Variants and Physical Activity or BMI on 2-Hour Glucose Levels. Scott R Scott RA,[…] Brunner E, […] Hingorani A, […] Kivimaki M, Kumari M, Marmot M, […]  Langenberg C. Diabetes. 2012 May;61(5):1291-6. (PMID: 22415877)
  • Psychological distress, cortisol stress response and subclinical coronary calcification. Seldenrijk A, Hamer M, Lahiri A, Penninx BW, Steptoe A. Psychoneuroendocrinology. 2012 Jan; 37(1):48-55 (PMID: 21621333)
  • Timing of onset of cognitive decline: results from Whitehall II prospective cohort study. Singh-Manoux A, Kivimaki M, Glymour MM, Elbaz A, Berr C, Ebmeier KP, Ferrie JE, Dugravot A. British Medical Journal. 2012 Jan 5; 344 (PMID: 22223828)
  • Obesity phenotypes in midlife and cognition in early old age: the Whitehall II cohort study. Singh-Manoux A, Czernichow S, Elbaz A, Dugravot A, Sabia S, Hagger-Johnson G, Kaffashian S, Zins M, Brunner EJ, Nabi H, Kivimäki M. Neurology 79(8):755-62, 2012 (PMID: 22915175)
  • Stress and cardiovascular disease. Steptoe A, Kivimäki M. Nature Reviews Cardiology. 2012 Apr 3;9(6):360-70 (PMID: 22473079)
  • Repeated job strain and the risk of depression: longitudinal analyses from the Whitehall II study. Stansfeld SA, Shipley MJ, Head J, Fuhrer R. American  Journal of Public Health, 102(12):2360-6, 2012 (PMID: 23078508)
  • Socioeconomic Status, Structural and Functional Measures of Social Support, and Mortality: The British Whitehall II Cohort Study, 1985-2009. Stringhini S, Berkman L, Dugravot A, Ferrie JE, Marmot M, Kivimaki M, Singh-Manoux A. Am J Epidemiol. 15;175(12):1275-83, 2012 (PMID: 22534202)
  • Contribution of modifiable risk factors to social inequalities in type 2 diabetes: prospective Whitehall II cohort study. Stringhini S, Tabak AG, Akbaraly TN, Sabia S, Shipley MJ, Marmot MG, Brunner EJ, Batty GD, Bovet P, Kivimäki M. BMJ 21;345:e5452, 2012 (PMID: 22915665)
  • Prediabetes: A high-risk state for developing diabetes. Tabák A, Herder C, Rathmann W, Brunner EJ, Kivimäki M. Lancet, 379(9833):2279-90 2012 (PMID: 22683128)
  • Adiponectin Trajectories Before Type 2 Diabetes Diagnosis: Whitehall II Study. Tabák AG, Carstensen M, Witte DR, Brunner EJ, Shipley MJ, Jokela M, Roden M, Kivimäki M, Herder C. Diabetes Care [Epub ahead of print], 2012 (PMID: 22933430)
  • Overtime work as a predictor of major depressive episode: a 5-year follow-up of the Whitehall II study. Virtanen M, Stansfeld SA, Fuhrer R, Ferrie JE, Kivimäki M. PLoS One, 7(1):e30719, 2012 (PMID: 22295106)
  • Long working hours and coronary heart disease: a systematic review and meta-analysis. Virtanen, M., Heikkilä, K., Jokela, M., Ferrie, J. E., Batty, G. D., Vahtera, J., Kivimäki, M. American Journal of Epidemiology, 176, 586-596, 2012 (PMID: 22952309)
  • Sex differences in glucose and insulin trajectories prior to diabetes diagnosis: the Whitehall II study Vistisen D, Witte DR, Tabák AG, Brunner EJ, Kivimäki M, Færch K. Acta Diabetol [Epub ahead of print], 2012 (PMID: 22983665)
  • IRS1 gene variants, dysglycaemic metabolic changes and type-2 diabetes risk. Yiannakouris N,  […], Kivimaki M, Hingorani AD, Kumari M, Talmud PJ, Humphries SE. Nutr Metab Cardiovasc Dis. Dec;22(12):1024-30, 2012 (PMID: 21917432)

Consortium papers


  • The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis. Interleukin-6 Receptor Mendelian Randomisation Analysis (IL6R MR) Consortium, Hingorani AD, Casas JP. Lancet, Mar 31;379(9822):1214-24, 2012 (PMID: 22421340)



  • Height and the risk of cause-specific death and vascular morbidity in 1 million adults. Emerging Risk Factors Collaboration (ERFC), International Journal of Epidemiology, 41, 1419-1433, 2012 (PMID: 22825588)
  • C-reactive protein, fibrinogen, and cardiovascular disease prediction. ERFC, Kaptoge, S. et al., New England Journal of Medicine, 367, 1310-1320., 2012 (PMID: 23034020)
  • Lipid-related markers and cardiovascular disease prediction: The Emerging Risk Factors Collaboration. JAMA, 307, 2499-2506, 2012 (PMID: 22797450)


IPD-Work Consortium

  • Comparison of alternative versions of the job demand-control scales in 17 European cohort studies: the IPD-Work consortium. Fransson, E. I., […], Batty, G. D., […], M., Singh-Manoux, A.,[…], Westerlund, H., Zins, M., Theorell, T./Kivimäki, M.A51  BMC Public Health, 12, 62, 2012 (PMID: 22264402)
  • Job strain as a risk factor for leisure-time physical inactivity: an individual-participant meta-analysis of up to 170,000 men and women: the IPD-Work Consortium. Fransson EI, Heikkilä K, Nyberg ST, Zins M, Westerlund H et al. American  Journal of Epidemiology, 176(12):1078-89, 2012 (PMID: 23144364)
  • Job strain and tobacco smoking: An individual-participant data meta-analysis of 166 130 adults in 15 European studies. Heikkilä, K., Nyberg, S. N., Fransson, E. I., […], Steptoe, A., […], Hamer, M., Ferrie, J. E., Singh-Manoux, A., Batty, G. D., Kivimäki, M. PLoS ONE, 7, e35463, 2012 (PMID: 22792154)
  • Job strain and alcohol intake: A collaborative meta-analysis of individual-participant data from 140,000 men and women. Heikkilä, K., Nyberg, S. N., Fransson, E. I., […], Steptoe, A., […], Hamer, M., Ferrie, J. E., Singh-Manoux, A., Batty, G. D., Kivimäki, M. PLoS ONE, 7, e40101, 2012 (PMID: 22792218)
  • Job strain in relation to body mass index: pooled analysis of 160,000 adults from 13 cohort studies. Heikkilä, K., Nyberg, S. N., Fransson, E. I., […], Steptoe, A., […], Hamer, M., Ferrie, J. E., Singh-Manoux, A., Batty, G. D., Kivimäki, M. Journal of Internal Medicine, 272, 65-73, 2012 (PMID: 22077620)
  • Job strain as a risk factor for coronary heart disease: A collaborative meta-analysis of individual participant data. Kivimäki, M., Nyberg, S. T., Batty, G. D., Fransson, E. I., [...] Ferrie, J. E., [...], Jokela, [...], Kumari, M., Madsen, I. E. H., Marmot, M. G., [...], Singh-Manoux, A., [...] Virtanen, M., Westerholm, P. J. M., Westerlund, H., Zins, M., Steptoe, A., Theorell, T.  Lancet, 27;380(9852):1491-1497, 2012 (PMID: 22981903)